Skip to Main Content

Author Details

Alain Pruvost
Universite Paris Saclay
1994
75
28
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37098914Pharmacokinetic Model of Tenofovir and Emtricitabine and Their Intracellular Metabolites in Patients in the ANRS 134-COPHAR 3 Trial Using Dose Records.Antimicrob Agents Chemother2023
37632446Proteolytically Stable Diaza-Peptide Foldamers Mimic Helical Hot Spots of Protein-Protein Interactions and Act as Natural Chaperones.J Med Chem2023
35235336Biological Investigation of a Water-Soluble Isoginkgetin-Phosphate Analogue, Targeting the Spliceosome with <i>In Vivo</i> Antitumor Activity.J Med Chem2022
35394133Evaluation of a six-probe cocktail (caffeine, tolbutamide, omeprazole, dextromethorphan, midazolam, and digoxin) approach to estimate hepatic drug detoxification capability and dosage requirements after a single oral dosing in healthy Chinese volunteers.Naunyn Schmiedebergs Arch Pharmacol2022
36498939In Vivo Sustained Release of the Retrograde Transport Inhibitor Retro-2.1 Formulated in a Thermosensitive Hydrogel.Int J Mol Sci2022
35906245TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.Nat Commun2022
34212184An adamantamine derivative as a drug candidate for the treatment of visceral leishmaniasis.J Antimicrob Chemother2021
35485334Comparison of three galenic forms of lamivudine in young West African children living with Human Immunodeficiency Virus.Antivir Ther2021
33603137Pharmacokinetic neuroimaging to study the dose-related brain kinetics and target engagement of buprenorphine in vivo.Neuropsychopharmacology2021
33851217In the mouse, prostaglandin D2 signalling protects the endometrium against adenomyosis.Mol Hum Reprod2021
33862516Azetidinimines as a novel series of non-covalent broad-spectrum inhibitors of β-lactamases with submicromolar activities against carbapenemases KPC-2 (class A), NDM-1 (class B) and OXA-48 (class D).Eur J Med Chem2021
34907230Circadian and chemotherapy-related changes in urinary modified nucleosides excretion in patients with metastatic colorectal cancer.Sci Rep2021
32130882Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease.Cell Metab2020
31853544Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.Nucleic Acids Res2020
33311466Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system.Nat Commun2020
33052234A snake toxin as a theranostic agent for the type 2 vasopressin receptor.Theranostics2020
32826232The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.Cancer Discov2020
30521097Orchestration of Tryptophan-Kynurenine Pathway, Acute Decompensation, and Acute-on-Chronic Liver Failure in Cirrhosis.Hepatology2019
31690750Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model.Sci Rep2019
29979629Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen.FASEB J2019
31428698In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice.Commun Biol2019
31038003Dodecyl creatine ester-loaded nanoemulsion as a promising therapy for creatine transporter deficiency.Nanomedicine (Lond)2019
30846549Microenvironment tailors nTreg structure and function.Proc Natl Acad Sci U S A2019
29202409A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation.Eur J Med Chem2018
29936438Methotrexate and BAFF interaction prevents immunization against TNF inhibitors.Ann Rheum Dis2018
29553486The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques.J Clin Invest2018
27941394Virological efficacy of 24-week fozivudine-based regimen in ART-naive patients from Tanzania and Côte d'Ivoire.AIDS2017
28578404A simple and rapid LC-MS/MS method for therapeutic drug monitoring of cetuximab: a GPCO-UNICANCER proof of concept study in head-and-neck cancer patients.Sci Rep2017
