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Author Details

Iain A McNeish
Ovarian Cancer Action Research Centre, Imperial College London
1996
182
52
PMIDPaper TitleJournal TitlePublished Year
36201707Reply to C. Marchetti et al.J Clin Oncol2023
37858464Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma.Cell Rep2023
37752102Author Correction: The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma.Nat Commun2023
37795443The potential and challenges of targeting <i>MTAP</i>-negative cancers beyond synthetic lethality.Front Oncol2023
37845213Molecular landscape and functional characterization of centrosome amplification in ovarian cancer.Nat Commun2023
37577760PTEN deficiency exposes a requirement for an ARF GTPase module for integrin-dependent invasion in ovarian cancer.EMBO J2023
37542936Survival and modelled cancer antigen-125 ELIMination rate constant K score in ovarian cancer patients in first-line before poly(ADP-ribose) polymerase inhibitor era: A Gynaecologic Cancer Intergroup meta-analysis.Eur J Cancer2023
37676655Biomarker Analysis of Vistusertib Plus Paclitaxel Regimen-Reply.JAMA Oncol2023
37220750Spatial and temporal intra-tumoral heterogeneity in advanced HGSOC: Implications for surgical and clinical outcomes.Cell Rep Med2023
37075255Benefit From Fractionated Dose-Dense Chemotherapy in Patients With Poor Prognostic Ovarian Cancer: ICON-8 Trial.JCO Clin Cancer Inform2023
37072323Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study.Int J Gynecol Cancer2023
37474499The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma.Nat Commun2023
36801617Mathematical modeling of the early modeled CA-125 longitudinal kinetics (KELIM-PARP) as a pragmatic indicator of rucaparib efficacy in patients with recurrent ovarian carcinoma in ARIEL2 &amp; STUDY 10.EBioMedicine2023
36672287British Gynaecological Cancer Society Recommendations for Evidence Based, Population Data Derived Quality Performance Indicators for Ovarian Cancer.Cancers (Basel)2023
36928279Efficacy and Safety of Weekly Paclitaxel Plus Vistusertib vs Paclitaxel Alone in Patients With Platinum-Resistant Ovarian High-Grade Serous Carcinoma: The OCTOPUS Multicenter, Phase 2, Randomized Clinical Trial.JAMA Oncol2023
35131874Dual G9A/EZH2 Inhibition Stimulates Antitumor Immune Response in Ovarian High-Grade Serous Carcinoma.Mol Cancer Ther2022
35841803Response to the letter entitled "Glomerular filtration rate estimation for carboplatin dosing in patients with gynaecological cancers".ESMO Open2022
35398881The Genomic Landscape of Early-Stage Ovarian High-Grade Serous Carcinoma.Clin Cancer Res2022
35690073Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal cancer treatment (ICON8): overall survival results from an open-label, randomised, controlled, phase 3 trial.Lancet Oncol2022
35658487A Randomized, Phase III Trial to Evaluate Rucaparib Monotherapy as Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer (ATHENA-MONO/GOG-3020/ENGOT-ov45).J Clin Oncol2022
35681688Risk Factors for Ovarian Cancer: An Umbrella Review of the Literature.Cancers (Basel)2022
36265336HPV vaccination and HPV-related malignancies: impact, strategies and optimizations toward global immunization coverage.Cancer Treat Rev2022
36289203Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer.Nat Commun2022
35918200A novel cell line panel reveals non-genetic mediators of platinum resistance and phenotypic diversity in high grade serous ovarian cancer.Gynecol Oncol2022
33414107Ovarian sex cord-stromal tumors: an update on clinical features, molecular changes, and management.Int J Gynecol Cancer2021
33907915The Emerging Role of Interleukin 1β (IL-1β) in Cancer Cachexia.Inflammation2021
33570999FrenchFISH: Poisson Models for Quantifying DNA Copy Number From Fluorescence In Situ Hybridization of Tissue Sections.JCO Clin Cancer Inform2021
33752918Population exposure-efficacy and exposure-safety analyses for rucaparib in patients with recurrent ovarian carcinoma from Study 10 and ARIEL2.Gynecol Oncol2021
33551198Corrigendum to "Pathological chemotherapy response score is prognostic in tubo-ovarian high-grade serous carcinoma: A systematic review and meta-analysis of individual patient data" Gynecol. Oncol. 154 (2019) 441-448.Gynecol Oncol2021
34893524Safety and efficacy of the tumor-selective adenovirus enadenotucirev with or without paclitaxel in platinum-resistant ovarian cancer: a phase 1 clinical trial.J Immunother Cancer2021
