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Author Details

Timothy R Billiar
University of Pittsburgh
1984
813
130
PMIDPaper TitleJournal TitlePublished Year
38095316Transcriptomic and Proteomic Characterization of the Immune Response to Elective Spinal Reconstructive Surgery: Impact of Aging and Comparison with Traumatic Injury Response.J Am Coll Surg2024
37916404Transforming the Future of Surgeon-Scientists.Ann Surg2024
35129530Low Titer Group O Whole Blood In Injured Children Requiring Massive Transfusion.Ann Surg2023
38016467Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis.Immunity2023
37652366Nitric oxide and thioredoxin modulate the activity of caspase 9 in HepG2 cells.Biochim Biophys Acta Gen Subj2023
38034362A common single nucleotide polymorphism is associated with inflammation and critical illness outcomes.iScience2023
37421629ADAR1 Zα domain P195A mutation activates the MDA5-dependent RNA-sensing signaling pathway in brain without decreasing overall RNA editing.Cell Rep2023
37466669Targeting inflammation in traumatic injury: entering a new era.Intensive Care Med2023
37169743Interferon-gamma is quintessential for NOS2 and COX2 expression in ER<sup>-</sup> breast tumors that lead to poor outcome.Cell Death Dis2023
37066331Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER <sup>-</sup> Breast Tumors that Lead to Poor Outcome.bioRxiv2023
37095162Central role for neurally dysregulated IL-17A in dynamic networks of systemic and local inflammation in combat casualties.Sci Rep2023
36520504Targeting Nitric Oxide: Say NO to Metastasis.Clin Cancer Res2023
36787435High-dimensional proteomics identifies organ injury patterns associated with outcomes in human trauma.J Trauma Acute Care Surg2023
36735480Direct Trauma Center Access by Helicopter Emergency Medical Services is Associated With Improved Survival After Severe Injury.Ann Surg2023
34742907Analysis of glutathione mediated S-(de)nitrosylation in complex biological matrices by immuno-spin trapping and identification of two novel substrates.Nitric Oxide2022
35511979Z-DNA binding protein 1 promotes heatstroke-induced cell death.Science2022
35800765Impaired interferon-γ signaling promotes the development of silicosis.iScience2022
35438146Robust and accurate estimation of cellular fraction from tissue omics data via ensemble deconvolution.Bioinformatics2022
35832091Single-cell transcriptome profiling of the immune space-time landscape reveals dendritic cell regulatory program in polymicrobial sepsis.Theranostics2022
35663944Inferring Tissue-Specific, TLR4-Dependent Type 17 Immune Interactions in Experimental Trauma/Hemorrhagic Shock and Resuscitation Using Computational Modeling.Front Immunol2022
35861072High Dimensional Multiomics Reveals Unique Characteristics of Early Plasma Administration in Polytrauma Patients With TBI.Ann Surg2022
36567402Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression.Mil Med Res2022
36532045Plasma proteomics reveals early, broad release of chemokine, cytokine, TNF, and interferon mediators following trauma with delayed increases in a subset of chemokines and cytokines in patients that remain critically ill.Front Immunol2022
36001682Aconitate decarboxylase 1 is a mediator of polymicrobial sepsis.Sci Transl Med2022
36278484Intraperitoneal injection of class A TLR9 agonist enhances anti-PD-1 immunotherapy in colorectal peritoneal metastases.JCI Insight2022
36144179Multi-Omic Admission-Based Prognostic Biomarkers Identified by Machine Learning Algorithms Predict Patient Recovery and 30-Day Survival in Trauma Patients.Metabolites2022
35904142LONGITUDINAL ANALYSIS OF TRANSCRIPTOMIC SUBTYPES IN TRAUMA PATIENTS.Shock2022
36357394Lipidomic signatures align with inflammatory patterns and outcomes in critical illness.Nat Commun2022
36112847Short-Term Administration of HIV Protease Inhibitor Saquinavir Improves Skull Bone Healing with Enhanced Osteoclastogenesis.Plast Reconstr Surg2022
34890842Hepatocytes Are Resistant to Cell Death From Canonical and Non-Canonical Inflammasome-Activated Pyroptosis.Cell Mol Gastroenterol Hepatol2022
35124428The independent prognostic value of global epigenetic alterations: An analysis of single-cell ATAC-seq of circulating leukocytes from trauma patients followed by validation in whole blood leukocyte transcriptomes across three etiologies of critical illness.EBioMedicine2022
35272622GRK2 regulates group 2 innate lymphoid cell mobilization in sepsis.Mol Med2022
