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Author Details

Lars Pache
Sanford Burnham Prebys Medical Discovery Institute
2003
39
21
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36823157Developing a standardized but extendable framework to increase the findability of infectious disease datasets.Sci Data2023
37758692Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets.Nat Commun2023
38077015Host immune responses associated with SARS-CoV-2 Omicron infection result in protection or pathology during reinfection depending on mouse genetic background.Res Sq2023
37425792Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian Hamsters.bioRxiv2023
36823198Addressing barriers in FAIR data practices for biomedical data.Sci Data2023
36197970Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans.Sci Adv2022
35766385Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity.ACS Infect Dis2022
34843601A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.PLoS Pathog2021
33727703Clofazimine broadly inhibits coronaviruses including SARS-CoV-2.Nature2021
33930332Functional landscape of SARS-CoV-2 cellular restriction.Mol Cell2021
34556855Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy.Nat Microbiol2021
32511357A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals.bioRxiv2020
33052331Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters.Res Sq2020
33024967Functional Landscape of SARS-CoV-2 Cellular Restriction.bioRxiv2020
33205060Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo.Cell Rep Med2020
32882949The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription.Cells2020
32707573Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.Nature2020
30717826HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses.Elife2019
30944313Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.Nat Commun2019
29760472Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.Sci Rep2018
30146161Transcription Elongation Can Affect Genome 3D Structure.Cell2018
29391557SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.Sci Rep2018
29490283Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu.Cell Rep2018
28475896The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity.Cell2017
26651948Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.Cell Host Microbe2015
26355217BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.Cell Host Microbe2015
24817247An integrated map of HIV-human protein complexes that facilitate viral infection.PLoS One2014
24760882Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner.J Virol2014
22860749Functional genomic and high-content screening for target discovery and deconvolution.Expert Opin Drug Discov2012
20654720Identifying HIV-1 host cell factors by genome-scale RNAi screening.Methods2011
22190034Global landscape of HIV-human protein complexes.Nature2011
21777475GPS-Prot: a web-based visualization platform for integrating host-pathogen interaction data.BMC Bioinformatics2011
20027183Human host factors required for influenza virus replication.Nature2010
19019405Insights into adenovirus host cell interactions from structural studies.Virology2009
18336857Conservation of fiber structure and CD46 usage by subgroup B2 adenoviruses.Virology2008
18524830Structural variations in species B adenovirus fibers impact CD46 association.J Virol2008
17180119Enhancement of gene transfer to human myeloid cells by adenovirus-fiber complexes.Mol Ther2007
15047806Membrane cofactor protein is a receptor for adenoviruses associated with epidemic keratoconjunctivitis.J Virol2004
12805421Flexibility of the adenovirus fiber is required for efficient receptor interaction.J Virol2003
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Collaborators

The Scripps Research Institute
Co-authored papers 26
Icahn School of Medicine at Mount Sinai
Co-authored papers 13
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 11
University of California San Francisco
Co-authored papers 9
Icahn School of Medicine at Mount Sinai
Co-authored papers 9
The Scripps Research Institute
Co-authored papers 8
Michigan State University College of Human Medicine
Co-authored papers 8
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 7
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Co-authored papers 7
University of California San Diego
Co-authored papers 7
Northwestern University Feinberg School of Medicine
Co-authored papers 7
Icahn School of Medicine at Mount Sinai
Co-authored papers 6
Roche Pharma
Co-authored papers 6
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 6
Paul-Ehrlich-Institut
Co-authored papers 5
University of California San Diego
Co-authored papers 5
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 5
Salk Institute for Biological Studies
Co-authored papers 4
University Hospital of Wurzburg
Co-authored papers 4
University of California los angeles
Co-authored papers 4
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
The Scripps Research Institute
Co-authored papers 4
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 4
Gladstone Institutes
Co-authored papers 4
Institute of Medical Virology, University of Zurich
Co-authored papers 3
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Co-authored papers 3
UC San Diego
Co-authored papers 3
Carlson College of Veterinary Medicine, Oregon State University
Co-authored papers 3
College of Veterinary Medicine, Oregon State University
Co-authored papers 3