Author details

Full Name

Kevin P Campbell

Affiliation

ORCID

Career Start Year

1975

Papers

444

H Index

126

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36723429	N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on Î±-dystroglycan and prevents muscular dystrophy.		2023
37753476	Identification of Matriglycan by Dual Exoglycosidase Digestion of Î±-Dystroglycan.		2023
37873263	Deep Mutational Scanning in Disease-related Genes with Saturation Mutagenesis-Reinforced Functional Assays (SMuRF).		2023
35613260	gene transfer in older mice with severe muscular dystrophy restores muscle function and greatly improves survival.	Science advances	2022
35750689	Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function.	Nat Commun	2022
34654610	Muscular dystrophy-dystroglycanopathy in a family of Labrador retrievers with a LARGE1 mutation.	Neuromuscular Disorders	2021
34578260	Lassa Fever Virus Binds Matriglycan-A Polymer of Alternating Xylose and Glucuronate-On Î±-Dystroglycan.	Viruses	2021
32620803	Investigations of an inducible intact dystrophin gene excision system in cardiac and skeletal muscle in vivo.	Scientific Reports	2020
32149355	HNK-1 sulfotransferase modulates Î±-dystroglycan glycosylation by 3-O-sulfation of glucuronic acid on matriglycan.	Glycobiology	2020
32975514	POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan.	Elife	2020
31097590	Protective role for the N-terminal domain of Î±-dystroglycan in Influenza A virus proliferation.	Proceedings of the National Academy of Sciences of the United States of America	2019
30914516	Dynamic Dystroglycan Complexes Mediate Cell Entry of Lassa Virus.	mBio	2019
31463571	The dystroglycan receptor maintains glioma stem cells in the vascular niche.	Acta Neuropathol	2019
31427525	A unique variant of lymphocytic choriomeningitis virus that induces pheromone binding protein MUP: Critical role for CTL.	Proceedings of the National Academy of Sciences of the United States of America	2019
31054580	Exogenous expression of the glycosyltransferase LARGE1 restores Î±-dystroglycan matriglycan and laminin binding in rhabdomyosarcoma.	Skelet Muscle	2019
30990900	Clinical utility of RNA sequencing to resolve unusual GNE myopathy with a novel promoter deletion.	Muscle and Nerve	2019
29759639	Uniparental disomy unveils a novel recessive mutation in POMT2.	Neuromuscul Disord	2018
30153853	Biochemical and pathological changes result from mutated Caveolin-3 in muscle.	Skelet Muscle	2018
28697784	Exome sequencing reveals independent SGCD deletions causing limb girdle muscular dystrophy in Boston terriers.	Skeletal Muscle	2017
28760865	Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development.	Journal of Neuroscience	2017
27773428	Biallelic Mutations in TMTC3, Encoding a Transmembrane and TPR-Containing Protein, Lead to Cobblestone Lissencephaly.	Am J Hum Genet	2016
27099343	Molecular Signatures of Membrane Protein Complexes Underlying Muscular Dystrophy.	Molecular and Cellular Proteomics	2016
26829621	Training the next generation of biomedical investigators in glycosciences.	J Clin Invest	2016
27130732	The functional O-mannose glycan on Î±-dystroglycan contains a phospho-ribitol primed for matriglycan addition.	Elife	2016
26908621	Collagen VI deficiency reduces muscle pathology, but does not improve muscle function, in the Î³-sarcoglycan-null mouse.	Human Molecular Genetics	2016
27707967	Neuronal Dystroglycan Is Necessary for Formation and Maintenance of Functional CCK-Positive Basket Cell Terminals on Pyramidal Cells.	Journal of Neuroscience	2016
27526028	Structural basis of laminin binding to the LARGE glycans on dystroglycan.	Nature Chemical Biology	2016
27879205	Structure of protein O-mannose kinase reveals a unique active site architecture.	Elife	2016
27625424	Role of dystroglycan in limiting contraction-induced injury to the sarcomeric cytoskeleton of mature skeletal muscle.	Proceedings of the National Academy of Sciences of the United States of America	2016
27496765	LARGE2-dependent glycosylation confers laminin-binding ability on proteoglycans.	Glycobiology	2016
26464793	Genetic characterization and improved genotyping of the dysferlin-deficient mouse strain Dysf (tm1Kcam).	Skeletal Muscle	2015
25882296	Matriglycan: a novel polysaccharide that links dystroglycan to the basement membrane.	Glycobiology	2015
26310427	GMPPB-Associated Dystroglycanopathy: Emerging Common Variants with Phenotype Correlation.	Human Mutation	2015
24778262	Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.	Proceedings of the National Academy of Sciences of the United States of America	2014
25279699	The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated Î±-dystroglycan functional glycosylation.	eLife	2014
24456943	Skeletal muscle's 3rd year anniversary.	Skeletal Muscle	2014
24397416	Third International Workshop for Glycosylation Defects in Muscular Dystrophies, 18-19 April 2013, Charlotte, USA.	Brain Pathology	2014
24491487	A novel missense mutation in POMT1 modulates the severe congenital muscular dystrophy phenotype associated with POMT1 nonsense mutations.	Neuromuscul Disord	2014
25138275	Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of Î±-dystroglycan in cells and tissues.	Journal of Biological Chemistry	2014
23288328	ISPD gene mutations are a common cause of congenital and limb-girdle muscular dystrophies.	Brain	2013
23768512	Mutations in GDP-mannose pyrophosphorylase B cause congenital and limb-girdle muscular dystrophies associated with hypoglycosylation of Î±-dystroglycan.	Am J Hum Genet	2013
23856421	Congenital disorder of glycosylation due to DPM1 mutations presenting with dystroglycanopathy-type congenital muscular dystrophy.	Molecular Genetics and Metabolism	2013
24252195	Glial scaffold required for cerebellar granule cell migration is dependent on dystroglycan function as a receptor for basement membrane proteins.	Acta Neuropathol Commun	2013
23929950	SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function.	Science	2013
24132234	LARGE glycans on dystroglycan function as a tunable matrix scaffold to prevent dystrophy.	Nature	2013
24175977	MG53's new identity.	Skeletal Muscle	2013
23279385	Cell entry of Lassa virus induces tyrosine phosphorylation of dystroglycan.	Cellular Microbiology	2013
23223448	Loss of LARGE2 disrupts functional glycosylation of Î±-dystroglycan in prostate cancer.	Journal of Biological Chemistry	2013
23619358	Illuminating regeneration: noninvasive imaging of disease progression in muscular dystrophy.	Journal of Clinical Investigation	2013
23125099	Xylosyl- and glucuronyltransferase functions of LARGE in Î±-dystroglycan modification are conserved in LARGE2.	Glycobiology	2013