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Author Details

Yao Cong
University of Chinese Academy of Sciences
2003
63
28
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36853487A human antibody potently neutralizes RSV by targeting the conserved hydrophobic region of prefusion F.Sci China Life Sci2023
37544111Cryo-EM and cryo-ET of the spike, virion, and antibody neutralization of SARS-CoV-2 and VOCs.Curr Opin Struct Biol2023
37193829Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.Commun Biol2023
36989299Structural insights into constitutive activity of 5-HT<sub>6</sub> receptor.Proc Natl Acad Sci U S A2023
37439022Cryo-EM of α-tubulin isotype-containing microtubules revealed a contracted structure of α4A/β2A microtubules.Acta Biochim Biophys Sin (Shanghai)2023
36921056Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT.Sci Adv2023
35228716Molecular basis of receptor binding and antibody neutralization of Omicron.Nature2022
35501328Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus.Nat Commun2022
36543790Molecular mechanism of antibody neutralization of coxsackievirus A16.Nat Commun2022
35896553Author Correction: A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection.Nat Commun2022
34964428Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein.Emerg Microbes Infect2022
35169135Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies.Nat Commun2022
33277323Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM.Sci Adv2021
33531497Cryo-EM of mammalian PA28αβ-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28αβ.Nat Commun2021
34930910Conformational dynamics of the Beta and Kappa SARS-CoV-2 spike proteins and their complexes with ACE2 receptor revealed by cryo-EM.Nat Commun2021
34871179Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM.Proc Natl Acad Sci U S A2021
34557519Architecture of Dispatched, a Transmembrane Protein Responsible for Hedgehog Release.Front Mol Biosci2021
34702852The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.Nat Commun2021
34782772The cryo-EM structure of the chloroplast ClpP complex.Nat Plants2021
34174188Cryo-EM study of patched in lipid nanodisc suggests a structural basis for its clustering in caveolae.Structure2021
34006855Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections.Nat Commun2021
34330908A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection.Nat Commun2021
33431876Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.Nat Commun2021
30652025Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses.Cell Discov2019
31939165TRiC/CCT Chaperonin: Structure and Function.Subcell Biochem2019
31776446A complex structure of arrestin-2 bound to a G protein-coupled receptor.Cell Res2019
31492816An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity.Proc Natl Acad Sci U S A2019
30735603Hetero-oligomeric CPN60 resembles highly symmetric group-I chaperonin structure revealed by Cryo-EM.Plant J2019
30792173Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.Mol Cell2019
29093091A 3.0-Angstrom Resolution Cryo-Electron Microscopy Structure and Antigenic Sites of Coxsackievirus A6-Like Particles.J Virol2018
30479350Architecture and subunit arrangement of the complete Saccharomyces cerevisiae COMPASS complex.Sci Rep2018
29403048Development of a yeast internal-subunit eGFP labeling strategy and its application in subunit identification in eukaryotic group II chaperonin TRiC/CCT.Sci Rep2018
29625202Yeast Inner-Subunit PA-NZ-1 Labeling Strategy for Accurate Subunit Identification in a Macromolecular Complex through Cryo-EM Analysis.J Mol Biol2018
28880864Identification of an allosteric network that influences assembly and function of group II chaperonins.Nat Struct Mol Biol2017
28106073High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx.Cell Res2017
28148783Beta-Propiolactone Inactivation of Coxsackievirus A16 Induces Structural Alteration and Surface Modification of Viral Capsids.J Virol2017
29070691Structure, Immunogenicity, and Protective Mechanism of an Engineered Enterovirus 71-Like Particle Vaccine Mimicking 80S Empty Capsid.J Virol2017
26938634Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody.PLoS Pathog2016
27881601Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5.Genes Dev2016
27669901Leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) forms a Ca<sup>2+</sup>/H<sup>+</sup> antiporter.Sci Rep2016
27775711Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.Nat Struct Mol Biol2016
27135929Architecture of the mitochondrial calcium uniporter.Nature2016
25383530Structural insight into autoinhibition and histone H3-induced activation of DNMT3A.Nature2015
26073329High yield and efficient expression and purification of the human 5-HT3A receptor.Acta Pharmacol Sin2015
26073323Crystallization scale purification of α7 nicotinic acetylcholine receptor from mammalian cells using a BacMam expression system.Acta Pharmacol Sin2015
25515069Mitochondrial mutations associated with aminoglycoside ototoxicity and hearing loss susceptibility identified by meta-analysis.J Med Genet2015
24131712Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms.J Virol2014
23264040Structural and biochemical studies of RIG-I antiviral signaling.Protein Cell2013
23853712TRiC's tricks inhibit huntingtin aggregation.Elife2013
23541894Cryo-EM structure of a molluscan hemocyanin suggests its allosteric mechanism.Structure2013
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Co-authored papers 3
Old Dominion University
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Co-authored papers 2
Purdue University. Electronic address: .
Co-authored papers 2
University of Rochester
Co-authored papers 2
Institute of Biological Information Processing (Structural Biochemistry)
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ETH Zurich
Co-authored papers 1
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
Lawrence Berkeley National Laboratory, Joint BioEnergy Institute
Co-authored papers 1
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Co-authored papers 1
University of Oklahoma
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