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Author Details

David L Wiest
Fox Chase Cancer Center
1986
123
41
PMIDPaper TitleJournal TitlePublished Year
37871574Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1-mediated immune suppression during GVHD.Blood2024
36374451Development of γδ T Cells: Soldiers on the Front Lines of Immune Battles.Methods Mol Biol2023
37620604Doubling down to make killer T cells.Nat Immunol2023
37443284Transcription factor EGR2 controls homing and pathogenicity of T<sub>H</sub>17 cells in the central nervous system.Nat Immunol2023
37398007Ribosomal protein control of hematopoietic stem cell transformation through direct, non-canonical regulation of metabolism.bioRxiv2023
36374469Zebrafish: A Tractable Model for Analysis of T Cell Development.Methods Mol Biol2023
35046107Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis.J Immunol2022
35436326The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm.Blood2022
35723626IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma.Cancer Discov2022
35967429Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency.Front Immunol2022
36202870Loss of Zfp335 triggers cGAS/STING-dependent apoptosis of post-β selection thymocytes.Nat Commun2022
34107257Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo.Cell Rep2021
33535043The E protein-TCF1 axis controls γδ T cell development and effector fate.Cell Rep2021
34887873A Novel Germline Heterozygous <i>BCL11B</i> Variant Causing Severe Atopic Disease and Immune Dysregulation.Front Immunol2021
32399190Recent advances in understanding the development and function of γδ T cells.F1000Res2020
32579914NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma.Cell Rep2020
31581233RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance.PLoS One2019
29432160Role of a selecting ligand in shaping the murine γδ-TCR repertoire.Proc Natl Acad Sci U S A2018
30012846Id3 Restricts γδ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity.J Immunol2018
30344933Gadd45 stress sensors in suppression of leukemia.Oncotarget2018
30333627Functional genomic landscape of acute myeloid leukaemia.Nature2018
29754419Integration of T-cell receptor, Notch and cytokine signals programs mouse γδ T-cell effector differentiation.Immunol Cell Biol2018
29615510Reply to Chien: Clarification of the effect of ligand on γδ-TCR repertoire selection.Proc Natl Acad Sci U S A2018
28076796Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing.Cell Rep2017
28122332The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling.Oncotarget2017
28323266THEMIS-tery is solved.Nat Immunol2017
29127144Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in <i>ARPC1B</i>.J Immunol2017
28938112Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.Cell2017
29222418HEB is required for the specification of fetal IL-17-producing γδ T cells.Nat Commun2017
27840425JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia.Leukemia2017
27432940Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects.J Exp Med2016
26294415Using the Zebrafish Model to Study T Cell Development.Methods Mol Biol2016
26294395Development of γδ T Cells, the Special-Force Soldiers of the Immune System.Methods Mol Biol2016
26445298Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts.J Cell Physiol2016
27959755Multisystem Anomalies in Severe Combined Immunodeficiency with Mutant BCL11B.N Engl J Med2016
27197267The BRCA1-ο11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.Cancer Res2016
27197189Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma.Cancer Res2016
27489283Rpl22 Loss Selectively Impairs αβ T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling.J Immunol2016
25416806Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint.J Immunol2015
26853850Regulatory Roles of Rpl22 in Hematopoiesis: An Old Dog with New Tricks.Crit Rev Immunol2015
26161877Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.PLoS One2015
24493796The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification.J Exp Med2014
25526308Noncanonical mode of ERK action controls alternative αβ and γδ T cell lineage fates.Immunity2014
25326547Origins of γδ T cell effector subsets: a riddle wrapped in an enigma.J Immunol2014
24935715Fli-1 regulates the DN2 to DN3 thymocyte transition and promotes γδ T-cell commitment by enhancing TCR signal strength.Eur J Immunol2014
24706811Enforcement of γδ-lineage commitment by the pre-T-cell receptor in precursors with weak γδ-TCR signals.Proc Natl Acad Sci U S A2014
23355739A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes.J Immunol2013
23990801The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1.PLoS Genet2013
23449473Control of hematopoietic stem cell emergence by antagonistic functions of ribosomal protein paralogs.Dev Cell2013
22357628Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling.J Immunol2012
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Collaborators

Suraj Peri
Co-authored papers 9
Michele K Anderson
Sunnybrook Research Institute, University of Toronto
Co-authored papers 4
Roland L Dunbrack
Fox Chase Cancer Center
Co-authored papers 4
Denise C Connolly
Fox Chase Cancer Center
Co-authored papers 3
Billy Truong
Fox Chase Cancer Center
Co-authored papers 2
Cornelis Murre
University of California
Co-authored papers 2
Jeffrey W Tyner
Oregon Health & Science University School of Medicine
Co-authored papers 2
Steven E Brenner
University of California berkeley
Co-authored papers 2
Nicola Long
Oregon Health and Science University
Co-authored papers 1
Jason D MacManiman
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 1
Javier Ben??tez
Instituto de Salud Carlos III
Co-authored papers 1
Jos Jonkers
Oncode Institute, Netherlands Cancer Institute
Co-authored papers 1
Kathleen M Fisch
Center for Computational Biology and Bioinformatics, University of California
Co-authored papers 1
Melissa L Abel
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Aurora S Blucher
Knight Cancer Institute, Oregon Health Sciences University
Co-authored papers 1
Jessica Leonard
Oregon Health & Science University
Co-authored papers 1
Brian J Druker
Oregon Health & Science University
Co-authored papers 1
Justin M Watts
University of Miami, Sylvester Comprehensive Cancer Center
Co-authored papers 1
Pierrette Lo
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Aashis Thapa
Emory School of Medicine
Co-authored papers 1
Russell T Burke
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Abdusebur Jemal
Morehouse School of Medicine
Co-authored papers 1
Joshua D Milner
Columbia University
Co-authored papers 1
Amanda d'Almeida
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Ryan M Winters
Fox Chase Cancer Center
Co-authored papers 1
Cristina E Tognon
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
James Dibb
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Haijiao Zhang
Oregon Health & Science University, Knight Cancer Institute
Co-authored papers 1
Simon Melov
Buck Institute for Research on Aging
Co-authored papers 1
Elie Traer
Oregon Health & Science University
Co-authored papers 1
Release 1.2