Author details

Full Name

Zandrea Ambrose

Affiliation

ORCID

Career Start Year

2001

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38060615	Deep analysis of CD4 T cells in the rhesus CNS during SIV infection.	PLoS Pathog	2023
37662237	CD4 T cell Responses in the CNS during SIV infection.	bioRxiv	2023
37816950	Use of pediatric thymus to humanize mice for HIV-1 mucosal transmission.		2023
35137972	Construction and characterization of two SARS-CoV-2 minigenome replicon systems.	Journal of Medical Virology	2022
35957953	APOBEC3 selects V179I in HIV-1 reverse transcriptase to provide selective advantage for non-nucleoside reverse transcriptase inhibitor-resistant mutants.		2022
36597530	Targeting Spike Glycans to Inhibit SARS-CoV2 Viral Entry.	bioRxiv	2022
34835043	Disassembling the Nature of Capsid: Biochemical, Genetic, and Imaging Approaches to Assess HIV-1 Capsid Functions.	Viruses	2021
34232063	CG Dinucleotide Removal in Bioluminescent and Fluorescent Reporters Improves HIV-1 Replication and Reporter Gene Expression for Dual Imaging in Humanized Mice.	Journal of Virology	2021
33758083	Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner.	mBio	2021
35062252	SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV- Co-Infection.	Viruses	2021
33332391	Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis.	PLoS Biology	2020
31969438	Long-Acting Rilpivirine (RPV) Preexposure Prophylaxis Does Not Inhibit Vaginal Transmission of RPV-Resistant HIV-1 or Select for High-Frequency Drug Resistance in Humanized Mice.	Journal of Virology	2020
32730321	SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis.	PLoS Pathogens	2020
30894467	Two Coselected Distal Mutations in HIV-1 Reverse Transcriptase (RT) Alter Susceptibility to Nonnucleoside RT Inhibitors and Nucleoside Analogs.	Journal of Virology	2019
31844138	AutoCLEM: An Automated Workflow for Correlative Live-Cell Fluorescence Microscopy and Cryo-Electron Tomography.	Scientific Reports	2019
30814280	CA Mutation N57A Has Distinct Strain-Specific HIV-1 Capsid Uncoating and Infectivity Phenotypes.	J Virol	2019
31167922	A Novel Phenotype Links HIV-1 Capsid Stability to cGAS-Mediated DNA Sensing.	Journal of Virology	2019
29643241	Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid.	J Virol	2018
28794041	Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon.	J Virol	2017
28542550	A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.	PLoS Pathog	2017
27124362	Rilpivirine and Doravirine Have Complementary Efficacies Against NNRTI-Resistant HIV-1 Mutants.	Journal of acquired immune deficiency syndromes (1999)	2016
26880034	Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants.	Retrovirology	2016
27356901	Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.	J Virol	2016
26297664	Visualization and quantification of simian immunodeficiency virus-infected cells using non-invasive molecular imaging.	Journal of General Virology	2015
26438501	Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase.	Antimicrobial Agents and Chemotherapy	2015
26559632	Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy.	Retrovirology	2015
24559861	HIV-1 uncoating: connection to nuclear entry and regulation by host proteins.	Virology	2014
24784552	Dysregulation of multiple inflammatory molecules in lymph node and ileum of macaques during RT-SHIV infection with or without antiretroviral therapy.	Journal of Medical Primatology	2014
24367650	Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model.	PLoS One	2013
23835323	Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay.	Retrovirology	2013
22316150	Identification of HIV inhibitors guided by free energy perturbation calculations.	Current Pharmaceutical Design	2012
22933296	Ultrasensitive allele-specific PCR reveals rare preexisting drug-resistant variants and a large replicating virus population in macaques infected with a simian immunodeficiency virus containing human immunodeficiency virus reverse transcriptase.	J Virol	2012
22301145	Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection.	Journal of Virology	2012
22078557	Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography.	Structure	2011
21084490	Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy.	J Virol	2011
20227665	Flexible use of nuclear import pathways by HIV-1.		2010
19889213	RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy.	Retrovirology	2009
19255423	A macaque model of HIV-1 infection.	Proc Natl Acad Sci U S A	2009
19678643	The nucleoside analogue D-carba T blocks HIV-1 reverse transcription.	Journal of Medicinal Chemistry	2009
19193782	The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs.	Journal of Virology	2009
18434406	Incomplete protection against simian immunodeficiency virus vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges.	J Virol	2008
17286555	Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.	Biochemical Journal	2007
17597154	The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants.	Journal of Molecular Biology	2007
17574286	HIV/AIDS: in search of an animal model.	Trends Biotechnol	2007
17855539	Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy.	J Virol	2007
16474164	The level of reverse transcriptase (RT) in human immunodeficiency virus type 1 particles affects susceptibility to nonnucleoside RT inhibitors but not to lamivudine.	Journal of Virology	2006
15564466	In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques.	Journal of Virology	2004
12706101	Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6).	Virology	2003
11507204	Evidence for early local viral replication and local production of antiviral immunity upon mucosal simian-human immunodeficiency virus SHIV(89.6) infection in Macaca nemestrina.	Journal of Virology	2001