26787703Activity of Bisnaphthalimidopropyl Derivatives against Trypanosoma brucei.Antimicrob Agents Chemother2016
26490357A limited sampling strategy based on maximum a posteriori Bayesian estimation for a five-probe phenotyping cocktail.Eur J Clin Pharmacol2016
27482103Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy.Proc Natl Acad Sci U S A2016
25833047Detection of Simian Immunodeficiency Virus in Semen, Urethra, and Male Reproductive Organs during Efficient Highly Active Antiretroviral Therapy.J Virol2015
24555414Therapeutic modalities of squalenoyl nanocomposites in colon cancer: an ongoing search for improved efficacy.ACS Nano2014
25383741An optimal LC-MS/MS method for determination of azithromycin in white blood cells: application to pediatric samples.Bioanalysis2014
24862093Pre-clinical development of a combination microbicide vaginal ring containing dapivirine and darunavir.J Antimicrob Chemother2014
23840581Polymorphisms of Pyrimidine Pathway Enzymes Encoding Genes and HLA-B*40â¿¶01 Carriage in Stavudine-Associated Lipodystrophy in HIV-Infected Patients.PLoS One2013
21282454Association of thymidylate synthase gene polymorphisms with stavudine triphosphate intracellular levels and lipodystrophy.Antimicrob Agents Chemother2011
21438632In vitro primary human and animal cell-based blood-brain barrier models as a screening tool in drug discovery.Mol Pharm2011
21464249Plasma and intracellular tenofovir pharmacokinetics in the neonate (ANRS 12109 trial, step 2).Antimicrob Agents Chemother2011
21464241Very high concentrations of active intracellular phosphorylated emtricitabine in neonates (ANRS 12109 trial, step 2).Antimicrob Agents Chemother2011
21173182Concentrations of tenofovir and emtricitabine in breast milk of HIV-1-infected women in Abidjan, Cote d'Ivoire, in the ANRS 12109 TEmAA Study, Step 2.Antimicrob Agents Chemother2011
20192724Relationship between HIV/Highly active antiretroviral therapy (HAART)-associated lipodystrophy syndrome and stavudine-triphosphate intracellular levels in patients with stavudine-based antiretroviral regimens.Clin Infect Dis2010
21083268Drug bioanalysis and biomarker discovery at the Commissariat à l'énergie atomique et aux énergies alternatives.Bioanalysis2010
19264560Direct analysis of valsartan or candesartan in human plasma and urines by on-line solid phase extraction coupled to electrospray tandem mass spectrometry.J Chromatogr B Analyt Technol Biomed Life Sci2009
19075072Combination of tenofovir and emtricitabine plus efavirenz: in vitro modulation of ABC transporter and intracellular drug accumulation.Antimicrob Agents Chemother2009
19273671Pilot pharmacokinetic study of human immunodeficiency virus-infected patients receiving tenofovir disoproxil fumarate (TDF): investigation of systemic and intracellular interactions between TDF and abacavir, lamivudine, or lopinavir-ritonavir.Antimicrob Agents Chemother2009
18097680Biological monitoring of occupational exposure to di(2-ethylhexyl) phthalate: survey of workers exposed to plastisols.Int Arch Occup Environ Health2008
18692133Emtricitabine: Inhibitor and substrate of multidrug resistance associated protein.Eur J Pharm Sci2008
18426897High levels of zidovudine (AZT) and its intracellular phosphate metabolites in AZT- and AZT-lamivudine-treated newborns of human immunodeficiency virus-infected mothers.Antimicrob Agents Chemother2008
17935070Specificity enhancement with LC-positive ESI-MS/MS for the measurement of nucleotides: application to the quantitative determination of carbovir triphosphate, lamivudine triphosphate and tenofovir diphosphate in human peripheral blood mononuclear cells.J Mass Spectrom2008
  • 1 - 50 of 75

