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Author Details

Leonard Moise
EpiVax Inc.
1991
94
29
PMIDPaper TitleJournal TitlePublished Year
36285342H1N1 G4 swine influenza T cell epitope analysis in swine and human vaccines and circulating strains uncovers potential risk to swine and humans.Influenza Other Respir Viruses2023
37705976Identification of immunodominant T cell epitopes induced by natural Zika virus infection.Front Immunol2023
36626370Diversity and evolution of computationally predicted T cell epitopes against human respiratory syncytial virus.PLoS Comput Biol2023
35704783Novel H7N9 influenza immunogen design enhances mobilization of seasonal influenza T cell memory in H3N2 pre-immune mice.Hum Vaccin Immunother2022
35651616Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of <i>Coxiella burnetii</i> Immunity.Front Immunol2022
33278563Self-Replicating RNAs Drive Protective Anti-tumor T Cell Responses to Neoantigen Vaccine Targets in a Combinatorial Approach.Mol Ther2021
34066605Quantifying the Persistence of Vaccine-Related T Cell Epitopes in Circulating Swine Influenza A Strains from 2013-2017.Vaccines (Basel)2021
33986292Highly conserved, non-human-like, and cross-reactive SARS-CoV-2 T cell epitopes for COVID-19 vaccine design and validation.NPJ Vaccines2021
34168657Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification, Characterization, and Downselection of Conserved and Variable Circumsporozoite Protein CD4 T Cell Epitopes From Diverse <i>Plasmodium falciparum</i> Strains.Front Immunol2021
34025684Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From <i>Plasmodium falciparum</i>.Front Immunol2021
34305923Identification and Immune Assessment of T Cell Epitopes in Five <i>Plasmodium falciparum</i> Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization.Front Immunol2021
30614773Immune escape and immune camouflage may reduce the efficacy of RTS,S vaccine in Malawi.Hum Vaccin Immunother2020
33123135New Immunoinformatics Tools for Swine: Designing Epitope-Driven Vaccines, Predicting Vaccine Efficacy, and Making Vaccines on Demand.Front Immunol2020
32908981The immune vulnerability landscape of the 2019 Novel Coronavirus, SARS-CoV-2.bioRxiv2020
32962468Exploit T cell Immunity for Rapid, Safe and Effective COVID-19 Vaccines.Expert Rev Vaccines2020
32783766Immune-engineered H7N9 influenza hemagglutinin improves protection against viral influenza virus challenge.Hum Vaccin Immunother2020
32318055Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools.Front Immunol2020
30828331Promiscuous <i>Coxiella burnetii</i> CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine.Front Immunol2019
31428586Multi-antigen Vaccination With Simultaneous Engagement of the OX40 Receptor Delays Malignant Mesothelioma Growth and Increases Survival in Animal Models.Front Oncol2019
31594990Publisher Correction: A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.Sci Rep2019
31248687A prime-boost concept using a T-cell epitope-driven DNA vaccine followed by a whole virus vaccine effectively protected pigs in the pandemic H1N1 pig challenge model.Vaccine2019
31331958Coxiella burnetii Epitope-Specific T-Cell Responses in Patients with Chronic Q Fever.Infect Immun2019
31331771Highly conserved influenza T cell epitopes induce broadly protective immunity.Vaccine2019
30015562T cell epitope engineering: an avian H7N9 influenza vaccine strategy for pandemic preparedness and response.Hum Vaccin Immunother2018
28575582An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice.Hum Vaccin Immunother2017
28455520A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.Sci Rep2017
29054116T-cell epitope content comparison (EpiCC) of swine H1 influenza A virus hemagglutinin.Influenza Other Respir Viruses2017
27411061In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model.PLoS One2016
26588466T cell epitope redundancy: cross-conservation of the TCR face between pathogens and self and its implications for vaccines and autoimmunity.Expert Rev Vaccines2016
28010520Innovation, urgency and acceptance at the 9th Vaccine Renaissance.Hum Vaccin Immunother2016
