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Author Details

Daria J Hazuda
Merck & Co. Inc.
1983
226
66
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36812345Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1.Sci Transl Med2023
37499664High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.Cell Chem Biol2023
35230978Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy.J Clin Invest2022
35348047"We are looking at the future right now": community acceptability of a home-based viral load test device in the context of HIV cure-related research with analytical treatment interruptions in the United States.HIV Res Clin Pract2022
35367399Development of a fully automated platform for agar-based measurement of viable bacterial growth.SLAS Technol2022
35491829Doravirine and Islatravir Have Complementary Resistance Profiles and Create a Combination with a High Barrier to Resistance.Antimicrob Agents Chemother2022
35654846Detection of cell-cell interactions via photocatalytic cell tagging.Nat Chem Biol2022
36543997Single cell multi-omic reference atlases of non-human primate immune tissues reveals CD102 as a biomarker for long-lived plasma cells.Commun Biol2022
35968737Participant experiences using novel home-based blood collection device for viral load testing in HIV cure trials with analytical treatment interruptionsHIV Res Clin Pract2022
35207719Preliminary Acceptability of a Home-Based Peripheral Blood Collection Device for Viral Load Testing in the Context of Analytical Treatment Interruptions in HIV Cure Trials: Results from a Nationwide Survey in the United States.J Pers Med2022
35139367Follicular T cells optimize the germinal center response to SARS-CoV-2 protein vaccination in mice.Cell Rep2022
35263097Call for Papers: Drug Resistance in Infectious Diseases and Beyond.ACS Infect Dis2022
33323024Safety, Immune, and Antiviral Effects of Pegylated Interferon Alpha 2b Administration in Antiretroviral Therapy-Suppressed Individuals: Results of Pilot Clinical Trial.AIDS Res Hum Retroviruses2021
33796087Improved Detection of HIV Gag p24 Protein Using a Combined Immunoprecipitation and Digital ELISA Method.Front Microbiol2021
33766889Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing.Proc Natl Acad Sci U S A2021
33596266SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development.PLoS Pathog2021
33693750Gag p24 Is a Marker of Human Immunodeficiency Virus Expression in Tissues and Correlates With Immune Response.J Infect Dis2021
33807734Primary Human Dendritic Cells and Whole-Blood Based Assays to Evaluate Immuno-Modulatory Properties of Heat-Killed Commensal Bacteria.Vaccines (Basel)2021
34570651Impact of HIV-1 Resistance-Associated Mutations on Susceptibility to Doravirine: Analysis of Real-World Clinical Isolates.Antimicrob Agents Chemother2021
34835271Vaccine Hyporesponse Induced by Individual Antibiotic Treatment in Mice and Non-Human Primates Is Diminished upon Recovery of the Gut Microbiome.Vaccines (Basel)2021
34251432Letter to the Editor in Response to Zhou et al.J Infect Dis2021
34054810Immunomodulation by the Commensal Microbiome During Immune-Targeted Interventions: Focus on Cancer Immune Checkpoint Inhibitor Therapy and Vaccination.Front Immunol2021
34111271Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit.J Infect Dis2021
34049356Comparable HIV suppression by pegylated-IFN-α2a or pegylated-IFN-α2b during a 4-week analytical treatment interruption.AIDS2021
33427012In Vitro Pharmacokinetic/Pharmacodynamic Modeling of HIV Latency Reversal by Novel HDAC Inhibitors Using an Automated Platform.SLAS Discov2021
33245088The application potential of machine learning and genomics for understanding natural product diversity, chemistry, and therapeutic translatability.Nat Prod Rep2021
31621289Rational Design of Doravirine: From Bench to Patients.ACS Infect Dis2020
34458775The chemical biology of coronavirus host-cell interactions.RSC Chem Biol2020
32703745Immunogenicity generated by mRNA vaccine encoding VZV gE antigen is comparable to adjuvanted subunit vaccine and better than live attenuated vaccine in nonhuman primates.Vaccine2020
32925358Review of Doravirine Resistance Patterns Identified in Participants During Clinical Development.J Acquir Immune Defic Syndr2020
32895573Recommendations for measuring HIV reservoir size in cure-directed clinical trials.Nat Med2020
