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Author Details

Alister G Craig
Malawi-Liverpool-Wellcome Trust Clinical Research Program
1987
130
44
PMIDPaper TitleJournal TitlePublished Year
36864926Pf7: an open dataset of <i>Plasmodium falciparum</i> genome variation in 20,000 worldwide samples.Wellcome Open Res2023
38033133Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture.PLoS One2023
37141324Plasmodium falciparum-infected erythrocyte co-culture with the monocyte cell line THP-1 does not trigger production of soluble factors reducing brain microvascular barrier function.PLoS One2023
32845969How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria?J Infect Dis2022
35691772Austral birds offer insightful complementary models in ecology and evolution.Trends Ecol Evol2022
36211953Editorial: Models to study malaria parasite-host interactions and pathogenesis.Front Cell Infect Microbiol2022
35881372Static Adhesion of Plasmodium falciparum-Infected Erythrocytes to Purified and Recombinant Receptors.Methods Mol Biol2022
34246628Functionalized supported membranes for quantifying adhesion of P. falciparum-infected erythrocytes.Biophys J2021
34802442Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine.BMC Med2021
32409404Parasite histones mediate blood-brain barrier disruption in cerebral malaria.Clin Med (Lond)2020
32029768Developing a xenograft model of human vasculature in the mouse ear pinna.Sci Rep2020
32579667Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria.Blood Adv2020
30610112Cerebral malaria is associated with differential cytoadherence to brain endothelial cells.EMBO Mol Med2019
31527263Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum-infected erythrocytes.Proc Natl Acad Sci U S A2019
31396236Comparison of CD8<sup>+</sup> T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria.Front Immunol2019
29459671In silico guided reconstruction and analysis of ICAM-1-binding var genes from Plasmodium falciparum.Sci Rep2018
30103779Comparative 1D Blue-Native electrophoresis analysis of Plasmodium falciparum and human proteins associated with cytoadherence.Malar J2018
29954866Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria.Proc Natl Acad Sci U S A2018
29635016Brain microvascular endothelial-astrocyte cell responses following Japanese encephalitis virus infection in an in vitro human blood-brain barrier model.Mol Cell Neurosci2018
29578406Neurovascular sequestration in paediatric <i>P. falciparum</i> malaria is visible clinically in the retina.Elife2018
29662697Supporting capacity for research on malaria in Africa.BMJ Glob Health2018
28679447In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36.Malar J2017
28481947Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner.PLoS Negl Trop Dis2017
28273147A quantitative brain map of experimental cerebral malaria pathology.PLoS Pathog2017
29045442A semi-synthetic glycosaminoglycan analogue inhibits and reverses Plasmodium falciparum cytoadherence.PLoS One2017
26893139An external sensing system in Plasmodium falciparum-infected erythrocytes.Malar J2016
26511133A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria.Blood2016
27643435Breaking down brain barrier breaches in cerebral malaria.J Clin Invest2016
27899115Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi.Malar J2016
27311750HIV coinfection influences the inflammatory response but not the outcome of cerebral malaria in Malawian children.J Infect2016
26766771Marked elevation in plasma osteoprotegerin constitutes an early and consistent feature of cerebral malaria.Thromb Haemost2016
26849362Correction: An Analysis of the Binding Characteristics of a Panel of Recently Selected ICAM-1 Binding Plasmodium falciparum Patient Isolates.PLoS One2016
27080559Tumor necrosis factor reduces Plasmodium falciparum growth and activates calcium signaling in human malaria parasites.Biochim Biophys Acta2016
25351204Severity of retinopathy parallels the degree of parasite sequestration in the eyes and brains of malawian children with fatal cerebral malaria.J Infect Dis2015
