| 37098914 | Pharmacokinetic Model of Tenofovir and Emtricitabine and Their Intracellular Metabolites in Patients in the ANRS 134-COPHAR 3 Trial Using Dose Records. | Antimicrob Agents Chemother | 2023 |
| 37632446 | Proteolytically Stable Diaza-Peptide Foldamers Mimic Helical Hot Spots of Protein-Protein Interactions and Act as Natural Chaperones. | J Med Chem | 2023 |
| 35235336 | Biological Investigation of a Water-Soluble Isoginkgetin-Phosphate Analogue, Targeting the Spliceosome with <i>In Vivo</i> Antitumor Activity. | J Med Chem | 2022 |
| 35394133 | Evaluation of a six-probe cocktail (caffeine, tolbutamide, omeprazole, dextromethorphan, midazolam, and digoxin) approach to estimate hepatic drug detoxification capability and dosage requirements after a single oral dosing in healthy Chinese volunteers. | Naunyn Schmiedebergs Arch Pharmacol | 2022 |
| 36498939 | In Vivo Sustained Release of the Retrograde Transport Inhibitor Retro-2.1 Formulated in a Thermosensitive Hydrogel. | Int J Mol Sci | 2022 |
| 35906245 | TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway. | Nat Commun | 2022 |
| 34212184 | An adamantamine derivative as a drug candidate for the treatment of visceral leishmaniasis. | J Antimicrob Chemother | 2021 |
| 35485334 | Comparison of three galenic forms of lamivudine in young West African children living with Human Immunodeficiency Virus. | Antivir Ther | 2021 |
| 33603137 | Pharmacokinetic neuroimaging to study the dose-related brain kinetics and target engagement of buprenorphine in vivo. | Neuropsychopharmacology | 2021 |
| 33851217 | In the mouse, prostaglandin D2 signalling protects the endometrium against adenomyosis. | Mol Hum Reprod | 2021 |
| 33862516 | Azetidinimines as a novel series of non-covalent broad-spectrum inhibitors of β-lactamases with submicromolar activities against carbapenemases KPC-2 (class A), NDM-1 (class B) and OXA-48 (class D). | Eur J Med Chem | 2021 |
| 34907230 | Circadian and chemotherapy-related changes in urinary modified nucleosides excretion in patients with metastatic colorectal cancer. | Sci Rep | 2021 |
| 32130882 | Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease. | Cell Metab | 2020 |
| 31853544 | Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites. | Nucleic Acids Res | 2020 |
| 33311466 | Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system. | Nat Commun | 2020 |
| 33052234 | A snake toxin as a theranostic agent for the type 2 vasopressin receptor. | Theranostics | 2020 |
| 32826232 | The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies. | Cancer Discov | 2020 |
| 30521097 | Orchestration of Tryptophan-Kynurenine Pathway, Acute Decompensation, and Acute-on-Chronic Liver Failure in Cirrhosis. | Hepatology | 2019 |
| 31690750 | Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model. | Sci Rep | 2019 |
| 29979629 | Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen. | FASEB J | 2019 |
| 31428698 | In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. | Commun Biol | 2019 |
| 31038003 | Dodecyl creatine ester-loaded nanoemulsion as a promising therapy for creatine transporter deficiency. | Nanomedicine (Lond) | 2019 |
| 30846549 | Microenvironment tailors nTreg structure and function. | Proc Natl Acad Sci U S A | 2019 |
| 29202409 | A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation. | Eur J Med Chem | 2018 |
| 29936438 | Methotrexate and BAFF interaction prevents immunization against TNF inhibitors. | Ann Rheum Dis | 2018 |
| 29553486 | The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques. | J Clin Invest | 2018 |
| 27941394 | Virological efficacy of 24-week fozivudine-based regimen in ART-naive patients from Tanzania and Côte d'Ivoire. | AIDS | 2017 |
| 28578404 | A simple and rapid LC-MS/MS method for therapeutic drug monitoring of cetuximab: a GPCO-UNICANCER proof of concept study in head-and-neck cancer patients. | Sci Rep | 2017 |
