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Author Details

Gopinath M Subramanian
John Hunter Children's Hospital
2002
157
64
PMIDPaper TitleJournal TitlePublished Year
37075704Integration of deep learning-based histopathology and transcriptomics reveals key genes associated with fibrogenesis in patients with advanced NASH.Cell Rep Med2023
37087635Dominant-negative variants in CBX1 cause a neurodevelopmental disorder.Genet Med2023
37340737CSF neopterin and quinolinic acid are biomarkers of neuroinflammation and neurotoxicity in FIRES and other infection-triggered encephalopathy syndromes.Ann Clin Transl Neurol2023
36240780En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH.Cell2022
35835205Elevated de novo lipogenesis, slow liver triglyceride turnover, and clinical correlations in nonalcoholic steatohepatitis patients.J Lipid Res2022
35906407Dilatation of the bridging cerebral cortical veins in childhood hydrocephalus suggests a malfunction of venous impedance pumping.Sci Rep2022
32707342Inter- and Intra-individual Variation, and Limited Prognostic Utility, of Serum Alkaline Phosphatase in a Trial of Patients With Primary Sclerosing Cholangitis.Clin Gastroenterol Hepatol2021
33570776A Machine Learning Approach Enables Quantitative Measurement of Liver Histology and Disease Monitoring in NASH.Hepatology2021
33169409Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH.Hepatology2021
33029936Leukoencephalopathy with calcifications and cysts: Genetic and phenotypic spectrum.Am J Med Genet A2021
32915202DNA Methylation and Immune Cell Markers Demonstrate Evidence of Accelerated Aging in Patients with Chronic Hepatitis B Virus or Hepatitis C Virus, with or without Human Immunodeficienct Virus Co-infection.Clin Infect Dis2021
32559475Disease characteristics of MCT8 deficiency: an international, retrospective, multicentre cohort study.Lancet Diabetes Endocrinol2020
32087795Switching from tenofovir disoproxil fumarate to tenofovir alafenamide in virologically suppressed patients with chronic hepatitis B: a randomised, double-blind, phase 3, multicentre non-inferiority study.Lancet Gastroenterol Hepatol2020
31907854Spontaneous Fluctuations in Liver Biochemistries in Patients with Compensated NASH Cirrhosis: Implications for Drug Hepatotoxicity Monitoring.Drug Saf2020
33071176PNPLA3 polymorphisms are associated with raised alanine aminotransferase levels in hepatitis C virus genotype 3.Arab J Gastroenterol2020
32993698The incidence of obesity, venous sinus stenosis and cerebral hyperaemia in children referred for MRI to rule out idiopathic intracranial hypertension at a tertiary referral hospital: a 10 year review.Fluids Barriers CNS2020
33014081Sources and Toxicity of Mercury in the San Francisco Bay Area, Spanning California and Beyond.J Environ Public Health2020
32923831Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH.Hepatol Commun2020
32115759Cilofexor, a Nonsteroidal FXR Agonist, in Patients With Noncirrhotic NASH: A Phase 2 Randomized Controlled Trial.Hepatology2020
32523627Plasma eicosanoids as noninvasive biomarkers of liver fibrosis in patients with nonalcoholic steatohepatitis.Therap Adv Gastroenterol2020
32384174HBV variants are common in the 'immune-tolerant' phase of chronic hepatitis B.J Viral Hepat2020
32349763The incidence of significant venous sinus stenosis and cerebral hyperemia in childhood hydrocephalus: prognostic value with regards to differentiating active from compensated disease.Fluids Barriers CNS2020
30661255The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS-9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis.Hepatology2019
31909352Durability of Hepatitis B Surface Antigen Loss With Nucleotide Analogue and Peginterferon Therapy in Patients With Chronic Hepatitis B.Hepatol Commun2019
32039401Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis.JHEP Rep2019
30153359Simtuzumab for Primary Sclerosing Cholangitis: Phase 2 Study Results With Insights on the Natural History of the Disease.Hepatology2019
31271665Noninvasive Tests Accurately Identify Advanced Fibrosis due to NASH: Baseline Data From the STELLAR Trials.Hepatology2019
31356634Genomic modeling of hepatitis B virus integration frequency in the human genome.PLoS One2019
31324819Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients.Sci Rep2019
31379058Predicting HBsAg clearance in genotype A chronic hepatitis B using HBsAg epitope profiling: A biomarker for functional cure.Liver Int2019
