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Author Details

Michaela Nathrath
1991
89
30
PMIDPaper TitleJournal TitlePublished Year
37584291Spontaneous remission and loss of monosomy 7: a window of opportunity for young children with SAMD9L syndrome.Haematologica2024
36586540Constitutional Microsatellite Instability, Genotype, and Phenotype Correlations in Constitutional Mismatch Repair Deficiency.Gastroenterology2023
37931683Osteosarcomas With Few Chromosomal Alterations or Adult Onset Are Genetically Heterogeneous.2023
38010733Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway.2023
37628315Telehealth Needs and Concerns of Stakeholders in Pediatric Palliative Home Care.2023
37548393Solitary pulmonary metastases at first recurrence of osteosarcoma: Presentation, treatment, and survival of 219 patients of the Cooperative Osteosarcoma Study Group.2023
37159273Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors.2023
35347251Methylation and copy number profiling: emerging tools to differentiate osteoblastoma from malignant mimics?Modern Pathology2022
35698215Integrative medicine during the intensive phase of chemotherapy in pediatric oncology in Germany: a randomized controlled trial with 5-year follow up.BMC Cancer2022
35802025FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits.Cancer Res2022
36575299Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM.NPJ Precis Oncol2022
34762643DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma.PLoS Comput Biol2021
32179705Germline <i>RET</i> variants underlie a subset of paediatric osteosarcoma.J Med Genet2021
33963544The early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies.J Pathol2021
33084925[Erratum to: DKG certification of paediatric cancer centres - a wide field ⿦].Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz2021
33295144Overactivation of the IGF signalling pathway in osteosarcoma: a potential therapeutic target?J Pathol Clin Res2021
34373263The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets.Cancer Discov2021
31431735Genotyping circulating tumor DNA of pediatric Hodgkin lymphoma.Leukemia2020
32022484NTRK fusions in osteosarcoma are rare and non-functional events.J Pathol Clin Res2020
32362894Vaccination With Live Attenuated Vaccines in Four Children With Chronic Myeloid Leukemia While on Imatinib Treatment.Front Immunol2020
31928458Pathological Fracture and Prognosis of High-Grade Osteosarcoma of the Extremities: An Analysis of 2,847 Consecutive Cooperative Osteosarcoma Study Group (COSS) Patients.J Clin Oncol2020
31494577High-sensitivity microsatellite instability assessment for the detection of mismatch repair defects in normal tissue of biallelic germline mismatch repair mutation carriers.Journal of Medical Genetics2020
30740824A sensitive and scalable microsatellite instability assay to diagnose constitutional mismatch repair deficiency by sequencing of peripheral blood leukocytes.Hum Mutat2019
31738425Rapid, complete and sustained tumour response to the TRK inhibitor larotrectinib in an infant with recurrent, chemotherapy-refractory infantile fibrosarcoma carrying the characteristic ETV6-NTRK3 gene fusion.Annals of Oncology2019
32223937Rapid, complete and sustained tumour response to the TRK inhibitor larotrectinib in an infant with recurrent, chemotherapy-refractory infantile fibrosarcoma carrying the characteristic ETV6-NTRK3 gene fusion.Annals of Oncology2019
30549028Activating mutations in the MAP-kinase pathway define non-ossifying fibroma of bone.J Pathol2019
29755686Transcriptome based individualized therapy of refractory pediatric sarcomas: feasibility, tolerability and efficacy.Oncotarget2018
30013564No Overt Clinical Immunodeficiency Despite Immune Biological Abnormalities in Patients With Constitutional Mismatch Repair Deficiency.Front Immunol2018
29489754The landscape of genomic alterations across childhood cancers.Nature2018
28168833Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.Am J Med Genet A2017
28494505Genome-wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma.International Journal of Cancer2017
29152092The long non-coding RNA is associated with and the absence of FRA16D breakage in osteosarcoma patients.Oncotarget2017
27447864Osteosarcoma cells with genetic signatures of BRCAness are susceptible to the PARP inhibitor talazoparib alone or in combination with chemotherapeutics.Oncotarget2017
28196983Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis.Leukemia2017
27569442Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial.Lancet Oncol2016
27099149Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome.Blood2016
27315524The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report.Clin Sarcoma Res2016
27479119Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study.Eur J Cancer2016
26632267Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency.Nat Commun2015
25848766Genomic heterogeneity of osteosarcoma - shift from single candidates to functional modules.PLoS One2015
25672644Disseminated oligodendroglial-like leptomeningeal tumors: preliminary diagnostic and therapeutic results for a novel tumor entity [corrected].Journal of Neuro-Oncology2015
25762628TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome.Oncotarget2015
26039064New small molecules targeting apoptosis and cell viability in osteosarcoma.PLoS One2015
26037465Erratum to: Disseminated oligodendroglial-like leptomeningeal tumors: preliminary diagnostic and therapeutic results for a novel tumor entity.Journal of Neuro-Oncology2015
24955218Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma - reasons and consequences.Genes and Cancer2014
24246156Osteosarcomas of the jaws differ from their peripheral counterparts and require a distinct treatment approach. Experiences from the DOESAK Registry.Oral Oncology2014
24417819Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.Gastroenterology2014
24865352Structuring osteosarcoma knowledge: an osteosarcoma-gene association database based on literature mining and manual annotation.Database (Oxford)2014
25092376A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice.Molecular Cancer2014
23169501Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1-specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantation.Journal of Clinical Oncology2013
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Technische Universitat Munchen
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Hopp Children's Cancer Center Heidelberg (KiTZ)
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University Hospital Essen, West German Cancer Center
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Hopp Children's Cancer Center Heidelberg (KiTZ)
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Institutet of Bioinformatics, University Hospital of Munster, University of Munster
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University Hospital Erlangen
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Hopp Children's Cancer Center Heidelberg (KiTZ)
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Clinical Trials Unit
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German Cancer Research Center (DKFZ)
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Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf
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