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Author Details

Michele K Anderson
Sunnybrook Research Institute, University of Toronto
1994
53
27
PMIDPaper TitleJournal TitlePublished Year
34870824Fetal Thymic Organ Culture (FTOC) Optimized for Gamma-Delta T Cell Studies.Methods Mol Biol2022
35705252Realization of the T Lineage Program Involves GATA-3 Induction of Bcl11b and Repression of Cdkn2b Expression.J Immunol2022
35848146Direct regulation of TCR rearrangement and expression by E proteins during early T cell development.WIREs Mech Dis2022
36405705Editorial: Molecular switches of the immune system: The E-protein/Id axis in hematopoietic development and function.Front Immunol2022
35990644Regulation of the Signal-Dependent E Protein HEBAlt Through a YYY Motif Is Required for Progression Through T Cell Development.Front Immunol2022
35983064Shifting gears: Id3 enables recruitment of E proteins to new targets during T cell development and differentiation.Front Immunol2022
33941655Cutting Edge: TCR-β Selection Is Required at the CD4<sup>+</sup>CD8<sup>+</sup> Stage of Human T Cell Development.J Immunol2021
34408144DL4-μbeads induce T cell lineage differentiation from stem cells in a stromal cell-free system.Nat Commun2021
34663592More Than Two to Tango: Mesenchymal Cells Are Required for Early T Cell Development.J Immunol2021
34107257Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo.Cell Rep2021
33058287Interaction between γδTCR signaling and the E protein-Id axis in γδ T cell development.Immunol Rev2020
33144398E2A regulates neural ectoderm fate specification in human embryonic stem cells.Development2020
31813827Precision Health Resource of Control iPSC Lines for Versatile Multilineage Differentiation.Stem Cell Reports2019
29754419Integration of T-cell receptor, Notch and cytokine signals programs mouse γδ T-cell effector differentiation.Immunol Cell Biol2018
28890536A key role for IL-7R in the generation of microenvironments required for thymic dendritic cells.Immunol Cell Biol2017
29222418HEB is required for the specification of fetal IL-17-producing γδ T cells.Nat Commun2017
28803914Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis.Stem Cell Reports2017
27265865A conserved alternative form of the purple sea urchin HEB/E2-2/E2A transcription factor mediates a switch in E-protein regulatory state in differentiating immune cells.Dev Biol2016
25866401Gamma delta T-cell differentiation and effector function programming, TCR signal strength, when and how much?Cell Immunol2015
24586038Editorial: GCN5 opens the door for the IRF-4-mediated cascade of B cell differentiation.J Leukoc Biol2014
23416670Changing course by lymphocyte lineage redirection.Nat Immunol2013
23476654Dendritic cell development: a choose-your-own-adventure story.Adv Hematol2013
22186727Transcriptional priming of intrathymic precursors for dendritic cell development.Development2012
22577461HEB in the spotlight: Transcriptional regulation of T-cell specification, commitment, and developmental plasticity.Clin Dev Immunol2012
21189289HEB-deficient T-cell precursors lose T-cell potential and adopt an alternative pathway of differentiation.Mol Cell Biol2011
20826759Context-dependent regulation of hematopoietic lineage choice by HEBAlt.J Immunol2010
21115673HEBAlt enhances the T-cell potential of fetal myeloid-biased precursors.Int Immunol2010
21061441Developmental progression of fetal HEB(-/-) precursors to the pre-T-cell stage is restored by HEBAlt.Eur J Immunol2010
19013443Transcription factor expression dynamics of early T-lymphocyte specification and commitment.Dev Biol2009
19668259Universal rules of immunity.Immunol Cell Biol2009
16448544At the crossroads: diverse roles of early thymocyte transcriptional regulators.Immunol Rev2006
17095691The genome of the sea urchin Strongylocentrotus purpuratus.Science2006
17027739The immune gene repertoire encoded in the purple sea urchin genome.Dev Biol2006
16785505The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors.J Immunol2006
15882585Subversion of T lineage commitment by PU.1 in a clonal cell line system.Dev Biol2005
15128764Evolutionary origins of lymphocytes: ensembles of T cell and B cell transcriptional regulators in a cartilaginous fish.J Immunol2004
15034051Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes.J Immunol2004
12871641GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation.Immunity2003
11869688Constitutive expression of PU.1 in fetal hematopoietic progenitors blocks T cell development at the pro-T cell stage.Immunity2002
12027437Definition of regulatory network elements for T cell development by perturbation analysis with PU.1 and GATA-3.Dev Biol2002
12027432Elements of transcription factor network design for T-lineage specification.Dev Biol2002
11149949Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria.Proc Natl Acad Sci U S A2001
11282996Complex expression patterns of lymphocyte-specific genes during the development of cartilaginous fish implicate unique lymphoid tissues in generating an immune repertoire.Int Immunol2001
10793477Transcription factor expression in lymphocyte development: clues to the evolutionary origins of lymphoid cell lineages?Curr Top Microbiol Immunol2000
9811969A long form of the skate IgX gene exhibits a striking resemblance to the new shark IgW and IgNARC genes.Immunogenetics1999
10462413Transcriptional regulation of lymphocyte lineage commitment.Bioessays1999
10358755Evolution of antigen binding receptors.Annu Rev Immunol1999
10423342Persistent effects of doxorubicin on cardiac gene expression.J Mol Cell Cardiol1999
10375504Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage.Development1999
9052832alpha, beta, gamma, and delta T cell antigen receptor genes arose early in vertebrate phylogeny.Immunity1997
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Collaborators

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Princess Margaret Cancer Centre
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Fox Chase Cancer Center
Co-authored papers 4
Auburn University
Co-authored papers 3
Montreal Neurological Institute, McGill University, 1 University Street
Co-authored papers 3
Macquarie University
Co-authored papers 2
California State University
Co-authored papers 2
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Co-authored papers 2
California Institute of Technology
Co-authored papers 2
George Washington University
Co-authored papers 2
George Washington University
Co-authored papers 2
Saitama University
Co-authored papers 2
Oakland University
Co-authored papers 2
Centers for Disease Control and Prevention
Co-authored papers 2
George Washington University
Co-authored papers 2
University of Maryland, College Park
Co-authored papers 2
Lund University, Linkoping University. .
Co-authored papers 2
University of Maryland Biotechnology Institute
Co-authored papers 2
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
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National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 1
Woods Hole Oceanographic Institution
Co-authored papers 1
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Instituto Cajal
Co-authored papers 1
The Affiliated Yantai Yuhuangding Hospital, Qingdao University
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