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Author Details

Jens Hansen
Icahn School of Medicine at Mount Sinai
2011
33
14
PMIDPaper TitleJournal TitlePublished Year
36824813Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury.bioRxiv2023
37528868Synaptojanin 1 Modulates Functional Recovery After Incomplete Spinal Cord Injury in Male Apolipoprotein E Epsilon 4 Mice.Neurotrauma Rep2023
37799971A spatially specified systems pharmacology therapy for axonal recovery after injury.Front Pharmacol2023
37616058Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients.J Clin Invest2023
37022786Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells.JCI Insight2023
37416508Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury.Front Cell Neurosci2023
36994727FN (Fibronectin)-Integrin α5 Signaling Promotes Thoracic Aortic Aneurysm in a Mouse Model of Marfan Syndrome.Arterioscler Thromb Vasc Biol2023
34669512Functional Effects of Cardiomyocyte Injury in COVID-19.J Virol2022
35675394A reference tissue atlas for the human kidney.Sci Adv2022
35567544Fibrillin-1 deficiency in the outer perichondrium causes longitudinal bone overgrowth in mice with Marfan syndrome.Hum Mol Genet2022
35926710Whole cell response to receptor stimulation involves many deep and distributed subcellular biochemical processes.J Biol Chem2022
35191471Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modelling a European cardiomyopathy with global impact.Cardiovasc Res2022
35058449Proteomic cellular signatures of kinase inhibitor-induced cardiotoxicity.Sci Data2022
34320838Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome.Arterioscler Thromb Vasc Biol2021
33679326The Human ApoE4 Variant Reduces Functional Recovery and Neuronal Sprouting After Incomplete Spinal Cord Injury in Male Mice.Front Cell Neurosci2021
34993473Extracellular histones, a new class of inhibitory molecules of CNS axonal regeneration.Brain Commun2021
34739849A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals.Stem Cell Reports2021
33941686Protein structure-based gene expression signatures.Proc Natl Acad Sci U S A2021
32968055Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity.Nat Commun2020
33200140Physiology of cardiomyocyte injury in COVID-19.medRxiv2020
32939051Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project.Nat Rev Nephrol2020
31167969Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms.JCI Insight2019
31272389OSCI: standardized stem cell ontology representation and use cases for stem cell investigation.BMC Bioinformatics2019
31434897Wilm's tumor 1 promotes memory flexibility.Nat Commun2019
31042702Dynamic balance between vesicle transport and microtubule growth enables neurite outgrowth.PLoS Comput Biol2019
29371244Cell Type-Specific Contributions of the Angiotensin II Type 1a Receptor to Aorta Homeostasis and Aneurysmal Disease-Brief Report.Arterioscler Thromb Vasc Biol2018
29116112A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries.Sci Rep2017
28134617Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells.Elife2017
29255142A flexible ontology for inference of emergent whole cell function from relationships between subcellular processes.Sci Rep2017
25923014Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy.Nat Commun2015
24324277Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes.Stem Cells Transl Med2014
23212109Computation as the mechanistic bridge between precision medicine and systems therapeutics.Clin Pharmacol Ther2013
22417173Systems pharmacology of complex diseases.Ann N Y Acad Sci2011
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Collaborators

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