32749732Design of a Multiuse Photoreactor To Enable Visible-Light Photocatalytic Chemical Transformations and Labeling in Live Cells.Chembiochem2020
32295913Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat.J Virol2020
31175822Once-Weekly Oral Dosing of MK-8591 Protects Male Rhesus Macaques From Intrarectal Challenge With SHIV109CP3.J Infect Dis2020
30778080PD-1 blockade potentiates HIV latency reversal ex vivo in CD4<sup>+</sup> T cells from ART-suppressed individuals.Nat Commun2019
31578289Differentiation into an Effector Memory Phenotype Potentiates HIV-1 Latency Reversal in CD4<sup>+</sup> T Cells.J Virol2019
31400112A deep learning genome-mining strategy for biosynthetic gene cluster prediction.Nucleic Acids Res2019
31541085Ultra-long-acting tunable biodegradable and removable controlled release implants for drug delivery.Nat Commun2019
29029095Identification of novel bifunctional HIV-1 reverse transcriptase inhibitors.J Antimicrob Chemother2018
29669853CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells.Sci Transl Med2018
29506608Long-acting formulations for the treatment of latent tuberculous infection: opportunities and challenges.Int J Tuberc Lung Dis2018
27889530Identification of proximal biomarkers of PKC agonism and evaluation of their role in HIV reactivation.Antiviral Res2017
28285916Discovery and optimization of 2-pyridinone aminal integrase strand transfer inhibitors for the treatment of HIV.Bioorg Med Chem Lett2017
29088734Active evolution of memory B-cells specific to viral gH/gL/pUL128/130/131 pentameric complex in healthy subjects with silent human cytomegalovirus infection.Oncotarget2017
28814661HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal.JCI Insight2017
27002074A long-acting formulation of the integrase inhibitor raltegravir protects humanized BLT mice from repeated high-dose vaginal HIV challenges.J Antimicrob Chemother2016
27669286Mechanistic Study of Common Non-Nucleoside Reverse Transcriptase Inhibitor-Resistant Mutations with K103N and Y181C Substitutions.Viruses2016
27206407In vivo analysis of the effect of panobinostat on cell-associated HIV RNA and DNA levels and latent HIV infection.Retrovirology2016
27219495Primer ID ultra-deep sequencing reveals dynamics of drug resistance-associated variants in breakthrough hepatitis C viruses: relevance to treatment outcome and resistance screening.Antivir Ther2016
27463679Latency reversal and viral clearance to cure HIV-1.Science2016
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Collaborators

Amy S Espeseth
Merck & Co., Inc.
Co-authored papers 25
Karam Mounzer
Co-authored papers 7
Pablo Tebas
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 7
Luis J Montaner
Wistar Institute
Co-authored papers 7
Rafick-Pierre Sekaly
Pathology Advanced Translational Research Unit, Emory University School of Medicine
Co-authored papers 6
Douglas D Richman
Center for AIDS Research, University of California San Diego
Co-authored papers 6
Steven G Deeks
University of California san francisco
Co-authored papers 5
Kalpit A Vora
Co-authored papers 5
Joseph J Eron
Co-authored papers 5
Daniel I S Rosenbloom
Merck & Co. Inc.
Co-authored papers 4
Martin Markowitz
Co-authored papers 4
Tracy L Diamond
Merck & Co. Inc.
Co-authored papers 4
Ziqiang Guan
Duke University Medical Center
Co-authored papers 4
Jacob D Estes
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 4
Marc Ferrer
National Institutes of Health, National Center for Advancing Translational Sciences
Co-authored papers 3
Honglin Zhou
Merck & Co., Inc.
Co-authored papers 3
David A Cooper
Co-authored papers 3
Frederic D Bushman
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 3
Jeffrey D Lifson
Frederick National Laboratory
Co-authored papers 3
Geoffrey D Hannigan
Merck & Co., Inc.
Co-authored papers 3
Bonaventura Clotet
IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 2
Frederick M Hecht
Co-authored papers 2
Andrew Emili
Boston University School of Medicine, Boston University
Co-authored papers 2
Zhiqiang An
Zhengzhou University
Co-authored papers 2
Dorit Donoviel
Translational Research Institute for Space Health
Co-authored papers 2
Yue-Ming Li
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
James E Bruce
Co-authored papers 2
Sharon R Lewin
The University of Melbourne at the Peter Doherty Institute for Infection and Immunity
Co-authored papers 2
Ian Frank
IF School of Medicine, University of Pennsylvania
Co-authored papers 2
Nicole L Sullivan
Co-authored papers 2
Release 1.2