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Author Details
Full Name
Alessandro Ori
Affiliation
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)
ORCID
Career Start Year
2007
Papers
82
H Index
35
Expertise
CM4AI Collaborator
Emma Lundberg (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36747793
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
bioRxiv
2023
37630850
Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice.
Nutrients
2023
37318382
Membrane shapers from two distinct superfamilies cooperate in the development of neuronal morphology.
J Cell Biol
2023
37101405
Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.
Aging Cell
2023
34695195
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Blood
2022
35767948
Inflammaging is driven by upregulation of innate immune receptors and systemic interferon signaling and is ameliorated by dietary restriction.
Cell Rep
2022
35594347
Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration.
Sci Adv
2022
35513564
The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2.
Oncogene
2022
36179048
Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics.
Proc Natl Acad Sci U S A
2022
36131016
CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.
Nature
2022
35053391
Multifaceted Microcephaly-Related Gene MCPH1.
Cells
2022
35194998
Glycation Alters the Fatty Acid Binding Capacity of Human Serum Albumin.
J Agric Food Chem
2022
35165416
Metabolic determination of cell fate through selective inheritance of mitochondria.
Nat Cell Biol
2022
34368155
The Hematopoietic Bone Marrow Niche Ecosystem.
Front Cell Dev Biol
2021
33542216
The N-terminal BRCT domain determines MCPH1 function in brain development and fertility.
Cell Death Dis
2021
33594975
HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.
Elife
2021
33755596
GMPPA defects cause a neuromuscular disorder with α-dystroglycan hyperglycosylation.
J Clin Invest
2021
33855766
Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice.
FASEB J
2021
34516047
Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses.
Curr Protoc
2021
34683917
Iron Oxide Nanoparticles Carrying 5-Fluorouracil in Combination with Magnetic Hyperthermia Induce Thrombogenic Collagen Fibers, Cellular Stress, and Immune Responses in Heterotopic Human Colon Cancer in Mice.
Pharmaceutics
2021
34795246
Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation.
Nat Commun
2021
34107247
Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality.
Cell Rep
2021
34210973
ATR regulates neuronal activity by modulating presynaptic firing.
Nat Commun
2021
32558274
Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation.
Mol Syst Biol
2020
31795790
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
Autophagy
2020
33139960
Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegans.
Nat Metab
2020
32807790
Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.
Nat Commun
2020
32574648
Stem cell aging: The upcoming era of proteins and metabolites.
Mech Ageing Dev
2020
32737464
Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry.
Nat Protoc
2020
32348758
Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction.
Cell Rep
2020
30530755
Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
J Exp Med
2019
31817246
Increased Expression of Immature Mannose-Containing Glycoproteins and Sialic Acid in Aged Mouse Brains.
Int J Mol Sci
2019
31783876
Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer.
Cell Commun Signal
2019
31719688
Author Correction: Metastatic-niche labelling reveals parenchymal cells with stem features.
Nature
2019
31733513
Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines.
iScience
2019
31503451
Quantitation of Reactive Acyl-CoA Species Mediated Protein Acylation by HPLC-MS/MS.
Anal Chem
2019
31462798
Metastatic-niche labelling reveals parenchymal cells with stem features.
Nature
2019
30886199
Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p.
Sci Rep
2019
31089132
Nucleoporin Nup155 is part of the p53 network in liver cancer.
Nat Commun
2019
31031010
Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals.
Cell
2019
30726097
Comparison of Protein Quantification in a Complex Background by DIA and TMT Workflows with Fixed Instrument Time.
J Proteome Res
2019
29700228
NUFIP1 is a ribosome receptor for starvation-induced ribophagy.
Science
2018
30082728
TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells.
Nat Commun
2018
29967062
Quantifying compartment-associated variations of protein abundance in proteomics data.
Mol Syst Biol
2018
29858605
Cellular and epigenetic drivers of stem cell ageing.
Nat Rev Mol Cell Biol
2018
30209298
Author Correction: TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells.
Nat Commun
2018
30068331
Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging.
BMC Biol
2018
29363612
Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC).
Mol Cell Proteomics
2018
27939741
Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.
Am J Pathol
2017
29254951
Landscape of nuclear transport receptor cargo specificity.
Mol Syst Biol
2017
1 - 50 of 82
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