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Author Details

Loren L Looger
Howard Hughes Medical Institute
1994
145
66
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36811153Fast and sensitive GCaMP calcium indicators for neuronal imaging.J Physiol2024
37787057Extracellular glutamate and GABA transients at the transition from interictal spiking to seizures.Brain2024
36424433Ketamine triggers a switch in excitatory neuronal activity across neocortex.Nat Neurosci2023
37546883A Non-Coding Variant in <i>SLC15A4</i> Modulates Enhancer Activity and Lysosomal Deacidification Linked to Lupus Susceptibility.bioRxiv2023
37292710Multicore fiber optic imaging reveals that astrocyte calcium activity in the cerebral cortex is modulated by internal motivational state.bioRxiv2023
37333331Direct measurement of dynamic attractant gradients reveals breakdown of the Patlak-Keller-Segel chemotaxis model.bioRxiv2023
37066327A multilayered post-GWAS analysis pipeline defines functional variants and target genes for systemic lupus erythematosus (SLE).medRxiv2023
36922596Fast and sensitive GCaMP calcium indicators for imaging neural populations.Nature2023
36868853Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane.J Neurosci2023
34982029Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands.Elife2022
35741778Discovery and Functional Characterization of Two Regulatory Variants Underlying Lupus Susceptibility at 2p13.1.Genes (Basel)2022
35778397Many dissimilar NusG protein domains switch between α-helix and β-sheet folds.Nat Commun2022
35446570Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids.J Am Chem Soc2022
36520038Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands.Elife2022
36532688Fluorescence Screens for Identifying Central Nervous System-Acting Drug-Biosensor Pairs for Subcellular and Supracellular Pharmacokinetics.Bio Protoc2022
36324510Genome-wide association study for systemic lupus erythematosus in an egyptian population.Front Genet2022
36344833Chemically stable fluorescent proteins for advanced microscopy.Nat Methods2022
33462801A high-throughput predictive method for sequence-similar fold switchers.Biopolymers2021
33607281Evaluation of multi-color genetically encoded Ca<sup>2+</sup> indicators in filamentous fungi.Fungal Genet Biol2021
34498740A sequence-based method for predicting extant fold switchers that undergo α-helix ⿿ β-strand transitions.Biopolymers2021
34161775In vivo glucose imaging in multiple model organisms with an engineered single-wavelength sensor.Cell Rep2021
33982894Lupus Susceptibility Region Containing CDKN1B rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis.Arthritis Rheumatol2021
34117238The functional organization of excitatory synaptic input to place cells.Nat Commun2021
32396366Nanoscopic Visualization of Restricted Nonvolume Cholinergic and Monoaminergic Transmission with Genetically Encoded Sensors.Nano Lett2020
31900346The neuropeptide Drosulfakinin regulates social isolation-induced aggression in Drosophila.J Exp Biol2020
33174843Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells.Elife2020
32299951Temperature-dependent sex determination is mediated by pSTAT3 repression of <i>Kdm6b</i>.Science2020
30718376Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors.J Gen Physiol2019
31798415Biosensors Show the Pharmacokinetics of S-Ketamine in the Endoplasmic Reticulum.Front Cell Neurosci2019
31562479Voices in methods development.Nat Methods2019
31388143Author Correction: Kilohertz frame-rate two-photon tomography.Nat Methods2019
31209382High-performance calcium sensors for imaging activity in neuronal populations and microcompartments.Nat Methods2019
31230713Glia Accumulate Evidence that Actions Are Futile and Suppress Unsuccessful Behavior.Cell2019
31308547A genetically encoded fluorescent sensor for in vivo imaging of GABA.Nat Methods2019
31564455Single-Cell Reconstruction of Emerging Population Activity in an Entire Developing Circuit.Cell2019
31363222Kilohertz frame-rate two-photon tomography.Nat Methods2019
30926781Multiplex imaging relates quantal glutamate release to presynaptic Ca<sup>2+</sup> homeostasis at multiple synapses in situ.Nat Commun2019
31148305Inaccurate secondary structure predictions often indicate protein fold switching.Protein Sci2019
31164884Mechanistic Characterization of <i>RASGRP1</i> Variants Identifies an hnRNP-K-Regulated Transcriptional Enhancer Contributing to SLE Susceptibility.Front Immunol2019
30820033Author Correction: Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR.Nat Methods2019
30755613A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP.Nat Commun2019
31106909Quantitative in vivo imaging of neuronal glucose concentrations with a genetically encoded fluorescence lifetime sensor.J Neurosci Res2019
31022184Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians.PLoS Genet2019
29784778Extant fold-switching proteins are widespread.Proc Natl Acad Sci U S A2018
29996097Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model.Cell Rep2018
30377363Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR.Nat Methods2018
30382200Distinct descending motor cortex pathways and their roles in movement.Nature2018
30382198Shared and distinct transcriptomic cell types across neocortical areas.Nature2018
29618589Functional Imaging and Optogenetics in <i>Drosophila</i>.Genetics2018
27861906All-optical functional synaptic connectivity mapping in acute brain slices using the calcium integrator CaMPARI.J Physiol2017
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Collaborators

John B Harley
US Department of Veterans Affairs Medical Center
Co-authored papers 6
Yukinori Okada
Osaka University School of Medicine Graduate School of Medicine
Co-authored papers 5
Joel M Guthridge
Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation
Co-authored papers 3
Xiaowei Zhuang
Howard Hughes Medical Institute, Harvard University
Co-authored papers 3
Hongkui Zeng
Allen Institute for Brain Science
Co-authored papers 3
Julie H Simpson
Co-authored papers 2
Bruce E Kimmel
Howard Hughes Medical Institute, University of California berkeley
Co-authored papers 2
Bok-Ghee Han
Co-authored papers 2
Quan-Zhen Li
Co-authored papers 2
Zizhen Yao
Allen Institute for Brain Science
Co-authored papers 2
Anirudh Natarajan
University of California at Berkeley
Co-authored papers 2
Kathy L Moser
Co-authored papers 2
Edward S Boyden
McGovern Institute for Brain Research
Co-authored papers 2
Brett D Mensh
Howard Hughes Medical Institute
Co-authored papers 2
Lily Yeh Jan
Co-authored papers 2
Patrick M Gaffney
Co-authored papers 2
Alex K Shalek
Institute for Medical Engineering & Science, Massachusetts Institute of Technology
Co-authored papers 1
Nicholas J Sofroniew
Co-authored papers 1
Guoping Feng
Co-authored papers 1
Carl D Langefeld
Wake Forest University School of Medicine
Co-authored papers 1
Susumu Tomita
Co-authored papers 1
Michael Hawrylycz
Allen Institute for Brain Science
Co-authored papers 1
Clifford P Brangwynne
Lewis-Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 1
Young Jin Kim
Co-authored papers 1
Nancy J Olsen
Co-authored papers 1
Eric A Bushong
University of California San Diego (university of california san diego)
Co-authored papers 1
Thomas A Neubert
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 1
Polina Anikeeva
Massachusetts Institute of Technology
Co-authored papers 1
Qingming Luo
Hainan University
Co-authored papers 1
Olga G Troyanskaya
Lewis-Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 1
Release 1.2