Skip to Main Content

Author Details

Paul J R Barton
1985
163
57
PMIDPaper TitleJournal TitlePublished Year
37431535Ethnicity, consanguinity, and genetic architecture of hypertrophic cardiomyopathy.2023
37652022The penetrance of rare variants in cardiomyopathy-associated genes: A cross-sectional approach to estimating penetrance for secondary findings.Am J Hum Genet2023
37629170Cardiomyocyte-Restricted Expression of IL11 Causes Cardiac Fibrosis, Inflammation, and Dysfunction.2023
34380661Moderate excess alcohol consumption and adverse cardiac remodelling in dilated cardiomyopathy.Heart2022
35654493Precision Phenotyping of Dilated Cardiomyopathy Using Multidimensional Data.J Am Coll Cardiol2022
36154167Genetic Architecture of Acute Myocarditis and the Overlap With Inherited Cardiomyopathy.Circulation2022
35926050Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies.Science2022
34503678Phenotypic Expression and Outcomes in Individuals With Rare Genetic Variants of Hypertrophic Cardiomyopathy.Journal of the American College of Cardiology2021
33500567Systematic large-scale assessment of the genetic architecture of left ventricular noncompaction reveals diverse etiologies.Genet Med2021
34022131Non-coding region variants upstream of MEF2C cause severe developmental disorder through three distinct loss-of-function mechanisms.Am J Hum Genet2021
33495596Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect.Nat Genet2021
33046849Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions.Genet Med2021
34461741Contribution of Noncanonical Splice Variants to <i>TTN</i> Truncating Variant Cardiomyopathy.Circ Genom Precis Med2021
34460321New Variant With a Previously Unrecognized Mechanism of Pathogenicity in Hypertrophic Cardiomyopathy.Circulation2021
33110626The Egyptian Collaborative Cardiac Genomics (ECCO-GEN) Project: defining a healthy volunteer cohort.npj Genomic Medicine2020
32306808Contemporary Insights Into the Genetics of Hypertrophic Cardiomyopathy: Toward a New Era in Clinical Testing?Journal of the American Heart Association2020
32815737Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in <i>TNNI3</i> and <i>TNNT2</i> That Are Common in Chinese Patients.Circ Genom Precis Med2020
30987448Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy.Circulation2019
29892087A gene-centric strategy for identifying disease-causing rare variants in dilated cardiomyopathy.Genet Med2019
30609406Using High-Resolution Variant Frequencies Empowers Clinical Genome Interpretation and Enables Investigation of Genetic Architecture.Am J Hum Genet2019
31284728Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins.Circulation2019
30696458Quantitative approaches to variant classification increase the yield and precision of genetic testing in Mendelian diseases: the case of hypertrophic cardiomyopathy.Genome Med2019
31501434Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.Nat Commun2019
31399586WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.Nat Commun2019
31251381Association of Titin-Truncating Genetic Variants With Life-threatening Cardiac Arrhythmias in Patients With Dilated Cardiomyopathy and Implanted Defibrillators.JAMA network open2019
31155234The Translational Landscape of the Human Heart.Cell2019
29773157Genetic Etiology for Alcohol-Induced Cardiac Toxicity.Journal of the American College of Cardiology2018
30442290Dilated Cardiomyopathy Due to BLC2-Associated Athanogene 3 (BAG3) Mutations.Journal of the American College of Cardiology2018
29369293CardioClassifier: disease- and gene-specific computational decision support for clinical genome interpretation.Genetics in Medicine2018
28082330Defining the genetic architecture of hypertrophic cardiomyopathy: re-evaluating the role of non-sarcomeric genes.Eur Heart J2017
28903782Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy.Genome Biol2017
28494986Truncating Variants in Titin Independently Predict Early Arrhythmias in Patients With Dilated Cardiomyopathy.Journal of the American College of Cardiology2017
28518168Using high-resolution variant frequencies to empower clinical genome interpretation.Genet Med2017
29073955Phenotype and Clinical Outcomes of Titin Cardiomyopathy.J Am Coll Cardiol2017
28050600Histiocytoid cardiomyopathy and microphthalmia with linear skin defects syndrome: phenotypes linked by truncating variants in <i>NDUFB11</i>.Cold Spring Harb Mol Case Stud2017
27869827Titin-truncating variants affect heart function in disease cohorts and the general population.Nat Genet2017
27746127The Calcineurin Variant CnAβ1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation.Cell Chem Biol2016
27437901Recovery of Cardiac Function in Cardiomyopathy Caused by Titin Truncation.JAMA Cardiology2016
26888179Development of a Comprehensive Sequencing Assay for Inherited Cardiac Condition Genes.Journal of Cardiovascular Translational Research2016
26535225Genetic modifiers to the PLN L39X mutation in a patient with DCM and sustained ventricular tachycardia?Glob Cardiol Sci Pract2015
25589632Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.Sci Transl Med2015
25889438Involvement of BAG3 and HSPB7 loci in various etiologies of systolic heart failure: Results of a European collaboration assembling more than 2000 patients.Int J Cardiol2015
26175529ZBTB17 (MIZ1) Is Important for the Cardiac Stress Response and a Novel Candidate Gene for Cardiomyopathy and Heart Failure.Circ Cardiovasc Genet2015
26078397Influence of glutathione-S-transferase (GST) inhibition on lung epithelial cell injury: role of oxidative stress and metabolism.American Journal of Physiology - Lung Cellular and Molecular Physiology2015
26453460Review and Updates in Regenerative and Personalized Medicine, Preclinical Animal Models, and Clinical Care in Cardiovascular Medicine.J Cardiovasc Transl Res2015
24960161RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.J Clin Invest2014
25516437Regulated inositol-requiring protein 1-dependent decay as a mechanism of corin RNA and protein deficiency in advanced human systolic heart failure.Journal of the American Heart Association2014
24431031AMP deaminase 1 gene polymorphism and heart disease-a genetic association that highlights new treatment.Cardiovascular Drugs and Therapy2014
25033200Identification of a new target of miR-16, Vacuolar Protein Sorting 4a.PLoS One2014
24940686Effect of AMP-deaminase 3 knock-out in mice on enzyme activity in heart and other organs.Nucleosides, Nucleotides and Nucleic Acids2014
  • 1 - 50 of 163

Recommended Authors

Collaborators

Co-authored papers 65
Co-authored papers 43
Co-authored papers 41
Co-authored papers 32
Co-authored papers 26
Co-authored papers 25
Co-authored papers 24
Co-authored papers 18
Co-authored papers 13
Co-authored papers 13
Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 12
Co-authored papers 11
Institute for Precision Cardiovascular Medicine
Co-authored papers 11
Co-authored papers 11
Co-authored papers 10
Co-authored papers 9
Harvard Medical School
Co-authored papers 9
National Heart and Lung Institute, Imperial College London
Co-authored papers 9
Brigham and Women's Hospital (Y.K.
Co-authored papers 9
Co-authored papers 8
Partners Healthcare Center for Personalized Genetic Medicine
Co-authored papers 5
Co-authored papers 5
Co-authored papers 5
University of Cambridge
Co-authored papers 5
British Heart Foundation Centre of Research Excellence, University of Glasgow
Co-authored papers 4
Duke-National University of Singapore
Co-authored papers 4
Co-authored papers 4
Co-authored papers 4
Stanford University
Co-authored papers 3
Co-authored papers 3