26431986Workshop report: Malaria vaccine development in Europe--preparing for the future.Vaccine2015
25482886Investigating the function of Fc-specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting.Cell Microbiol2015
24048963Persistent endothelial activation and inflammation after Plasmodium falciparum Infection in Malawian children.J Infect Dis2014
25473835Differential PfEMP1 expression is associated with cerebral malaria pathology.PLoS Pathog2014
25120958Pathogenesis of cerebral malaria--inflammation and cytoadherence.Front Cell Infect Microbiol2014
24948693Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates.J Infect Dis2014
24444337Evidence of promiscuous endothelial binding by Plasmodium falciparum-infected erythrocytes.Cell Microbiol2014
23297413Molecular architecture of a complex between an adhesion protein from the malaria parasite and intracellular adhesion molecule 1.J Biol Chem2013
23936131Transfected HEK293 cells expressing functional recombinant intercellular adhesion molecule 1 (ICAM-1)--a receptor associated with severe Plasmodium falciparum malaria.PLoS One2013
23741007Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children.Blood2013
23711755A simple protocol for platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes in a resource poor setting.J Vis Exp2013
23209327A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies.J Immunol2013
22324996Cerebral malaria pathogenesis: revisiting parasite and host contributions.Future Microbiol2012
22973133Cytoadherence and severe malaria.Malays J Med Sci2012
23130499The geographical distribution of allele polymorphisms of Plasmodium vivax in different regions of Thailand.J Med Assoc Thai2012
22634746Signal transduction in Plasmodium-Red Blood Cells interactions and in cytoadherence.An Acad Bras Cienc2012
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Collaborators

Chris I Newbold
Wellcome Trust Sanger Institute
Co-authored papers 23
Terrie E Taylor
Kamuzu University of Health Sciences
Co-authored papers 15
Sue Kyes
Weatherall Institute of Molecular Medicine
Co-authored papers 12
Karl B Seydel
Kamuzu University of Health Sciences
Co-authored papers 9
Matthew Berriman
Wellcome Sanger Institute
Co-authored papers 4
Arnab Pain
King Abdullah University of Science and Technology
Co-authored papers 4
Sharen Bowman
NRC Institute for Marine Biosciences
Co-authored papers 4
Bart Barrell
Wellcome Trust Sanger Institute
Co-authored papers 3
Ross L Coppel
Nursing and Health SciencesMonash UniversityClaytonVictoriaAustralia.
Co-authored papers 2
Janet Hemingway
London School of Hygiene & Tropical Medicine
Co-authored papers 2
Neil Hall
Earlham Institute
Co-authored papers 2
Lee Murphy
Edinburgh Clinical Research Facility, University of Edinburgh
Co-authored papers 2
Rhian Gwilliam
The Wellcome Trust Sanger Institute
Co-authored papers 2
Michael G Rossmann
Purdue University
Co-authored papers 2
Kim Rutherford
University of Cambridge
Co-authored papers 2
Taane G Clark
Co-authored papers 2
Keith D James
Wellcome Trust Sanger Institute
Co-authored papers 2
Ian T Paulsen
Macquarie University
Co-authored papers 1
Sirpa Jalkanen
Co-authored papers 1
Man-Suen Chan
University of Oxford
Co-authored papers 1
Alasdair Ivens
University of Washington School of Medicine
Co-authored papers 1
Mark Fleharty
Broad Institute of Harvard and MIT and Harvard
Co-authored papers 1
Michael W Mather
Center for Molecular Parasitology, Drexel University College of Medicine
Co-authored papers 1
Justin P Rubio
Co-authored papers 1
Valentin Ruano-Rubio
Co-authored papers 1
Leda M Cummings
Institute for Genome Research
Co-authored papers 1
Jeremy D Selengut
Craig Venter Institute, 9704 Medical Center Drive
Co-authored papers 1
David M A Martin
University of Dundee
Co-authored papers 1
David S Roos
University of Pennsylvania
Co-authored papers 1
Stuart A Ralph
Bio21 Molecular Science and Biotechnology Institute, University of Melbourne
Co-authored papers 1
Release 1.2