Author details

Full Name

Kai Xu

Affiliation

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37098956	Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.		2023
36093594	A plant virus hijacks phosphatidylinositol-3,5-bisphosphate to escape autophagic degradation in its insect vector.		2023
37989731	Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.		2023
37886518	Human CD4-Binding Site Antibody Elicited by Polyvalent DNA Prime-Protein Boost Vaccine Neutralizes Cross-Clade Tier-2-HIV Strains.		2023
37446014	Development and Characterization of Near-Isogenic Lines Derived from Synthetic Wheat Revealing the 2 kb Insertion in the Gene Responsible for Heading Delay and Grain Number Improvement.		2023
35067298	Brassica evolution of essential BnaFtsH1 genes involved in the PSII repair cycle and loss of FtsH5.	Plant Science	2022
36240764	Evasion of neutralizing antibody responses by the SARS-CoV-2 BA.2.75 variant.		2022
36299433	Determinants and Mechanisms of the Low Fusogenicity and Endosomal Entry of Omicron Subvariants.	bioRxiv	2022
36032970	Evasion of Neutralizing Antibody Response by the SARS-CoV-2 BA.2.75 Variant.		2022
36290371	The Characterization of the Tobacco-Derived Wild Tomato Mosaic Virus by Employing Its Infectious DNA Clone.	Biology	2022
35958157	Phosphorylation of plant virus proteins: Analysis methods and biological functions.	Frontiers in Microbiology	2022
35617431	Potent monoclonal antibody-mediated neutralization of a divergent Hendra virus variant.	Proceedings of the National Academy of Sciences of the United States of America	2022
34768098	Inhibitory monoclonal antibody targeting ADAM17 expressed on cancer cells.	Translational Oncology	2022
34638814	The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism.	International Journal of Molecular Sciences	2021
33809833	Functional Analysis of the Fusion and Attachment Glycoproteins of Mojiang Henipavirus.	Viruses	2021
33688659	Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants.	bioRxiv	2021
33576790	The serine/threonine/tyrosine kinase STY46 defends against hordeivirus infection by phosphorylating Î³b protein.	Plant Physiology	2021
33669866	Fine Mapping and Identification of , a Lethal Gene That Regulates the PSII Repair Cycle in .	International Journal of Molecular Sciences	2021
34098567	Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.	Nature	2021
33826898	Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base.	Cell Reports	2021
34303025	A cell wall-localized NLR confers resistance to Soybean mosaic virus by recognizing viral-encoded cylindrical inclusion protein.	Molecular Plant	2021
34244481	Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.	Nature Communications	2021
33649208	Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.	Proc Natl Acad Sci U S A	2021
34981053	Neutralization and Stability of SARS-CoV-2 Omicron Variant.		2021
34788599	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.	Immunity	2021
33333740	Virus-Like Particle Based Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide.	Vaccines	2020
32269127	Co-opted Cellular Sac1 Lipid Phosphatase and PI(4)P Phosphoinositide Are Key Host Factors during the Biogenesis of the Tombusvirus Replication Compartment.	Journal of Virology	2020
32130953	VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.	Cell Host Microbe	2020
32295908	Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.	Journal of Virology	2020
32657215	Characterization of GFP-AtPEN1 as a marker protein for extracellular vesicles isolated from leaves.		2020
32755575	Immune Monitoring Reveals Fusion Peptide Priming to Imprint Cross-Clade HIV-Neutralizing Responses with a Characteristic Early B Cell Signature.	Cell Rep	2020
33028214	Genome-wide characterization, evolution and expression profiling of UDP-glycosyltransferase family in pomelo (Citrus grandis) fruit.	BMC Plant Biology	2020
30995238	Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting.	PLoS One	2019
31591191	Screening <i>Legionella</i> effectors for antiviral effects reveals Rab1 GTPase as a proviral factor coopted for tombusvirus replication.	Proc Natl Acad Sci U S A	2019
30625229	Recruitment of Vps34 PI3K and enrichment of PI3P phosphoinositide in the viral replication compartment is crucial for replication of a positive-strand RNA virus.	PLoS Pathogens	2019
31234777	Helitron distribution in Brassicaceae and whole Genome Helitron density as a character for distinguishing plant species.	BMC Bioinformatics	2019
31348886	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.	Cell	2019
29453938	Barley stripe mosaic virus infection requires PKA-mediated phosphorylation of Î³b for suppression of both RNA silencing and the host cell death response.	New Phytologist	2018
30030790	Structural Features of Broadly Neutralizing Antibodies and Rational Design of Vaccine.	Advances in Experimental Medicine and Biology	2018
29975771	Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.	PLoS Pathog	2018
29867235	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.	Nat Med	2018
30420505	Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.	Proc Natl Acad Sci U S A	2018
29746582	Assembly-hub function of ER-localized SNARE proteins in biogenesis of tombusvirus replication compartment.	PLoS Pathogens	2018
29066357	Barley Stripe Mosaic Virus Î³b Interacts with Glycolate Oxidase and Inhibits Peroxisomal ROS Production to Facilitate Virus Infection.	Molecular Plant	2018
29540800	Hsc70-2 is required for Beet black scorch virus infection through interaction with replication and capsid proteins.	Scientific Reports	2018
28100609	Sterol Binding by the Tombusviral Replication Proteins Is Essential for Replication in Yeast and Plants.	Journal of Virology	2017
28445724	Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.	Cell Rep	2017
29281818	Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models.	Cell Reports	2017
28275193	Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.	Journal of Virology	2017
27503072	An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.	J Exp Med	2016