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Author Details
Full Name
Lars Pache
Affiliation
Sanford Burnham Prebys Medical Discovery Institute
ORCID
Career Start Year
2003
Papers
39
H Index
21
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36823157
Developing a standardized but extendable framework to increase the findability of infectious disease datasets.
Sci Data
2023
37758692
Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets.
Nat Commun
2023
38077015
Host immune responses associated with SARS-CoV-2 Omicron infection result in protection or pathology during reinfection depending on mouse genetic background.
Res Sq
2023
37425792
Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian Hamsters.
bioRxiv
2023
36823198
Addressing barriers in FAIR data practices for biomedical data.
Sci Data
2023
36197970
Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans.
Sci Adv
2022
35766385
Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity.
ACS Infect Dis
2022
34843601
A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.
PLoS Pathog
2021
33727703
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2.
Nature
2021
33930332
Functional landscape of SARS-CoV-2 cellular restriction.
Mol Cell
2021
34556855
Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy.
Nat Microbiol
2021
32511357
A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals.
bioRxiv
2020
33052331
Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters.
Res Sq
2020
33024967
Functional Landscape of SARS-CoV-2 Cellular Restriction.
bioRxiv
2020
33205060
Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo.
Cell Rep Med
2020
32882949
The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription.
Cells
2020
32707573
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.
Nature
2020
30717826
HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses.
Elife
2019
30944313
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.
Nat Commun
2019
29760472
Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.
Sci Rep
2018
30146161
Transcription Elongation Can Affect Genome 3D Structure.
Cell
2018
29391557
SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.
Sci Rep
2018
29490283
Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu.
Cell Rep
2018
28475896
The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity.
Cell
2017
26651948
Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.
Cell Host Microbe
2015
26355217
BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.
Cell Host Microbe
2015
24817247
An integrated map of HIV-human protein complexes that facilitate viral infection.
PLoS One
2014
24760882
Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner.
J Virol
2014
22860749
Functional genomic and high-content screening for target discovery and deconvolution.
Expert Opin Drug Discov
2012
20654720
Identifying HIV-1 host cell factors by genome-scale RNAi screening.
Methods
2011
22190034
Global landscape of HIV-human protein complexes.
Nature
2011
21777475
GPS-Prot: a web-based visualization platform for integrating host-pathogen interaction data.
BMC Bioinformatics
2011
20027183
Human host factors required for influenza virus replication.
Nature
2010
19019405
Insights into adenovirus host cell interactions from structural studies.
Virology
2009
18336857
Conservation of fiber structure and CD46 usage by subgroup B2 adenoviruses.
Virology
2008
18524830
Structural variations in species B adenovirus fibers impact CD46 association.
J Virol
2008
17180119
Enhancement of gene transfer to human myeloid cells by adenovirus-fiber complexes.
Mol Ther
2007
15047806
Membrane cofactor protein is a receptor for adenoviruses associated with epidemic keratoconjunctivitis.
J Virol
2004
12805421
Flexibility of the adenovirus fiber is required for efficient receptor interaction.
J Virol
2003
1 - 39 of 39
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