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Author Details

Timothy C Cox
University of Missouri-Kansas City Kansas City
1990
140
40
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36245435Altering osteoclast numbers using CTSK models in utero affects mice offspring craniofacial morphology.Orthod Craniofac Res2023
37635302Hypomyelination, hypodontia and craniofacial abnormalities in a Polr3b mouse model of leukodystrophy.Brain2023
37183792Transcriptomic analysis reveals the role of SIX1 in mouse cranial neural crest patterning and bone development.Dev Dyn2023
37341808The spontaneous mouse mutant low set ears (Lse) is caused by tandem duplication of Fgf3 and Fgf4.Mamm Genome2023
37041148FOXI3 pathogenic variants cause one form of craniofacial microsomia.Nat Commun2023
37277650Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model.Nat Genet2023
36751037A mutational hotspot in AMOTL1 defines a new syndrome of orofacial clefting, cardiac anomalies, and tall stature.Am J Med Genet A2023
36833249A Founder Intronic Variant in <i>P3H1</i> Likely Results in Aberrant Splicing and Protein Truncation in Patients of Karen Descent with Osteogenesis Imperfecta Type VIII.Genes (Basel)2023
36833193<i>SERPINB3</i>, Adult-Onset Immunodeficiency, and Generalized Pustular Psoriasis.Genes (Basel)2023
36829498Rare Variants in <i>LRP4</i> Are Associated with Mesiodens, Root Maldevelopment, and Oral Exostoses in Humans.Biology (Basel)2023
36901686Rare Genetic Variants in Human <i>APC</i> Are Implicated in Mesiodens and Isolated Supernumerary Teeth.Int J Mol Sci2023
35266954The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity.J Cell Biol2022
36476934NAD precursors cycle between host tissues and the gut microbiome.Cell Metab2022
36672844Loss of Function <i>TGFBR2</i> Variant as a Contributing Factor in Generalized Pustular Psoriasis and Adult-Onset Immunodeficiency.Genes (Basel)2022
35909127TRIM18 is a critical regulator of viral myocarditis and organ inflammation.J Biomed Sci2022
35131118Altering calcium and phosphorus supplementation in pregnancy and lactation affects offspring craniofacial morphology in a sex-specific pattern.Am J Orthod Dentofacial Orthop2022
35284927Auriculocondylar syndrome 2 results from the dominant-negative action of PLCB4 variants.Dis Model Mech2022
33417889A dyadic approach to the delineation of diagnostic entities in clinical genomics.Am J Hum Genet2021
33547071A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation.Sci Adv2021
33811546Pathogenic variants in CDH11 impair cell adhesion and cause Teebi hypertelorism syndrome.Hum Genet2021
34383890GATA3 is essential for separating patterning domains during facial morphogenesis.Development2021
33473216Survey of spiking in the mouse visual system reveals functional hierarchy.Nature2021
32342860Rapamycin rejuvenates oral health in aging mice.Elife2020
31945113Sonic Hedgehog upregulation does not enhance the survival and engraftment of stem cell-derived cardiomyocytes in infarcted hearts.PLoS One2020
32784565A Synonymous Exonic Splice Silencer Variant in IRF6 as a Novel and Cryptic Cause of Non-Syndromic Cleft Lip and Palate.Genes (Basel)2020
32754047Effects of Multi-Generational Soft Diet Consumption on Mouse Craniofacial Morphology.Front Physiol2020
32407962Microcomputed tomography of craniofacial mineralized tissue: A practical user's guide to study planning and generating quality data.Bone2020
32352199The Society for Craniofacial Genetics and Developmental Biology 42nd Annual Meeting.Am J Med Genet A2020
32260281<i>CDH1</i> Mutation Distribution and Type Suggests Genetic Differences between the Etiology of Orofacial Clefting and Gastric Cancer.Genes (Basel)2020
30793834The Society for Craniofacial Genetics and Developmental Biology 41st Annual Meeting.Am J Med Genet A2019
31215115Mutations in GDF11 and the extracellular antagonist, Follistatin, as a likely cause of Mendelian forms of orofacial clefting in humans.Hum Mutat2019
