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Author Details

Donald M Bers
1979
506
111
PMIDPaper TitleJournal TitlePublished Year
36662864Whole-heart multiparametric optical imaging reveals sex-dependent heterogeneity in cAMP signaling and repolarization kinetics.2023
37662205Nitric Oxide modulates spontaneous Ca release and ventricular arrhythmias during β-adrenergic signalling through -nitrosylation of Calcium/Calmodulin dependent kinase II.2023
37976157MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle.2023
37628726Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State.2023
37555352SparkMaster 2: A New Software for Automatic Analysis of Calcium Spark Data.2023
37961889Nitric Oxide Modulates Ca Leak and Arrhythmias via S-Nitrosylation of CaMKII.2023
37149124Cardiac Protein Kinase D1 ablation alters the myocytes β-adrenergic response.2023
36708951Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT.2023
37461514Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State.2023
36744541Diversity of cells and signals in the cardiovascular system.J Physiol2023
36607801New cardiac targets for empagliflozin: -GlcNAcylation, CaMKII, and calcium handling.2023
35344407Empagliflozin Reverses Late Na Current Enhancement and Cardiomyocyte Proarrhythmia in a Translational Murine Model of Heart Failure With Preserved Ejection Fraction.Circulation2022
36172952Protein Kinase D1 Regulates Cardiac Hypertrophy, Potassium Channel Remodeling, and Arrhythmias in Heart Failure.Journal of the American Heart Association2022
36227145Nitrosylation of cardiac CaMKII at Cys290 mediates mechanical afterload-induced increases in Ca transient and Ca sparks.Journal of Physiology2022
36345826Spatiotemporal Control of Vascular Ca1.2 by α1 S1928 Phosphorylation.Circulation Research2022
35620477Subcellular Propagation of Cardiomyocyte β-Adrenergic Activation of Calcium Uptake Involves Internal β-Receptors and AKAP7.2022
35405106Synergistic FRET assays for drug discovery targeting RyR2 channels.Journal of Molecular and Cellular Cardiology2022
36416174Diabetes and Excess Aldosterone Promote Heart Failure With Preserved Ejection Fraction.Journal of the American Heart Association2022
36189813Functional remodelling of perinuclear mitochondria alters nucleoplasmic Ca signalling in heart failure.Philosophical Transactions of the Royal Society B: Biological Sciences2022
35050687Neuron-Restrictive Silencer Factor Limits Myocyte Gα Expression and Is Protective in Heart Failure Progression.Circulation Research2022
34793835Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening.Journal of Biological Chemistry2022
34814703AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR.Circulation Research2022
34472381Cardiac Na/Ca Exchange Suppression: A Late-Breaking Knockout Story Showing That There Is No Free Lunch.Journal of the American Heart Association2021
33593074Loss of CASK Accelerates Heart Failure Development.Circulation Research2021
33590335CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes.Basic Research in Cardiology2021
33483728Two-hit mechanism of cardiac arrhythmias in diabetic hyperglycaemia: reduced repolarization reserve, neurohormonal stimulation, and heart failure exacerbate susceptibility.Cardiovascular Research2021
33963531Increasing SERCA function promotes initiation of calcium sparks and breakup of calcium waves.Journal of Physiology2021
34045974Role of Reduced Sarco-Endoplasmic Reticulum Ca-ATPase Function on Sarcoplasmic Reticulum Ca Alternans in the Intact Rabbit Heart.Frontiers in Physiology2021
34149440PK11195 Protects From Cell Death Only When Applied During Reperfusion: Succinate-Mediated Mechanism of Action.Frontiers in Physiology2021
33601939Mechanical Load Regulates Excitation-Ca Signaling-Contraction in Cardiomyocyte.Circulation Research2021
33926209CaMKII Serine 280 O-GlcNAcylation Links Diabetic Hyperglycemia to Proarrhythmia.Circulation Research2021
34326268Mechanoelectric coupling and arrhythmogenesis in cardiomyocytes contracting under mechanical afterload in a 3D viscoelastic hydrogel.Proceedings of the National Academy of Sciences of the United States of America2021
33375812Inositol Trisphosphate Receptors and Nuclear Calcium in Atrial Fibrillation.Circulation Research2021
33183171Intracellular β-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility.Circulation Research2021
33334123JNK2, a Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca] Leak-Load Relationship.Circulation Research2021
34648073Cardiomyocyte Na and Ca mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors.Basic Research in Cardiology2021
34371035CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes.Journal of Molecular and Cellular Cardiology2021
34530626Monoamine Oxidases Desensitize Intracellular βAR Signaling in Heart Failure.Circulation Research2021
34583524Ketone Ester D-β-Hydroxybutyrate-(R)-1,3 Butanediol Prevents Decline in Cardiac Function in Type 2 Diabetic Mice.Journal of the American Heart Association2021
33433005α-Actinin-1 promotes activity of the L-type Ca channel Ca1.2.EMBO Journal2020
32202931Balance Between Rapid Delayed Rectifier K Current and Late Na Current on Ventricular Repolarization: An Effective Antiarrhythmic Target?Circulation: Arrhythmia and Electrophysiology2020
32134364Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species via -linked GlcNAcylation and CaMKII Activation in Mouse Ventricular Myocytes.Circulation Research2020
32019969RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca assays.Scientific Reports2020
31739987Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries.Kidney International2020
31789427Mechano-electric and mechano-chemo-transduction in cardiomyocytes.Journal of Physiology2020
32299299MCUb Induction Protects the Heart From Postischemic Remodeling.Circulation Research2020
31998965Mechanics and energetics in cardiac arrhythmias and heart failure.Journal of Physiology2020
31985069α-Actinin-1 promotes activity of the L-type Ca channel Ca 1.2.EMBO Journal2020
32454061A 20/20 view of ANT function in mitochondrial biology and necrotic cell death.Journal of Molecular and Cellular Cardiology2020
32821022CaMKIIδC Drives Early Adaptive Ca<sup>2+</sup> Change and Late Eccentric Cardiac Hypertrophy.Circ Res2020
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and Center for Structural Biology, Vanderbilt University
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University of Alabama at Birmingham
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Boston Children's Hospital and Harvard Medical School
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Center for Advanced Medical Analytics, University of Virginia School of Medicine
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