35081595Prehospital low titer group O whole blood is feasible and safe: Results of a prospective randomized pilot trial.J Trauma Acute Care Surg2022
34924514Patient-Specific Precision Injury Signatures to Optimize Orthopaedic Interventions in Multiply Injured Patients (PRECISE STUDY).J Orthop Trauma2022
30998533Prehospital Blood Product and Crystalloid Resuscitation in the Severely Injured Patient: A Secondary Analysis of the Prehospital Air Medical Plasma Trial.Ann Surg2021
33854044A small molecule binding HMGB1 inhibits caspase-11-mediated lethality in sepsis.Cell Death Dis2021
33493891The Whole is Greater Than the Sum of its Parts: GCS Versus GCS-Motor for Triage in Geriatric Trauma.J Surg Res2021
33906793Emerging mechanisms of immunocoagulation in sepsis and septic shock.Trends Immunol2021
33710107Single-Cell Transcriptomics Reveals Compartment-Specific Differences in Immune Responses and Contributions for Complement Factor 3 in Hemorrhagic Shock Plus Tissue Trauma.Shock2021
33537029Computational Derivation of Core, Dynamic Human Blunt Trauma Inflammatory Endotypes.Front Immunol2021
33561388Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties.Immunity2021
33860683The Use of Multiplexing to Identify Cytokine and Chemokine Networks in the Immune-Inflammatory Response to Trauma.Antioxid Redox Signal2021
33748428Protective/reparative cytokines are suppressed at high injury severity in human trauma.Trauma Surg Acute Care Open2021
33632134Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway.Mol Med2021
33687949Platelet TLR4-ERK5 Axis Facilitates NET-Mediated Capturing of Circulating Tumor Cells and Distant Metastasis after Surgical Stress.Cancer Res2021
33605701Geospatial assessment of helicopter emergency medical service overtriage.J Trauma Acute Care Surg2021
35028617Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses.Cell Rep Med2021
34969816ADAR1 RNA editing regulates endothelial cell functions via the MDA-5 RNA sensing signaling pathway.Life Sci Alliance2021
34385304HMGB1 released from nociceptors mediates inflammation.Proc Natl Acad Sci U S A2021
34570435Immuno-Spin Trapping Method for the Analysis of S-Nitrosylated Proteins.Curr Protoc2021
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Collaborators

Yoram Vodovotz
University of Pittsburgh
Co-authored papers 120
Andrew B Peitzman
University of Pittsburgh Medical Center
Co-authored papers 97
Jason L Sperry
University of Pittsburgh Medical Center
Co-authored papers 92
Ruben Zamora
University of Pittsburgh
Co-authored papers 48
Matthew R Rosengart
University of Pittsburgh
Co-authored papers 39
Simon C Watkins
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers 39
Matthew D Neal
University of Pittsburgh Medical Center
Co-authored papers 38
Derek Barclay
University of Pittsburgh
Co-authored papers 21
Ronald V Maier
University of Washington
Co-authored papers 17
Juan B Ochoa
Hunterdon Medical Center
Co-authored papers 16
Ryan M Levy
University of Pittsburgh Medical Center
Co-authored papers 16
Francis X Guyette
Co-authored papers 16
Mitchell P Fink
University of Pittsburgh School of Medicine
Co-authored papers 16
Jose M Prince
Cincinnati Children's Hospital Medical Center
Co-authored papers 16
Rajaie Namas
Medical Subspecialities Institute, Cleveland Clinic
Co-authored papers 14
Joseph Cuschieri
Harborview Medical Center
Co-authored papers 14
Qi Mi
University of Pittsburgh
Co-authored papers 13
Gregory Constantine
University of Pittsburgh
Co-authored papers 8
Christine M Leeper
University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh
Co-authored papers 8
Lyle L Moldawer
University of Florida College of Medicine.
Co-authored papers 8
Frank B Cerra
IRCCS Centro Neurolesi Messina
Co-authored papers 8
David Gallo
Beth Israel Deaconess Medical Center, Harvard Medical School
Co-authored papers 7
Derek C Angus
University of Pittsburgh Medical Center
Co-authored papers 7
Barbara A Gaines
University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh
Co-authored papers 7
Constantino M Lagoa
The Pennsylvania State University, University Park
Co-authored papers 6
Ronald G Tompkins
Massachusetts General Hospital
Co-authored papers 6
Patrick M Kochanek
University of Pittsburgh School of Medicine
Co-authored papers 6
Juan Carlos Puyana
and Clinical Translational Science, University of Pittsburgh
Co-authored papers 6
Hilary S Warren
Massachusetts General Hospital
Co-authored papers 5
Michael N Mindrinos
Stanford University
Co-authored papers 5
Release 1.2