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Author Details
Full Name
Michael H B Stowell
Affiliation
University of Colorado Boulder
ORCID
Career Start Year
1993
Papers
50
H Index
23
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36959978
A simple flash and freeze system for cryogenic time-resolved electron microscopy.
Front Mol Biosci
2023
35301478
Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat Struct Mol Biol
2022
35819763
Electron Tomographic Methods for Studying Organelles of the Murine Chemical Synapse.
Methods Mol Biol
2022
35361965
Synergistic activation of the insulin receptor via two distinct sites.
Nat Struct Mol Biol
2022
35753663
Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines.
Mol Cell Proteomics
2022
36369335
Progress and gaps of extracellular vesicle-mediated intercellular cargo transfer in the central nervous system.
Commun Biol
2022
36151101
Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun
2022
35247328
Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell
2022
33440145
SNARE Zippering Is Suppressed by a Conformational Constraint that Is Removed by v-SNARE Splitting.
Cell Rep
2021
34616284
Room for Two: The Synaptophysin/Synaptobrevin Complex.
Front Synaptic Neurosci
2021
34099171
Purification of a native nicotinic receptor.
Methods Enzymol
2021
33326751
Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals.
Cell Syst
2021
32275860
Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins.
Neuron
2020
32060372
An isothermal shift assay for proteome scale drug-target identification.
Commun Biol
2020
32893496
On-Chip Acousto Thermal Shift Assay for Rapid and Sensitive Assessment of Protein Thermodynamic Stability.
Small
2020
30642129
Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-Based Antioxidant Strategies.
Int J Mol Sci
2019
31875562
Intracellular Vesicle Fusion Requires a Membrane-Destabilizing Peptide Located at the Juxtamembrane Region of the v-SNARE.
Cell Rep
2019
31801276
Flattening of Diluted Species Profile via Passive Geometry in a Microfluidic Device.
Micromachines (Basel)
2019
31387992
Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways.
Nat Commun
2019
31227607
Cryo-EM structure of OSCA1.2 from <i>Oryza sativa</i> elucidates the mechanical basis of potential membrane hyperosmolality gating.
Proc Natl Acad Sci U S A
2019
30317509
Functional Reconstitution of Intracellular Vesicle Fusion Using Purified SNAREs and Sec1/Munc18 (SM) Proteins.
Methods Mol Biol
2019
30275014
The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis.
J Biol Chem
2018
30127032
SNARE zippering requires activation by SNARE-like peptides in Sec1/Munc18 proteins.
Proc Natl Acad Sci U S A
2018
28792968
Identification of the primary peptide contaminant that inhibits fibrillation and toxicity in synthetic amyloid-β42.
PLoS One
2017
26874206
Exosomes and other extracellular vesicles in neural cells and neurodegenerative diseases.
Biochim Biophys Acta
2016
26431309
Reconstituting Intracellular Vesicle Fusion Reactions: The Essential Role of Macromolecular Crowding.
J Am Chem Soc
2015
26333660
Architecture of the Synaptophysin/Synaptobrevin Complex: Structural Evidence for an Entropic Clustering Function at the Synapse.
Sci Rep
2015
24379376
Self-assembled lipid and membrane protein polyhedral nanoparticles.
Proc Natl Acad Sci U S A
2014
23381628
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome.
Nat Struct Mol Biol
2013
20138128
Loss of synaptotagmin IV results in a reduction in synaptic vesicles and a distortion of the Golgi structure in cultured hippocampal neurons.
Neuroscience
2010
20637753
In vivo adsorption of autoantibodies in myasthenia gravis using Nanodisc-incorporated acetylcholine receptor.
Exp Neurol
2010
17327160
Electron tomographic methods for studying the chemical synapse.
Methods Cell Biol
2007
17562317
Structure of synaptophysin: a hexameric MARVEL-domain channel protein.
Structure
2007
16552147
Rapid and simple protein-stability screens: application to membrane proteins.
Acta Crystallogr D Biol Crystallogr
2006
15339954
Phylogenetic conservation of disulfide-linked, dimeric acetylcholine receptor pentamers in southern ocean electric rays.
J Exp Biol
2004
11242086
GTPase activity of dynamin and resulting conformation change are essential for endocytosis.
Nature
2001
10559860
Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring.
Nat Cell Biol
1999
10329178
Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall.
J Mol Biol
1999
9818263
Macromolecular structure determination by electron microscopy: new advances and recent results.
Curr Opin Struct Biol
1998
9631291
The functional significance of multimerization in ion channels.
Curr Opin Struct Biol
1998
9063865
Redox-dependent structural changes in the nitrogenase P-cluster.
Biochemistry
1997
9115209
Light-induced structural changes in photosynthetic reaction center: implications for mechanism of electron-proton transfer.
Science
1997
9235936
Electron paramagnetic resonance studies of succinate:ubiquinone oxidoreductase from Paracoccus denitrificans. Evidence for a magnetic interaction between the 3Fe-4S cluster and cytochrome b.
J Biol Chem
1997
9020789
Uncompetitive substrate inhibition and noncompetitive inhibition by 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole (UHDBT) and 2-n-nonyl-4-hydroxyquinoline-N-oxide (NQNO) is observed for the cytochrome bo3 complex: implications for a Q(H2)-loop proton translocation mechanism.
Biochemistry
1997
8946850
A leucine-rich repeat variant with a novel repetitive protein structural motif.
Nat Struct Biol
1996
7771322
Structure and stability of membrane proteins.
Adv Protein Chem
1995
8644492
Cytochrome c oxidase: chemistry of a molecular machine.
Adv Enzymol Relat Areas Mol Biol
1995
8378035
Shedding light on the use of heat to treat HIV infections.
Oncology
1993
8253216
Further comparison of ubiquinol and cytochrome c terminal oxidases.
FEBS Lett
1993
8392948
Comparison of ubiquinol and cytochrome c terminal oxidases. An alternative view.
FEBS Lett
1993
1 - 50 of 50
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Howard Hughes Medical Institute, California Institute of Technology
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Skidmore College
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Skaggs School of Pharmacy and Pharmaceutical Sciences.
Co-authored papers
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University of Colorado Anschutz Medical Campus
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Michael C Wiener
University of Virginia
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1
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University of California San Francisco
Co-authored papers
1
Andrew P Yeh
Accelero Biostructures Inc.
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1
Ian G Mills
Queen's University Belfast
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1
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University of California at San Diego
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Jacobs School of Medicine and Biomedical Sciences, University of Buffalo
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1
Burkhard Rost
Technical University of Munich (TUM)
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1
Raymond C Stevens
iHuman Institute, ShanghaiTech University
Co-authored papers
1
Christopher C Ebmeier
University of Colorado
Co-authored papers
1
Wayne A Hendrickson
Columbia University
Co-authored papers
1
James J Chou
Harvard Medical School
Co-authored papers
1
Rosa Rademakers
University of Antwerp
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1
Julie A Reisz
University of Colorado Anschutz Medical Campus
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1
Avner Schlessinger
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Mark E Dumont
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1
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