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Author Details

Sara A Courtneidge
Oregon Health & Science University
1977
130
68
PMIDPaper TitleJournal TitlePublished Year
35428815Megakaryocytes form linear podosomes devoid of digestive properties to remodel medullar matrix.Sci Rep2022
33414172Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5α Promotes Cancer Invasion and Tumor Growth.Cancer Res2021
33070041Crosstalk between invadopodia and the extracellular matrix.Eur J Cell Biol2020
28548369Invadosomes are coming: new insights into function and disease relevance.FEBS J2018
30214939Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival.Sci Adv2018
29856687Induction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models.Cancer Biol Ther2018
29311151Tks adaptor proteins at a glance.J Cell Sci2018
29263157SRC Increases <i>MYC</i> mRNA Expression in Estrogen Receptor-Positive Breast Cancer via mRNA Stabilization and Inhibition of p53 Function.Mol Cell Biol2018
28468988ADAM12 induction by Twist1 promotes tumor invasion and metastasis via regulation of invadopodia and focal adhesions.J Cell Sci2017
27802184The role of Tks adaptor proteins in invadopodia formation, growth and metastasis of melanoma.Oncotarget2016
25826475The invadopodia scaffold protein Tks5 is required for the growth of human breast cancer cells in vitro and in vivo.PLoS One2015
24174371Src-dependent Tks5 phosphorylation regulates invadopodia-associated invasion in prostate cancer cells.Prostate2014
25259869Genetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5.PLoS One2014
25176655Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis.Cell Rep2014
24714597Regulation of invadopodia by the tumor microenvironment.Cell Adh Migr2014
23589494Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia.J Cell Biol2013
22033009Redox signaling at invasive microdomains in cancer cells.Free Radic Biol Med2012
22461640Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma.Sci Transl Med2012
22238358Fer kinase regulates cell migration through α-dystroglycan glycosylation.Mol Biol Cell2012
22260678Cell migration and invasion in human disease: the Tks adaptor proteins.Biochem Soc Trans2012
21328520Podosomal proteins as causes of human syndromes: a role in craniofacial development?Genesis2011
21799874A Src-Tks5 pathway is required for neural crest cell migration during embryonic development.PLoS One2011
21791703A cell-based high-content screening assay reveals activators and inhibitors of cancer cell invasion.Sci Signal2011
21697900The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function.Nat Rev Mol Cell Biol2011
20351064MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro.J Cell Biol2010
20137777Disruption of the podosome adaptor protein TKS4 (SH3PXD2B) causes the skeletal dysplasia, eye, and cardiac abnormalities of Frank-Ter Haar Syndrome.Am J Hum Genet2010
19144821The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation.Mol Biol Cell2009
19596797Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.J Cell Sci2009
19755710Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity.Sci Signal2009
19755709Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation.Sci Signal2009
19816508The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease.Cell Death Differ2009
19540230Tks5 recruits AFAP-110, p190RhoGAP, and cortactin for podosome formation.Exp Cell Res2009
18417249A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo.Eur J Cell Biol2008
18794076The Translational Research Working Group developmental pathway for anticancer agents (drugs or biologics).Clin Cancer Res2008
18463161The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.Mol Biol Cell2008
18337078Assembly and biological role of podosomes and invadopodia.Curr Opin Cell Biol2008
15710328The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells.Cancer Cell2005
16869750The SRC substrate Tks5, podosomes (invadopodia), and cancer cell invasion.Cold Spring Harb Symp Quant Biol2005
15637050Platelet-derived growth factor stimulates Src-dependent mRNA stabilization of specific early genes in fibroblasts.J Biol Chem2005
15489913The interplay between Src family kinases and receptor tyrosine kinases.Oncogene2004
12508108The multi-adaptor proto-oncoprotein Cbl is a key regulator of Rac and actin assembly.J Cell Sci2003
12615925The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells.J Biol Chem2003
12712187Cancer: Escape from inhibition.Nature2003
12514095The ADAMs family of metalloproteases: multidomain proteins with multiple functions.Genes Dev2003
12511554Src family kinases are involved in the differential signaling from two splice forms of c-Kit.J Biol Chem2003
12546647Isolation of novel Src substrates.Biochem Soc Trans2003
12023816Role of Src in signal transduction pathways. The Jubilee Lecture.Biochem Soc Trans2002
11404481Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis.Proc Natl Acad Sci U S A2001
10623460Src family tyrosine kinases and growth factor signaling.Exp Cell Res2000
10851090No requirement for src family kinases for PDGF signaling in fibroblasts expressing SV40 large T antigen.Oncogene2000
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Collaborators

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Oregon Health & Science University, University of California Berkeley
Co-authored papers 2
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Co-authored papers 1
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Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Oregon Health and Science University
Co-authored papers 1
City of Hope National Medical Center
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University of California at Davis
Co-authored papers 1
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Knight Cancer Institute, Oregon Health & Science University
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Knight Cancer Institute, Oregon Health and Science University
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Oregon Health & Science University
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