Recommended Authors

Chulalongkorn University
Career Start Year 2013
Number of shared co-authors 0
Federal Institute for Drugs and Medical Devices (BfArM)
Career Start Year 2008
Number of shared co-authors 0
Nationwide Children's Hospital, College of Medicine, The Ohio State University
Career Start Year 2008
Number of shared co-authors 0
University of California San Francisco
Career Start Year 2006
Number of shared co-authors 0
Unit for Pharmacokinetics and Drug Metabolism, University of Gothenburg
Career Start Year 2005
Number of shared co-authors 0
Collegeville
Career Start Year 2004
Number of shared co-authors 0
Genentech Inc.
Career Start Year 2003
Number of shared co-authors 0
Clinical Development
Career Start Year 2003
Number of shared co-authors 2
Schulich School of Medicine and Dentistry, Western University
Career Start Year 2003
Number of shared co-authors 0
Seoul National University Bundang Hospital and College of Medicine
Career Start Year 2002
Number of shared co-authors 0
Clinical Development
Career Start Year 1998
Number of shared co-authors 2
Oncology R&D
Career Start Year 1998
Number of shared co-authors 0
Perelman School of Medicine, University of Pennsylvania
Career Start Year 1998
Number of shared co-authors 0
and of Biochemistry and Pharmacy, University of Tuebingen
Career Start Year 1996
Number of shared co-authors 0
Faculty of Pharmacy, Suez Canal University
Career Start Year 1995
Number of shared co-authors 0
University of Louisville
Career Start Year 1991
Number of shared co-authors 0
University of Toronto
Career Start Year 1990
Number of shared co-authors 0
University Medical Center Hamburg-Eppendorf
Career Start Year 1989
Number of shared co-authors 0
Departamento de Toxicologia y Farmacologia Preclinica
Career Start Year 1989
Number of shared co-authors 2
Novartis
Career Start Year 1988
Number of shared co-authors 0
Vanderbilt University Medical Center
Career Start Year 1988
Number of shared co-authors 0
university of california san diego Health, Center for Advanced Laboratory Medicine
Career Start Year 1988
Number of shared co-authors 0
Department of Pharmaceutical Sciences, Utrecht University
Career Start Year 1987
Number of shared co-authors 0
University of Kansas Medical Center
Career Start Year 1985
Number of shared co-authors 0
ReNeuroGen LLC
Career Start Year 1985
Number of shared co-authors 0
Cincinnati Children's Hospital Medical Center
Career Start Year 1982
Number of shared co-authors 0
Department of Pharmaceutics, University of Florida
Career Start Year 1979
Number of shared co-authors 0
University of Miami, Miller School of Medicine
Career Start Year 1977
Number of shared co-authors 1
Perelman School of Medicine, University of Pennsylvania
Career Start Year 1968
Number of shared co-authors 0
College of Medicine, The Ohio State University
Career Start Year 1967
Number of shared co-authors 0

Collaborators

IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 3
Universite Paris-Saclay
Co-authored papers 2
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 1
Duke University
Co-authored papers 1
The Francis Crick Institute
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Universite Paris Cite, INSERM, CNRS
Co-authored papers 1
Lille University Hospital, INSERM UMR-S7, CNRS UMR9020, Lille University.
Co-authored papers 1
INSERM, France Villejuif Universite Paris-Saclay
Co-authored papers 1
Dana-Farber Cancer Institute
Co-authored papers 1
Universite de Paris, Inserm CIC 1427
Co-authored papers 1
INSERM UMR , St Louis Hospital, University of Paris
Co-authored papers 1
Co-authored papers 1
Universite Paris Cite, INSERM, CNRS
Co-authored papers 1
Universite Paris Cite, INSERM, CNRS
Co-authored papers 1
INSERM UMR , St Louis Hospital, University of Paris
Co-authored papers 1
Dana-Farber Cancer Institute
Co-authored papers 1
Duke University
Co-authored papers 1
Universite de Paris, U1 INSERM
Co-authored papers 1
University of Parma
Co-authored papers 1
Dana Farber Cancer Institute
Co-authored papers 1
Duke University School of Medicine Durham
Co-authored papers 1
Hospital Germans Trias i Pujol
Co-authored papers 1
INSERM UMR , St Louis Hospital, University of Paris
Co-authored papers 1
Lyon Neuroscience Research Center, University of Lyon, CNRS UMR2, Inserm U1028
Co-authored papers 1
INSERM U1170, Universite Paris Saclay
Co-authored papers 1
Universite Paris Cite, INSERM, CNRS
Co-authored papers 1
Hopital Universitaire Necker-Enfants Malades, Assistance Publique - Hopitaux de Paris
Co-authored papers 1
INSERM UMR , St Louis Hospital, University of Paris
Co-authored papers 1
Ben-Gurion University of the Negev
Co-authored papers 1