Author details

Full Name

Liang Xu

Affiliation

ORCID

Career Start Year

2013

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37395400	Establishing artificial gene connections through RNA displacement-assembly-controlled CRISPR/Cas9 function.		2023
34788038	Building Endogenous Gene Connections through RNA Self-Assembly Controlled CRISPR/Cas9 Function.	Journal of the American Chemical Society	2021
33949481	Theophylline-induced synergic activation of guide RNA to control CRISPR/Cas9 function.	Chemical Communications	2021
34257868	Controllable DNA strand displacement by independent metal-ligand complexation.	Chemical Science	2021
34140682	Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II.	Nat Chem Biol	2021
34341342	A kinetically controlled platform for ligand-oligonucleotide transduction.	Nature Communications	2021
33068434	Conditional guide RNA through two intermediate hairpins for programmable CRISPR/Cas9 function: building regulatory connections between endogenous RNA expressions.	Nucleic Acids Research	2020
34094391	Photocontrol of CRISPR/Cas9 function by site-specific chemical modification of guide RNA.	Chemical Science	2020
32989164	Cockayne syndrome B protein acts as an ATP-dependent processivity factor that helps RNA polymerase II overcome nucleosome barriers.	Proc Natl Acad Sci U S A	2020
31179024	Intrinsic Cleavage of RNA Polymerase II Adopts a Nucleobase-independent Mechanism Assisted by Transcript Phosphate.	Nat Energy	2019
28239446	Mechanism of transcription-coupled DNA modification recognition.	Cell and Bioscience	2017
32288337	Transshipment hub selection from a shipper's and freight forwarder's perspective.	Expert Systems with Applications	2017
28933854	Epigenetic DNA Modification N<sup>6</sup>-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing.	J Am Chem Soc	2017
28784758	Mechanism of DNA alkylation-induced transcriptional stalling, lesion bypass, and mutagenesis.	Proc Natl Acad Sci U S A	2017
27791148	RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif.	Proc Natl Acad Sci U S A	2016
27436720	Benefits to energy efficiency and environmental impact: general discussion.	Faraday Discussions	2016
27435034	Developments for nuclear reactors and spent fuels processing: general discussion.	Faraday Discussions	2016
27105138	RNA polymerase II acts as a selective sensor for DNA lesions and endogenous DNA modifications.	Transcription	2016
27060150	Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution.	Nucleic Acids Res	2016
27091704	Bridge helix bending promotes RNA polymerase II backtracking through a critical and conserved threonine residue.	Nat Commun	2016
26123024	Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.	Nature	2015
25662224	Impact of template backbone heterogeneity on RNA polymerase II transcription.	Nucleic Acids Res	2015
26392149	RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.	Crit Rev Biochem Mol Biol	2015
24692664	Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues.	Nucleic Acids Research	2014
24883182	A Chemical Probe Targets DNA 5-Formylcytosine Sites and Inhibits TDG Excision, Polymerases Bypass, and Gene Expression.	Chemical Science	2014
25074911	Strand-specific (asymmetric) contribution of phosphodiester linkages on RNA polymerase II transcriptional efficiency and fidelity.	Proceedings of the National Academy of Sciences of the United States of America	2014
25159856	Pyrene-based quantitative detection of the 5-formylcytosine loci symmetry in the CpG duplex content during TET-dependent demethylation.	Angewandte Chemie - International Edition	2014
24767259	Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.	DNA Repair (Amst)	2014
24167045	A chemical perspective on transcriptional fidelity: dominant contributions of sugar integrity revealed by unlocked nucleic acids.	Angew Chem Int Ed Engl	2013