31306680Anti-PD-1 blockade with nivolumab with and without therapeutic vaccination for virally suppressed chronic hepatitis B: A pilot study.J Hepatol2019
31478832Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes.Elife2019
31274575Expansion of phenotype of DDX3X syndrome: six new cases.Clin Dysmorphol2019
30790229Sofosbuvir-velpatasvir single-tablet regimen administered for 12 weeks in a phase 3 study with minimal monitoring in India.Hepatol Int2019
30993748The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials.Hepatology2019
30930022Combined GS-4774 and Tenofovir Therapy Can Improve HBV-Specific T-Cell Responses in Patients With Chronic Hepatitis.Gastroenterology2019
30324553Correction to: Hepatitis B Surface Antigen Loss with Tenofovir Disoproxil Fumarate Plus Peginterferon Alfa-2a: Week 120 Analysis.Dig Dis Sci2019
30590481Discovery of Half-life of Circulating Hepatitis B Surface Antigen in Patients With Chronic Hepatitis B Infection Using Heavy Water Labeling.Clin Infect Dis2019
28892558The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial.Hepatology2018
30136045Hepatitis B Surface Antigen Loss with Tenofovir Disoproxil Fumarate Plus Peginterferon Alfa-2a: Week 120 Analysis.Dig Dis Sci2018
29859740Deferred treatment with sofosbuvir-velpatasvir-voxilaprevir for patients with chronic hepatitis C virus who were previously treated with an NS5A inhibitor: an open-label substudy of POLARIS-1.Lancet Gastroenterol Hepatol2018
29990488Simtuzumab Is Ineffective for Patients With Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis.Gastroenterology2018
29933096Improved Bone Safety of Tenofovir Alafenamide Compared to Tenofovir Disoproxil Fumarate Over 2 Years in Patients With Chronic HBV Infection.Clin Gastroenterol Hepatol2018
29958855Efficacy of Sofosbuvir and Velpatasvir, With and Without Ribavirin, in Patients With Hepatitis C Virus Genotype 3 Infection and Cirrhosis.Gastroenterology2018
30144554The conundrum of cryptogenic cirrhosis: Adverse outcomes without treatment options.J Hepatol2018
29982508Identification of a Novel Hepatitis C Virus Genotype From Punjab, India: Expanding Classification of Hepatitis C Virus Into 8 Genotypes.J Infect Dis2018
29851204Safety and efficacy of vesatolimod (GS-9620) in patients with chronic hepatitis B who are not currently on antiviral treatment.J Viral Hepat2018
30059671GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease.Gastroenterology2018
30413629Neurologic phenotypes associated with <i>COL4A1</i>/<i>2</i> mutations: Expanding the spectrum of disease.Neurology2018
29378197TLR7 Agonist Increases Responses of Hepatitis B Virus-Specific T Cells and Natural Killer Cells in Patients With Chronic Hepatitis B Treated With Nucleos(T)Ide Analogues.Gastroenterology2018
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Collaborators

Johns Hopkins University School of Medicine
Co-authored papers 15
Center for Liver Diseases, Inova Fairfax Hospital
Co-authored papers 14
Co-authored papers 9
Co-authored papers 9
Pinnacle Clinical Research Center
Co-authored papers 8
Inc.Foster CityCA.
Co-authored papers 5
Co-authored papers 5
University Clinic for Visceral Surgery and Medicine, Bern University
Co-authored papers 4
Inc., 9800 Medical Center Drive
Co-authored papers 4
Kyungpook National University
Co-authored papers 4
Co-authored papers 4
Virginia Commonwealth University
Co-authored papers 4
National Cancer Institute, National Institutes of Health
Co-authored papers 4
University of Utah
Co-authored papers 3
Center for Computational Biology, Johns Hopkins University
Co-authored papers 3
Beth Israel Deaconess Medical Center, Harvard Medical School
Co-authored papers 3
Co-authored papers 3
The J. Craig Venter Institute
Co-authored papers 3
Duke Clinical Research Institute and Duke University School of Medicine
Co-authored papers 3
Beth Israel Deaconess Medical Center, Harvard Medical School
Co-authored papers 3
University of California berkeley
Co-authored papers 3
University of New Mexico Health Sciences Center
Co-authored papers 2
Charles University and Motol University Hospital
Co-authored papers 2
Department of Pharmacy, Liyang People's Hospital
Co-authored papers 2
University of Wurzburg
Co-authored papers 2
National Institute of Diabetes and Digestive and Kidney Diseases
Co-authored papers 2
Co-authored papers 2
University of Geneva
Co-authored papers 2
Co-authored papers 2
Oncology R&D
Co-authored papers 2