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Author Details

Michael H B Stowell
University of Colorado Boulder
1993
50
23
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36959978A simple flash and freeze system for cryogenic time-resolved electron microscopy.Front Mol Biosci2023
35301478Structural mechanism of muscle nicotinic receptor desensitization and block by curare.Nat Struct Mol Biol2022
35819763Electron Tomographic Methods for Studying Organelles of the Murine Chemical Synapse.Methods Mol Biol2022
35361965Synergistic activation of the insulin receptor via two distinct sites.Nat Struct Mol Biol2022
35753663Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines.Mol Cell Proteomics2022
36369335Progress and gaps of extracellular vesicle-mediated intercellular cargo transfer in the central nervous system.Commun Biol2022
36151101Activation of the insulin receptor by an insulin mimetic peptide.Nat Commun2022
35247328Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.Cell2022
33440145SNARE Zippering Is Suppressed by a Conformational Constraint that Is Removed by v-SNARE Splitting.Cell Rep2021
34616284Room for Two: The Synaptophysin/Synaptobrevin Complex.Front Synaptic Neurosci2021
34099171Purification of a native nicotinic receptor.Methods Enzymol2021
33326751Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals.Cell Syst2021
32275860Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins.Neuron2020
32060372An isothermal shift assay for proteome scale drug-target identification.Commun Biol2020
32893496On-Chip Acousto Thermal Shift Assay for Rapid and Sensitive Assessment of Protein Thermodynamic Stability.Small2020
30642129Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-Based Antioxidant Strategies.Int J Mol Sci2019
31875562Intracellular Vesicle Fusion Requires a Membrane-Destabilizing Peptide Located at the Juxtamembrane Region of the v-SNARE.Cell Rep2019
31801276Flattening of Diluted Species Profile via Passive Geometry in a Microfluidic Device.Micromachines (Basel)2019
31387992Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways.Nat Commun2019
31227607Cryo-EM structure of OSCA1.2 from <i>Oryza sativa</i> elucidates the mechanical basis of potential membrane hyperosmolality gating.Proc Natl Acad Sci U S A2019
30317509Functional Reconstitution of Intracellular Vesicle Fusion Using Purified SNAREs and Sec1/Munc18 (SM) Proteins.Methods Mol Biol2019
30275014The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis.J Biol Chem2018
30127032SNARE zippering requires activation by SNARE-like peptides in Sec1/Munc18 proteins.Proc Natl Acad Sci U S A2018
28792968Identification of the primary peptide contaminant that inhibits fibrillation and toxicity in synthetic amyloid-β42.PLoS One2017
26874206Exosomes and other extracellular vesicles in neural cells and neurodegenerative diseases.Biochim Biophys Acta2016
26431309Reconstituting Intracellular Vesicle Fusion Reactions: The Essential Role of Macromolecular Crowding.J Am Chem Soc2015
26333660Architecture of the Synaptophysin/Synaptobrevin Complex: Structural Evidence for an Entropic Clustering Function at the Synapse.Sci Rep2015
24379376Self-assembled lipid and membrane protein polyhedral nanoparticles.Proc Natl Acad Sci U S A2014
23381628Coordinating the impact of structural genomics on the human α-helical transmembrane proteome.Nat Struct Mol Biol2013
20138128Loss of synaptotagmin IV results in a reduction in synaptic vesicles and a distortion of the Golgi structure in cultured hippocampal neurons.Neuroscience2010
20637753In vivo adsorption of autoantibodies in myasthenia gravis using Nanodisc-incorporated acetylcholine receptor.Exp Neurol2010
17327160Electron tomographic methods for studying the chemical synapse.Methods Cell Biol2007
17562317Structure of synaptophysin: a hexameric MARVEL-domain channel protein.Structure2007
16552147Rapid and simple protein-stability screens: application to membrane proteins.Acta Crystallogr D Biol Crystallogr2006
15339954Phylogenetic conservation of disulfide-linked, dimeric acetylcholine receptor pentamers in southern ocean electric rays.J Exp Biol2004
11242086GTPase activity of dynamin and resulting conformation change are essential for endocytosis.Nature2001
10559860Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring.Nat Cell Biol1999
10329178Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall.J Mol Biol1999
9818263Macromolecular structure determination by electron microscopy: new advances and recent results.Curr Opin Struct Biol1998
9631291The functional significance of multimerization in ion channels.Curr Opin Struct Biol1998
9063865Redox-dependent structural changes in the nitrogenase P-cluster.Biochemistry1997
9115209Light-induced structural changes in photosynthetic reaction center: implications for mechanism of electron-proton transfer.Science1997
9235936Electron paramagnetic resonance studies of succinate:ubiquinone oxidoreductase from Paracoccus denitrificans. Evidence for a magnetic interaction between the 3Fe-4S cluster and cytochrome b.J Biol Chem1997
9020789Uncompetitive substrate inhibition and noncompetitive inhibition by 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole (UHDBT) and 2-n-nonyl-4-hydroxyquinoline-N-oxide (NQNO) is observed for the cytochrome bo3 complex: implications for a Q(H2)-loop proton translocation mechanism.Biochemistry1997
8946850A leucine-rich repeat variant with a novel repetitive protein structural motif.Nat Struct Biol1996
7771322Structure and stability of membrane proteins.Adv Protein Chem1995
8644492Cytochrome c oxidase: chemistry of a molecular machine.Adv Enzymol Relat Areas Mol Biol1995
8378035Shedding light on the use of heat to treat HIV infections.Oncology1993
8253216Further comparison of ubiquinol and cytochrome c terminal oxidases.FEBS Lett1993
8392948Comparison of ubiquinol and cytochrome c terminal oxidases. An alternative view.FEBS Lett1993
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Collaborators

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Co-authored papers 6
Skidmore College
Co-authored papers 5
Skaggs School of Pharmacy and Pharmaceutical Sciences.
Co-authored papers 2
University of Colorado Anschutz Medical Campus
Co-authored papers 2
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Co-authored papers 2
University of Virginia
Co-authored papers 1
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Co-authored papers 1
Accelero Biostructures Inc.
Co-authored papers 1
Queen's University Belfast
Co-authored papers 1
University of California at San Diego
Co-authored papers 1
Jacobs School of Medicine and Biomedical Sciences, University of Buffalo
Co-authored papers 1
Technical University of Munich (TUM)
Co-authored papers 1
iHuman Institute, ShanghaiTech University
Co-authored papers 1
University of Colorado
Co-authored papers 1
Columbia University
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
University of Antwerp
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
University of Rochester Medical Center
Co-authored papers 1
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University of California San Francisco
Co-authored papers 1
NYU School of Medicine
Co-authored papers 1
Institute for Advanced Study (TUM-IAS), TUM (Technische Universitat Munchen)
Co-authored papers 1
Mayo Clinic Jacksonville
Co-authored papers 1
Biodesign Center for Applied Structural Discovery, Arizona State University
Co-authored papers 1
University of California san francisco
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University of Wisconsin-Madison
Co-authored papers 1