| 26787703 | Activity of Bisnaphthalimidopropyl Derivatives against Trypanosoma brucei. | Antimicrob Agents Chemother | 2016 |
| 26490357 | A limited sampling strategy based on maximum a posteriori Bayesian estimation for a five-probe phenotyping cocktail. | Eur J Clin Pharmacol | 2016 |
| 27482103 | Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy. | Proc Natl Acad Sci U S A | 2016 |
| 25833047 | Detection of Simian Immunodeficiency Virus in Semen, Urethra, and Male Reproductive Organs during Efficient Highly Active Antiretroviral Therapy. | J Virol | 2015 |
| 24555414 | Therapeutic modalities of squalenoyl nanocomposites in colon cancer: an ongoing search for improved efficacy. | ACS Nano | 2014 |
| 25383741 | An optimal LC-MS/MS method for determination of azithromycin in white blood cells: application to pediatric samples. | Bioanalysis | 2014 |
| 24862093 | Pre-clinical development of a combination microbicide vaginal ring containing dapivirine and darunavir. | J Antimicrob Chemother | 2014 |
| 23840581 | Polymorphisms of Pyrimidine Pathway Enzymes Encoding Genes and HLA-B*40â¿¶01 Carriage in Stavudine-Associated Lipodystrophy in HIV-Infected Patients. | PLoS One | 2013 |
| 21282454 | Association of thymidylate synthase gene polymorphisms with stavudine triphosphate intracellular levels and lipodystrophy. | Antimicrob Agents Chemother | 2011 |
| 21438632 | In vitro primary human and animal cell-based blood-brain barrier models as a screening tool in drug discovery. | Mol Pharm | 2011 |
| 21464249 | Plasma and intracellular tenofovir pharmacokinetics in the neonate (ANRS 12109 trial, step 2). | Antimicrob Agents Chemother | 2011 |
| 21464241 | Very high concentrations of active intracellular phosphorylated emtricitabine in neonates (ANRS 12109 trial, step 2). | Antimicrob Agents Chemother | 2011 |
| 21173182 | Concentrations of tenofovir and emtricitabine in breast milk of HIV-1-infected women in Abidjan, Cote d'Ivoire, in the ANRS 12109 TEmAA Study, Step 2. | Antimicrob Agents Chemother | 2011 |
| 20192724 | Relationship between HIV/Highly active antiretroviral therapy (HAART)-associated lipodystrophy syndrome and stavudine-triphosphate intracellular levels in patients with stavudine-based antiretroviral regimens. | Clin Infect Dis | 2010 |
| 21083268 | Drug bioanalysis and biomarker discovery at the Commissariat à l'énergie atomique et aux énergies alternatives. | Bioanalysis | 2010 |
| 19264560 | Direct analysis of valsartan or candesartan in human plasma and urines by on-line solid phase extraction coupled to electrospray tandem mass spectrometry. | J Chromatogr B Analyt Technol Biomed Life Sci | 2009 |
| 19075072 | Combination of tenofovir and emtricitabine plus efavirenz: in vitro modulation of ABC transporter and intracellular drug accumulation. | Antimicrob Agents Chemother | 2009 |
| 19273671 | Pilot pharmacokinetic study of human immunodeficiency virus-infected patients receiving tenofovir disoproxil fumarate (TDF): investigation of systemic and intracellular interactions between TDF and abacavir, lamivudine, or lopinavir-ritonavir. | Antimicrob Agents Chemother | 2009 |
| 18097680 | Biological monitoring of occupational exposure to di(2-ethylhexyl) phthalate: survey of workers exposed to plastisols. | Int Arch Occup Environ Health | 2008 |
| 18692133 | Emtricitabine: Inhibitor and substrate of multidrug resistance associated protein. | Eur J Pharm Sci | 2008 |
| 18426897 | High levels of zidovudine (AZT) and its intracellular phosphate metabolites in AZT- and AZT-lamivudine-treated newborns of human immunodeficiency virus-infected mothers. | Antimicrob Agents Chemother | 2008 |
| 17935070 | Specificity enhancement with LC-positive ESI-MS/MS for the measurement of nucleotides: application to the quantitative determination of carbovir triphosphate, lamivudine triphosphate and tenofovir diphosphate in human peripheral blood mononuclear cells. | J Mass Spectrom | 2008 |