34647981Preexisting TP53-Variant Clonal Hematopoiesis and Risk of Secondary Myeloid Neoplasms in Patients With High-grade Ovarian Cancer Treated With Rucaparib.JAMA Oncol2021
34602290Characterization of patients with long-term responses to rucaparib treatment in recurrent ovarian cancer.Gynecol Oncol2021
34452316Strategies to Optimise Oncolytic Viral Therapies: The Role of Natural Killer Cells.Viruses2021
34564042The role of the tumor primary chemosensitivity relative to the success of the medical-surgical management in patients with advanced ovarian carcinomas.Cancer Treat Rev2021
34478639Activating a collaborative innate-adaptive immune response to control metastasis.Cancer Cell2021
34593565ATHENA (GOG-3020/ENGOT-ov45): a randomized, phase III trial to evaluate rucaparib as monotherapy (ATHENA-MONO) and rucaparib in combination with nivolumab (ATHENA-COMBO) as maintenance treatment following frontline platinum-based chemotherapy in ovarian cancer.Int J Gynecol Cancer2021
33941851Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53.Oncogene2021
33941784Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2).Nat Commun2021
34016703Metronomic oral cyclophosphamide in relapsed ovarian cancer.Int J Gynecol Cancer2021
34316715Characterization of a <i>RAD51C</i>-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance.NAR Cancer2021
34289354Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING.Cell Rep2021
33032491Safe administration of chemotherapy in mast cell activation syndrome.J Oncol Pharm Pract2021
33357510Objective responses to first-line neoadjuvant carboplatin-paclitaxel regimens for ovarian, fallopian tube, or primary peritoneal carcinoma (ICON8): post-hoc exploratory analysis of a randomised, phase 3 trial.Lancet Oncol2021
32195317NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer.Mol Ther Oncolytics2020
31727629Prophylactic <i>In Vivo</i> Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models.Cancer Res2020
32098980Oncologist-led BRCA 'mainstreaming' in the ovarian cancer clinic: A study of 255 patients and its impact on their management.Sci Rep2020
31940491Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.Cell Rep2020
32919511Progression-free survival in the ICON8 trial - Authors' reply.Lancet2020
32932156Organoid models in gynaecological oncology research.Cancer Treat Rev2020
32615110Weekly platinum-based chemotherapy versus 3-weekly platinum-based chemotherapy for newly diagnosed ovarian cancer (ICON8): quality-of-life results of a phase 3, randomised, controlled trial.Lancet Oncol2020
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Collaborators

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Duke School of Medicine
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College of Nursing, University of South Florida
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Perlmutter Cancer Center
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David Geffen School of Medicine, University of California los angeles
Co-authored papers 25
Mayo Clinic College of Medicine
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Rollins School of Public Health, Emory University
Co-authored papers 24
University of Southern California
Co-authored papers 24
School of Clinical Medicine, University of NSW Sydney, Lowy Cancer Research Centre
Co-authored papers 24
International Hereditary Cancer Center, Pomeranian Medical University
Co-authored papers 24
University of Cambridge
Co-authored papers 24
Otto-Friedrich-University Bamberg
Co-authored papers 24
Fred Hutchinson Cancer Research Center
Co-authored papers 24
German Cancer Research Center (DKFZ)
Co-authored papers 24
National Cancer Institute, National Institutes of Health
Co-authored papers 23
Pomeranian Medical University
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Oregon Health & Science University
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University of Michigan School of Public Health ann arbor
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Cedars-Sinai Medical Center
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Ovarian Cancer Action Research Centre, Imperial College London
Co-authored papers 23
Huntsman Cancer Institute, University of Utah
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University of California irvine
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UCL EGA Institute for Women's Health, University College London
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