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Author Details

Craig N Kreklywich
Vaccine and Gene Therapy Institute, Oregon Health and Science University
1991
49
23
PMIDPaper TitleJournal TitlePublished Year
37398229The pentameric complex is not required for vertical transmission of cytomegalovirus in seronegative pregnant rhesus macaques.bioRxiv2023
37782657Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation.PLoS Pathog2023
37983245Mayaro virus pathogenesis and immunity in rhesus macaques.PLoS Negl Trop Dis2023
37923717Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.Nat Commun2023
35788221Development of a next-generation chikungunya virus vaccine based on the HydroVax platform.PLoS Pathog2022
33205500Macrophage depletion of CMV latently infected donor hearts ameliorates recipient accelerated chronic rejection.Transpl Infect Dis2021
33601113Rat and human cytomegalovirus ORF116 encodes a virion envelope glycoprotein required for infectivity.Virology2021
33793555Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses.PLoS Negl Trop Dis2021
33835811Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors.J Med Chem2021
33405337Blocking the IL-1 receptor reduces cardiac transplant ischemia and reperfusion injury and mitigates CMV-accelerated chronic rejection.Am J Transplant2021
33228102Rat Cytomegalovirus Virion-Associated Proteins R131 and R129 Are Necessary for Infection of Macrophages and Dendritic Cells.Pathogens2020
31935257A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy.PLoS One2020
30917980Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs.Antimicrob Agents Chemother2019
31736977Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease.Front Immunol2019
31848362Characterization of a live-attenuated HCMV-based vaccine platform.Sci Rep2019
31431555Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34[+] Hematopoietic Progenitor Cells and Humanized NSG Mice.mBio2019
31316006Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity.Sci Transl Med2019
29343712Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology.Nat Commun2018
28628616Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.PLoS Negl Trop Dis2017
28278237Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.PLoS Pathog2017
28380070Correction: Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.PLoS Pathog2017
28428537Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice.Sci Rep2017
25766876Rat Cytomegalovirus Vaccine Prevents Accelerated Chronic Rejection in CMV-Naïve Recipients of Infected Donor Allograft Hearts.Am J Transplant2015
24161922HCMV infection of humanized mice after transplantation of G-CSF-mobilized peripheral blood stem cells from HCMV-seropositive donors.Biol Blood Marrow Transplant2014
24829346Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes.J Virol2014
24639226Fluorescence-based laser capture microscopy technology facilitates identification of critical in vivo cytomegalovirus transcriptional programs.Methods Mol Biol2014
24691437Cytomegalovirus pp65 limits dissemination but is dispensable for persistence.J Clin Invest2014
23936572Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity.PLoS Negl Trop Dis2013
22915808Cytomegalovirus CC chemokine promotes immune cell migration.J Virol2012
20980502Cytomegalovirus microRNA expression is tissue specific and is associated with persistence.J Virol2011
22241980A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection.PLoS Pathog2011
22052378Simian varicella virus gene expression during acute and latent infection of rhesus macaques.J Neurovirol2011
21199347Cytomegalovirus latency promotes cardiac lymphoid neogenesis and accelerated allograft rejection in CMV naïve recipients.Am J Transplant2011
20930069IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin.Blood2011
20833379Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model.Cell Host Microbe2010
19349057Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells.Virology2009
18093265The role of angiogenic and wound repair factors during CMV-accelerated transplant vascular sclerosis in rat cardiac transplants.Am J Transplant2008
18448536Human cytomegalovirus secretome contains factors that induce angiogenesis and wound healing.J Virol2008
17251289Rat cytomegalovirus gene expression in cardiac allograft recipients is tissue specific and does not parallel the profiles detected in vitro.J Virol2007
17175227Cytomegalovirus accelerates chronic allograft nephropathy in a rat renal transplant model with associated provocative chemokine profiles.Transplant Proc2006
15707397Rat cytomegalovirus-accelerated transplant vascular sclerosis is reduced with mutation of the chemokine-receptor R33.Am J Transplant2005
16051870Mouse cytomegalovirus M33 is necessary and sufficient in virus-induced vascular smooth muscle cell migration.J Virol2005
12525653Cytomegalovirus-mediated upregulation of chemokine expression correlates with the acceleration of chronic rejection in rat heart transplants.J Virol2003
11907411Elimination of donor-specific alloreactivity prevents cytomegalovirus-accelerated chronic rejection in rat small bowel and heart transplants.Transplantation2002
11267529Kinetics and development of CMV-accelerated transplant vascular sclerosis in rat cardiac allografts is linked to early increase in chemokine expression and presence of virus.Transplant Proc2001
8508678Linkage mapping detects two secondary microdeletions in cell hybrid HHW1064, used to isolate DNA probes from within 5q11.2-->q13.3.Cytogenet Cell Genet1993
1674144A polymorphic DNA marker at the D8S131 locus.Nucleic Acids Res1991
1762937Dinucleotide repeat polymorphism at the D5S260 locus on chromosome 5q.Nucleic Acids Res1991
1945862Dinucleotide repeat polymorphisms at the D5S257 and D5S268 loci on chromosome 5p.Nucleic Acids Res1991
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Collaborators

Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 45
Oregon Health and Science University
Co-authored papers 18
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Co-authored papers 14
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 13
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Co-authored papers 6
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Co-authored papers 6
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Co-authored papers 5
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 5
University of Colorado Anschutz Medical Campus
Co-authored papers 5
University of North Carolina at Chapel Hill.
Co-authored papers 4
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 4
Washington University School of Medicine
Co-authored papers 3
Oregon Health & Science University
Co-authored papers 3
Oregon Health & Science University
Co-authored papers 3
Pacific Northwest National Laboratory
Co-authored papers 2
Vanderbilt University Medical Center
Co-authored papers 2
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 2
The Roslin Institute, The University of Edinburgh
Co-authored papers 2
Louisiana State University
Co-authored papers 2
Oregon Health & Science University
Co-authored papers 2
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 2
Co-authored papers 2
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Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 1
J. Craig Venter Institute
Co-authored papers 1
Pacific Northwest National Laboratory
Co-authored papers 1
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1