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Author Details
Full Name
Craig N Kreklywich
Affiliation
Vaccine and Gene Therapy Institute, Oregon Health and Science University
ORCID
Career Start Year
1991
Papers
49
H Index
23
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37398229
The pentameric complex is not required for vertical transmission of cytomegalovirus in seronegative pregnant rhesus macaques.
bioRxiv
2023
37782657
Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation.
PLoS Pathog
2023
37983245
Mayaro virus pathogenesis and immunity in rhesus macaques.
PLoS Negl Trop Dis
2023
37923717
Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.
Nat Commun
2023
35788221
Development of a next-generation chikungunya virus vaccine based on the HydroVax platform.
PLoS Pathog
2022
33205500
Macrophage depletion of CMV latently infected donor hearts ameliorates recipient accelerated chronic rejection.
Transpl Infect Dis
2021
33601113
Rat and human cytomegalovirus ORF116 encodes a virion envelope glycoprotein required for infectivity.
Virology
2021
33793555
Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses.
PLoS Negl Trop Dis
2021
33835811
Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors.
J Med Chem
2021
33405337
Blocking the IL-1 receptor reduces cardiac transplant ischemia and reperfusion injury and mitigates CMV-accelerated chronic rejection.
Am J Transplant
2021
33228102
Rat Cytomegalovirus Virion-Associated Proteins R131 and R129 Are Necessary for Infection of Macrophages and Dendritic Cells.
Pathogens
2020
31935257
A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy.
PLoS One
2020
30917980
Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs.
Antimicrob Agents Chemother
2019
31736977
Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease.
Front Immunol
2019
31848362
Characterization of a live-attenuated HCMV-based vaccine platform.
Sci Rep
2019
31431555
Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34[+] Hematopoietic Progenitor Cells and Humanized NSG Mice.
mBio
2019
31316006
Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity.
Sci Transl Med
2019
29343712
Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology.
Nat Commun
2018
28628616
Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.
PLoS Negl Trop Dis
2017
28278237
Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.
PLoS Pathog
2017
28380070
Correction: Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.
PLoS Pathog
2017
28428537
Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice.
Sci Rep
2017
25766876
Rat Cytomegalovirus Vaccine Prevents Accelerated Chronic Rejection in CMV-Naïve Recipients of Infected Donor Allograft Hearts.
Am J Transplant
2015
24161922
HCMV infection of humanized mice after transplantation of G-CSF-mobilized peripheral blood stem cells from HCMV-seropositive donors.
Biol Blood Marrow Transplant
2014
24829346
Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes.
J Virol
2014
24639226
Fluorescence-based laser capture microscopy technology facilitates identification of critical in vivo cytomegalovirus transcriptional programs.
Methods Mol Biol
2014
24691437
Cytomegalovirus pp65 limits dissemination but is dispensable for persistence.
J Clin Invest
2014
23936572
Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity.
PLoS Negl Trop Dis
2013
22915808
Cytomegalovirus CC chemokine promotes immune cell migration.
J Virol
2012
20980502
Cytomegalovirus microRNA expression is tissue specific and is associated with persistence.
J Virol
2011
22241980
A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection.
PLoS Pathog
2011
22052378
Simian varicella virus gene expression during acute and latent infection of rhesus macaques.
J Neurovirol
2011
21199347
Cytomegalovirus latency promotes cardiac lymphoid neogenesis and accelerated allograft rejection in CMV naïve recipients.
Am J Transplant
2011
20930069
IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin.
Blood
2011
20833379
Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model.
Cell Host Microbe
2010
19349057
Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells.
Virology
2009
18093265
The role of angiogenic and wound repair factors during CMV-accelerated transplant vascular sclerosis in rat cardiac transplants.
Am J Transplant
2008
18448536
Human cytomegalovirus secretome contains factors that induce angiogenesis and wound healing.
J Virol
2008
17251289
Rat cytomegalovirus gene expression in cardiac allograft recipients is tissue specific and does not parallel the profiles detected in vitro.
J Virol
2007
17175227
Cytomegalovirus accelerates chronic allograft nephropathy in a rat renal transplant model with associated provocative chemokine profiles.
Transplant Proc
2006
15707397
Rat cytomegalovirus-accelerated transplant vascular sclerosis is reduced with mutation of the chemokine-receptor R33.
Am J Transplant
2005
16051870
Mouse cytomegalovirus M33 is necessary and sufficient in virus-induced vascular smooth muscle cell migration.
J Virol
2005
12525653
Cytomegalovirus-mediated upregulation of chemokine expression correlates with the acceleration of chronic rejection in rat heart transplants.
J Virol
2003
11907411
Elimination of donor-specific alloreactivity prevents cytomegalovirus-accelerated chronic rejection in rat small bowel and heart transplants.
Transplantation
2002
11267529
Kinetics and development of CMV-accelerated transplant vascular sclerosis in rat cardiac allografts is linked to early increase in chemokine expression and presence of virus.
Transplant Proc
2001
8508678
Linkage mapping detects two secondary microdeletions in cell hybrid HHW1064, used to isolate DNA probes from within 5q11.2-->q13.3.
Cytogenet Cell Genet
1993
1674144
A polymorphic DNA marker at the D8S131 locus.
Nucleic Acids Res
1991
1762937
Dinucleotide repeat polymorphism at the D5S260 locus on chromosome 5q.
Nucleic Acids Res
1991
1945862
Dinucleotide repeat polymorphisms at the D5S257 and D5S268 loci on chromosome 5p.
Nucleic Acids Res
1991
1 - 49 of 49
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row(s) 1 - 30 of 30
Collaborators
Daniel N Streblow
Vaccine and Gene Therapy Institute, Oregon Health and Science University
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Jay A Nelson
Oregon Health and Science University
Co-authored papers
18
Victor R DeFilippis
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Co-authored papers
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Patrizia Caposio
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Alec J Hirsch
Vaccine & Gene Therapy Institute, Oregon Health & Science University
Co-authored papers
6
Jessica L Smith
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Co-authored papers
5
Louis J Picker
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Thomas E Morrison
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Mark T Heise
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Co-authored papers
4
Lindsey B Crawford
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers
4
Michael S Diamond
Washington University School of Medicine
Co-authored papers
3
Devorah C Goldman
Oregon Health & Science University
Co-authored papers
3
William H Fleming
Oregon Health & Science University
Co-authored papers
3
Richard D Smith
Pacific Northwest National Laboratory
Co-authored papers
2
James E Crowe
Vanderbilt University Medical Center
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2
Timothy Alexander
Vaccine and Gene Therapy Institute, Oregon Health and Science University
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2
Finn Grey
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Andrew D Yurochko
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Christopher L Corless
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