Author details

Full Name

Aaron F Carlin

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37096144	Neutralizing Antibody Responses After Severe Acute Respiratory Syndrome Coronavirus 2 BA.2 and BA.2.12.1 Infection Do Not Neutralize BA.4 and BA.5 and Can Be Blunted by Nirmatrelvir/Ritonavir Treatment.	Open Forum Infect Dis	2023
35723411	Virologic and Immunologic Characterization of Coronavirus Disease 2019 Recrudescence After Nirmatrelvir/Ritonavir Treatment.	Clin Infect Dis	2023
36907350	Human microglial models to study host-virus interactions.	Exp Neurol	2023
36753444	Protease-Responsive Potential-Tunable AIEgens for Cell Selective Imaging of TMPRSS2 and Accurate Inhibitor Screening.		2023
36747824	The lung employs an intrinsic surfactant-mediated inflammatory response for viral defense.	bioRxiv	2023
36804936	Identification of global inhibitors of cellular glycosylation.	Nat Commun	2023
36689652	PCIF1-mediated deposition of 5'-cap <i>N</i><sup>6</sup>,2'-<i>O</i>-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection.	Proc Natl Acad Sci U S A	2023
37040439	1-<i>O</i>-Octadecyl-2-<i>O</i>-benzyl-<i>sn</i>-glyceryl-3-<i>phospho</i>-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity.	J Med Chem	2023
35303432	Excess neuropeptides in lung signal through endothelial cells to impair gas exchange.	Dev Cell	2022
35973073	A Self-Immolative Fluorescent Probe for Selective Detection of SARS-CoV-2 Main Protease.	Anal Chem	2022
36097162	SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus.	Nat Commun	2022
35703437	Implementation of Practical Surface SARS-CoV-2 Surveillance in School Settings.	mSystems	2022
35703436	Sentinel Cards Provide Practical SARS-CoV-2 Monitoring in School Settings.	mSystems	2022
35878004	Protease-Responsive Peptide-Conjugated Mitochondrial-Targeting AIEgens for Selective Imaging and Inhibition of SARS-CoV-2-Infected Cells.	ACS Nano	2022
35931732	Conformational flexibility in neutralization of SARS-CoV-2 by naturally elicited anti-SARS-CoV-2 antibodies.	Communications Biology	2022
35862442	Structure-selected RBM immunogens prime polyclonal memory responses that neutralize SARS-CoV-2 variants of concern.	PLoS Pathogens	2022
35611335	Virologic and Immunologic Characterization of COVID-19 Recrudescence after Nirmatrelvir/Ritonavir Treatment.	Res Sq	2022
36560827	In Vitro Diagnostic Assay to Detect SARS-CoV-2-Neutralizing Antibody in Patient Sera Using Engineered ACE-2 Mini-Protein.		2022
35313591	Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions.	Res Sq	2022
34570513	Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors.	J Med Chem	2022
35233578	Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions.	bioRxiv	2022
34889013	A Dual-Color Fluorescent Probe Allows Simultaneous Imaging of Main and Papain-like Proteases of SARS-CoV-2-Infected Cells for Accurate Detection and Rapid Inhibitor Screening.	Angew Chem Int Ed Engl	2022
35076277	Decoding Transcription Regulatory Mechanisms Associated with <i>Coccidioides immitis</i> Phase Transition Using Total RNA.	mSystems	2022
34726486	Analysis of SARS-CoV-2 RNA Persistence across Indoor Surface Materials Reveals Best Practices for Environmental Monitoring Programs.	mSystems	2021
34067070	Transcriptional Analysis of <i>Coccidioides immitis</i> Mycelia and Spherules by RNA Sequencing.	J Fungi (Basel)	2021
33961823	METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection.	Cell Rep	2021
33743492	Hitting the diagnostic sweet spot: Point-of-care SARS-CoV-2 salivary antigen testing with an off-the-shelf glucometer.	Biosensors and Bioelectronics	2021
33631122	Revealing Tissue-Specific SARS-CoV-2 Infection and Host Responses using Human Stem Cell-Derived Lung and Cerebral Organoids.	Stem Cell Reports	2021
34003853	Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity.	PLoS Pathog	2021
33791697	The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection.	bioRxiv	2021
33787221	A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells.	ACS Chem Biol	2021
33571304	Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors.	PLoS Pathogens	2021
33936671	Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib.	Clin Case Rep	2021
34312621	Comparison of heat-inactivated and infectious SARS-CoV-2 across indoor surface materials shows comparable RT-qPCR viral signal intensity and persistence.	bioRxiv	2021
34310217	Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs.	Antimicrobial Agents and Chemotherapy	2021
34244682	A human three-dimensional neural-perivascular 'assembloid' promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology.	Nat Med	2021
33594369	A Human 3D neural assembloid model for SARS-CoV-2 infection.	bioRxiv	2021
33594354	A Human 3D neural assembloid model for SARS-CoV-2 infection.	Res Sq	2021
34407940	Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity.	Science advances	2021
34401413	Dataset on optimization and development of a point-of-care glucometer-based SARS-CoV-2 detection assay using aptamers.	Data in Brief	2021
34672530	Cowpea Mosaic Virus Nanoparticle Vaccine Candidates Displaying Peptide Epitopes Can Neutralize the Severe Acute Respiratory Syndrome Coronavirus.	ACS Infectious Diseases	2021
33052341	Multi-Clonal Live SARS-CoV-2 In Vitro Neutralization by Antibodies Isolated from Severe COVID-19 Convalescent Donors.		2020
32473127	Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals.	Cell	2020
32699853	SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.	bioRxiv	2020
33140046	A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells.	bioRxiv	2020
32944968	Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol.	EMBO J	2020
33106296	Interleukin-8 Receptor 2 (IL-8R2)-Deficient Mice Are More Resistant to Pulmonary Coccidioidomycosis than Control Mice.	Infection and Immunity	2020
30576956	Genome-wide approaches to unravelling host-virus interactions in Dengue and Zika infections.	Current Opinion in Virology	2019
30226150	Case Report: A Common Source Outbreak of Anisakidosis in the United States and Postexposure Prophylaxis of Family Collaterals.	Am J Trop Med Hyg	2018
30596671	A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected while traveling to Caracas, Venezuela.	PLoS Negl Trop Dis	2018