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Author Details

Brian D Juran
Mayo Clinic
1998
60
29
PMIDPaper TitleJournal TitlePublished Year
36639314Corrigendum to: "An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs" [J Hepatol 75 (2021) 572-581].J Hepatol2023
37076803Predicting cholangiocarcinoma in primary sclerosing cholangitis: using artificial intelligence, clinical and laboratory data.BMC Gastroenterol2023
36687160Environmental chemicals and endogenous metabolites in bile of USA and Norway patients with primary sclerosing cholangitis.Exposome2023
34519176Induced Pluripotent Stem Cells From Subjects With Primary Sclerosing Cholangitis Develop a Senescence Phenotype Following Biliary Differentiation.Hepatol Commun2022
35473391DNA methylation profile of liver tissue in end-stage cholestatic liver disease.Epigenomics2022
34825528High-Resolution Exposomics and Metabolomics Reveals Specific Associations in Cholestatic Liver Diseases.Hepatol Commun2022
33226645Bile Acid Profiles in Primary Sclerosing Cholangitis and Their Ability to Predict Hepatic Decompensation.Hepatology2021
33794792Evaluation of circulating cell-free DNA in cholestatic liver disease using liver-specific methylation markers.BMC Gastroenterol2021
34552080A scalable workflow to characterize the human exposome.Nat Commun2021
34563121The PSC scientific community resource: an asset for multi-omics interrogation of primary sclerosing cholangitis.BMC Gastroenterol2021
29742811Primary Sclerosing Cholangitis Risk Estimate Tool (PREsTo) Predicts Outcomes of the Disease: A Derivation and Validation Study Using Machine Learning.Hepatology2020
31701542Studying the Exposome to Understand the Environmental Determinants of Complex Liver Diseases.Hepatology2020
32914644Genome-wide resolution peripheral blood methylome profiling reveals signatures for cholestatic liver disease.Epigenomics2020
32724082Single-cell mass cytometry on peripheral blood identifies immune cell subsets associated with primary biliary cholangitis.Sci Rep2020
28779025Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.Gut2018
29881819External validation of the United Kingdom-primary biliary cholangitis risk scores of patients with primary biliary cholangitis treated with ursodeoxycholic acid.Hepatol Commun2018
27992413Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.Nat Genet2017
28461130Doublecortin domain containing protein 2 (DCDC2) genetic variants in primary sclerosing cholangitis.J Hepatol2017
28274849Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis.Gastroenterology2017
28245345Variations in primary sclerosing cholangitis across the age spectrum.J Gastroenterol Hepatol2017
28695657HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry.HLA2017
26974007Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.Nat Genet2016
27062298Low incidence of primary biliary cirrhosis (PBC) in the first-degree relatives of PBC probands after 8 years of follow-up.Liver Int2016
27002801Duration of Inflammatory Bowel Disease Is Associated With Increased Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis and IBD.Am J Gastroenterol2016
25783671A comprehensive assessment of environmental exposures among 1000 North American patients with primary sclerosing cholangitis, with and without inflammatory bowel disease.Aliment Pharmacol Ther2015
26276523Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma.Cancer Med2015
26676814Genome-Wide Association Studies in Primary Biliary Cirrhosis.Semin Liver Dis2015
26394269International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.Nat Commun2015
25655558Association Between HLA Haplotypes and Increased Serum Levels of IgG4 in Patients With Primary Sclerosing Cholangitis.Gastroenterology2015
24440215Reduced coffee consumption among individuals with primary sclerosing cholangitis but not primary biliary cirrhosis.Clin Gastroenterol Hepatol2014
25057950Environmental factors in primary biliary cirrhosis.Semin Liver Dis2014
24517468Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease.Liver Int2014
24317935Biochemical response to ursodeoxycholic acid predicts survival in a North American cohort of primary biliary cirrhosis patients.J Gastroenterol2014
23490343Questionnaire based assessment of risk factors for primary biliary cirrhosis.Dig Liver Dis2013
23603763Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.Nat Genet2013
22257840Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes.Genes Immun2012
22936693Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants.Hum Mol Genet2012
22521342Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci.J Hepatol2012
21151127Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.Nat Genet2011
21538286Genomics in the post-GWAS era.Semin Liver Dis2011
21134112Genetic polymorphisms of matrix metalloproteinase 3 in primary sclerosing cholangitis.Liver Int2011
20638243Update on the genetics and genomics of PBC.J Autoimmun2010
20955967Primary biliary cirrhosis.Best Pract Res Clin Gastroenterol2010
20639879Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis.Nat Genet2010
20578265Carriage of a tumor necrosis factor polymorphism amplifies the cytotoxic T-lymphocyte antigen 4 attributed risk of primary biliary cirrhosis: evidence for a gene-gene interaction.Hepatology2010
19458352Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.N Engl J Med2009
19491853Common genetic variation and haplotypes of the anion exchanger SLC4A2 in primary biliary cirrhosis.Am J Gastroenterol2009
18041714Interacting alleles of the coinhibitory immunoreceptor genes cytotoxic T-lymphocyte antigen 4 and programmed cell-death 1 influence risk and features of primary biliary cirrhosis.Hepatology2008
18778710Primary biliary cirrhosis is associated with a genetic variant in the 3' flanking region of the CTLA4 gene.Gastroenterology2008
18456185Genetics and genomics of primary biliary cirrhosis.Clin Liver Dis2008
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Collaborators

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University of Toronto
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Baylor College of Medicine
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Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Wellcome Sanger Institute
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Chaohu Hospital Affiliated to Anhui Medical University
Co-authored papers 4
Institute for Clinical and Translational Research, Baylor College of Medicine
Co-authored papers 3
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University of California davis
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University of Cambridge
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Oslo University Hospital & Institute of Clinical Medicine, University of Oslo
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