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Author Details

Florian Beck
Max Planck Institute of Biochemistry
2005
48
29
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37613825Towards the Visual Proteomics of C. reinhardtii using High-throughput Collaborative in situ Cryo-ET.Microsc Microanal2023
36122245In situ structural analysis reveals membrane shape transitions during autophagosome formation.Proc Natl Acad Sci U S A2022
35346811A feature-guided, focused 3D signal permutation method for subtomogram averaging.J Struct Biol2022
35811088A transformation clustering algorithm and its application in polyribosomes structural profiling.Nucleic Acids Res2022
36042418Volumetric macromolecule identification in cryo-electron tomograms using capsule networks.BMC Bioinformatics2022
33039147High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2.Biochem Biophys Res Commun2021
34403403In Response.Anesth Analg2021
34508074In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli.Nat Commun2021
34089875Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex.J Struct Biol2021
32647264Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS.Sci Rep2020
31882451Direct visualization of degradation microcompartments at the ER membrane.Proc Natl Acad Sci U S A2020
30559193Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle.Proc Natl Acad Sci U S A2019
31230946The Architecture of Traveling Actin Waves Revealed by Cryo-Electron Tomography.Structure2019
30962530Biogenic regions of cyanobacterial thylakoids form contact sites with the plasma membrane.Nat Plants2019
29398115In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.Cell2018
30067984Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.Cell Rep2018
30301811Combined inhibition of receptor tyrosine and p21-activated kinases as a therapeutic strategy in childhood ALL.Blood Adv2018
28060719Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition.Blood2017
28292943Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.Mol Cell Proteomics2017
28396430In situ structural studies of tripeptidyl peptidase II (TPPII) reveal spatial association with proteasomes.Proc Natl Acad Sci U S A2017
28115689Structural insights into the functional cycle of the ATPase module of the 26S proteasome.Proc Natl Acad Sci U S A2017
29229809Proteasomes tether to two distinct sites at the nuclear pore complex.Proc Natl Acad Sci U S A2017
26849035Nucleotide-dependent conformational changes of the AAA+ ATPase p97 revisited.FEBS Lett2016
27342858Structure of the human 26S proteasome at a resolution of 3.9 ÿ.Proc Natl Acad Sci U S A2016
25613890Proteasomes. A molecular census of 26S proteasomes in intact neurons.Science2015
26130806Structural characterization of the interaction of Ubp6 with the 26S proteasome.Proc Natl Acad Sci U S A2015
24324209Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways.Blood2014
24706844Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome.Proc Natl Acad Sci U S A2014
23322602Deciphering of ADP-induced, phosphotyrosine-dependent signaling networks in human platelets by Src-homology 2 region (SH2)-profiling.Proteomics2013
23643786Localization of the regulatory particle subunit Sem1 in the 26S proteasome.Biochem Biophys Res Commun2013
23589842Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation.Proc Natl Acad Sci U S A2013
23201114Developmental changes of the protein repertoire in the rat auditory brainstem: a comparative proteomics approach in the superior olivary complex and the inferior colliculus with DIGE and iTRAQ.J Proteomics2013
23307401D-score: a search engine independent MD-score.Proteomics2013
22215586Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy.Proc Natl Acad Sci U S A2012
22927375Near-atomic resolution structural model of the yeast 26S proteasome.Proc Natl Acad Sci U S A2012
22665297Robust workflow for iTRAQ-based peptide and protein quantification.Methods Mol Biol2012
22307589Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach.Proc Natl Acad Sci U S A2012
20719249Maximum likelihood based classification of electron tomographic data.J Struct Biol2011
21704708Computer controlled cryo-electron microscopy--TOM² a software package for high-throughput applications.J Struct Biol2011
21298789The good, the bad, the ugly: validating the mass spectrometric analysis of modified peptides.Proteomics2011
21098295Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution.Proc Natl Acad Sci U S A2010
19581588Insights into the molecular architecture of the 26S proteasome.Proc Natl Acad Sci U S A2009
19653995An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome.Biochem Biophys Res Commun2009
17151018Proteomics analysis of Thermoplasma acidophilum with a focus on protein complexes.Mol Cell Proteomics2007
17531228Automated cryoelectron microscopy of "single particles" applied to the 26S proteasome.FEBS Lett2007
17884579Correlative microscopy: bridging the gap between fluorescence light microscopy and cryo-electron tomography.J Struct Biol2007
17173858Structural analysis of the 26S proteasome by cryoelectron tomography.Biochem Biophys Res Commun2007
15721576TOM software toolbox: acquisition and analysis for electron tomography.J Struct Biol2005
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Collaborators

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Co-authored papers 18
Utrecht University
Co-authored papers 15
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Co-authored papers 11
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Co-authored papers 9
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Co-authored papers 7
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Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 3
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Co-authored papers 3
Co-authored papers 2
National Centre for Biotechnology (CNB CSIC), Campus Universidad Autonoma de Madrid
Co-authored papers 2
University of California San Diego, USA Howard Hughes Medical Institute
Co-authored papers 2
Institute for Computational Biology
Co-authored papers 2
Research Unit Analytical Pathology, German Research Center for Environmental Health
Co-authored papers 2
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Co-authored papers 2
Medical Research Council Laboratory of Molecular Biology
Co-authored papers 2
Institute of Anatomy, University of Zurich
Co-authored papers 1
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Technical University of Munich.
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Schrodinger Inc.
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