27389971Agility in adversity: Vaccines on Demand.Expert Rev Vaccines2016
25385064C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cells.Immunol Cell Biol2015
26370412Development and validation of an epitope prediction tool for swine (PigMatrix) based on the pocket profile method.BMC Bioinformatics2015
26107442An immunoinformatic approach for identification of Trypanosoma cruzi HLA-A2-restricted CD8(+) T cell epitopes.Hum Vaccin Immunother2015
261582258th vaccine renaissance: A creative nexus for vaccine developers.Hum Vaccin Immunother2015
26155959iVAX: An integrated toolkit for the selection and optimization of antigens and the design of epitope-driven vaccines.Hum Vaccin Immunother2015
26042612Preclinical development of HIvax: Human survivin highly immunogenic vaccines.Hum Vaccin Immunother2015
26151066Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance.Mol Ther Methods Clin Dev2015
26090577H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance.Hum Vaccin Immunother2015
25193104Time for T? Immunoinformatics addresses vaccine design for neglected tropical and emerging infectious diseases.Expert Rev Vaccines2015
24686319A high throughput MHC II binding assay for quantitative analysis of peptide epitopes.J Vis Exp2014
25483703Immune camouflage: relevance to vaccines and human immunology.Hum Vaccin Immunother2014
25483693VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever.Hum Vaccin Immunother2014
25517089Partial pathogen protection by tick-bite sensitization and epitope recognition in peptide-immunized HLA DR3 transgenic mice.Hum Vaccin Immunother2014
25339942Smarter vaccine design will circumvent regulatory T cell-mediated evasion in chronic HIV and HCV infection.Front Microbiol2014
25104221Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage.BMC Bioinformatics2014
24740005Human immune responses to H. pylori HLA Class II epitopes identified by immunoinformatic methods.PLoS One2014
24888712CHOPPI: a web tool for the analysis of immunogenicity risk from host cell proteins in CHO-based protein production.Biotechnol Bioeng2014
24525618Cross-conservation of T-cell epitopes: now even more relevant to (H7N9) influenza vaccine design.Hum Vaccin Immunother2014
22941509In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity.J Clin Immunol2013
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Collaborators

University of Georgia
Co-authored papers 84
EpiVax Inc.
Co-authored papers 55
Center for Vaccines and Immunology, University of Georgia
Co-authored papers 10
University of Colorado - Anschutz Medical Campus
Co-authored papers 8
Brown University, Rhode Island Providence VA Medical Center
Co-authored papers 6
University of Massachusetts Medical School
Co-authored papers 4
Rhode Island Hospital and the Warren Alpert Medical School of Brown University
Co-authored papers 4
University of Copenhagen
Co-authored papers 3
University of British Columbia
Co-authored papers 3
Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea
Co-authored papers 2
Saint Louis University School of Medicine
Co-authored papers 2
Institute for Social Science Research, The University of Queensland
Co-authored papers 2
Center for Natural Products Research, University of Havana
Co-authored papers 2
University of Science
Co-authored papers 2
The University of Texas Southwestern Medical Center
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
McLean Hospital and Program in Neuroscience, Harvard Medical School
Co-authored papers 1
Universite Libre de Bruxelles
Co-authored papers 1
France French Academy of Pharmacy
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
Warren Alpert School of Medicine at Brown University
Co-authored papers 1
Massachusetts General Hospital
Co-authored papers 1
Wistar Institute
Co-authored papers 1
Brown University, Rhode Island Hospital
Co-authored papers 1
Co-authored papers 1
Faculty of Medicine and Odonto-Stomatology (FMOS)/University of Sciences
Co-authored papers 1
University of Massachusetts Chan Medical School
Co-authored papers 1
Quantitative Biomedical Research Center
Co-authored papers 1
University of California los angeles
Co-authored papers 1