31074150Altering calcium and phosphorus levels in utero affects adult mouse mandibular morphology.Orthod Craniofac Res2019
30814516Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.Nat Commun2019
29215649A craniosynostosis massively parallel sequencing panel study in 309 Australian and New Zealand patients: findings and recommendations.Genet Med2018
29805042Mutations in the Epithelial Cadherin-p120-Catenin Complex Cause Mendelian Non-Syndromic Cleft Lip with or without Cleft Palate.Am J Hum Genet2018
30041812PiT-2, a type III sodium-dependent phosphate transporter, protects against vascular calcification in mice with chronic kidney disease fed a high-phosphate diet.Kidney Int2018
29575621Associations between laterality of orofacial clefts and medical and academic outcomes.Am J Med Genet A2018
29681098The Society for Craniofacial Genetics and Developmental Biology 40th annual meeting.Am J Med Genet A2018
29133259Loss of PiT-2 results in abnormal bone development and decreased bone mineral density and length in mice.Biochem Biophys Res Commun2018
29232056Associations between laterality of orofacial clefts and medical and academic outcomes.Am J Med Genet A2018
26822507SLC20A2 Deficiency in Mice Leads to Elevated Phosphate Levels in Cerbrospinal Fluid and Glymphatic Pathway-Associated Arteriolar Calcification, and Recapitulates Human Idiopathic Basal Ganglia Calcification.Brain Pathol2017
28360863Differences in Oral Structure and Tissue Interactions during Mouse vs. Human Palatogenesis: Implications for the Translation of Findings from Mice.Front Physiol2017
28194360Retreatability of two endodontic sealers, EndoSequence BC Sealer and AH Plus: a micro-computed tomographic comparison.Restor Dent Endod2017
28455376Negative regulation of endothelin signaling by SIX1 is required for proper maxillary development.Development2017
29198719Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment.Am J Hum Genet2017
28650075Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor.J Bone Miner Res2017
28691340Intra- and Intersexual swim bladder dimorphisms in the plainfin midshipman fish (Porichthys notatus): Implications of swim bladder proximity to the inner ear for sound pressure detection.J Morphol2017
28767310Disrupted IRF6-NME1/2 Complexes as a Cause of Cleft Lip/Palate.J Dent Res2017
28889220Rapamycin treatment attenuates age-associated periodontitis in mice.Geroscience2017
27927890Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model.J Dent Res2017
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Collaborators

Prince of Wales Hospital
Co-authored papers 13
Department of Biological Structure University of Washington
Co-authored papers 5
Columbia University.
Co-authored papers 4
University of Washington
Co-authored papers 4
University of Washington
Co-authored papers 3
Co-authored papers 3
Center for Craniofacial and Dental Genetics, University of Pittsburgh
Co-authored papers 3
University of Washington
Co-authored papers 3
Co-authored papers 2
University of Pittsburgh
Co-authored papers 2
Co-authored papers 2
Clinical Geneticist, Genetic Health Service
Co-authored papers 2
KTH - Royal Institute of Technology
Co-authored papers 2
Cincinnati Children's Hospital Medical Center
Co-authored papers 2
Co-authored papers 2
University of Washington School of Medicine
Co-authored papers 2
King Edward Memorial Hospital
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
UCSF Helen Diller Family Comprehensive Cancer Center
Co-authored papers 2
Department of Medical Genomics/Clinical Genetics, Royal Prince Alfred Hospital
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University of Melbourne, The Royal Children's Hospital
Co-authored papers 2
Co-authored papers 2
Children's Hospital of Philadelphia
Co-authored papers 2
Co-authored papers 2
Brotman Baty Institute for Precision Medicine, University of Washington
Co-authored papers 2