Author details

Full Name

Kyle J Gaulton

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37161089	Interpreting non-coding disease-associated human variants using single-cell epigenomics.	Nat Rev Genet	2023
35840754	Characterizing cis-regulatory elements using single-cell epigenomics.	Nat Rev Genet	2023
37814896	Cardiovascular Disease Knowledge Portal: A Community Resource for Cardiovascular Disease Research.	Circ Genom Precis Med	2023
37582230	An Integrated Map of Cell Type-Specific Gene Expression in Pancreatic Islets.		2023
37808749	Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity.	medRxiv	2023
37986756	Genetic discovery and risk prediction for type 1 diabetes in individuals without high-risk HLA-DR3/DR4 haplotypes.		2023
37886436	Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity.	Res Sq	2023
37561710	Leveraging type 1 diabetes human genetic and genomic data in the T1D knowledge portal.	PLoS Biol	2023
37289818	Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral blood.	PLoS Genet	2023
36778506	An integrated map of cell type-specific gene expression in pancreatic islets.		2023
36778413	Leveraging type 1 diabetes human genetic and genomic data in the T1D Knowledge Portal.	bioRxiv	2023
36711922	Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes.	bioRxiv	2023
36940317	Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.	Diabetes	2023
37116182	Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433-448.	Diabetes	2023
36538063	High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic pathways of metabolic disease.		2023
37231096	Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.	Nat Genet	2023
37040771	Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.	Dev Cell	2023
37078927	Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.	Pancreas	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
36778047	Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.	Cell Genom	2022
34774128	A single-cell atlas of chromatin accessibility in the human genome.	Cell	2021
34012112	Interpreting type 1 diabetes risk with genetics and single-cell epigenomics.	Nature	2021
33795864	Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk.	Nat Genet	2021
33990324	Cardiac cell type-specific gene regulatory programs and disease risk association.	Sci Adv	2021
33983929	Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes.	PLoS Genetics	2021
33505025	Systematic analysis of binding of transcription factors to noncoding variants.	Nature	2021
33398137	Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.	Nature	2021
34789735	Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.	Nat Commun	2021
34616068	An atlas of gene regulatory elements in adult mouse cerebrum.	Nature	2021
34663987	Mutations and variants of ONECUT1 in diabetes.	Nat Med	2021
33164753	Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes.	Elife	2020
33037424	Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.	Nature	2020
31064983	Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk.	Nat Commun	2019
36643055	Neighborhoods to Nucleotides - Advances and gaps for an obesity disparities systems epidemiology model.	Curr Epidemiol Rep	2019
31779666	Common DNA sequence variation influences 3-dimensional conformation of the human genome.	Genome Biol	2019
31570892	Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits.	Nat Genet	2019
30604766	Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.	Nat Commun	2019
30918008	The long noncoding RNA <i>ROCKI</i> regulates inflammatory gene expression.	EMBO J	2019
30914061	Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data.	Genome Medicine	2019
29360107	Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2018
30407494	Shared genetic risk contributes to type 1 and type 2 diabetes etiology.	Human Molecular Genetics	2018
30240442	Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.	PLoS Med	2018
29750786	Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.	PLoS Genet	2018
29279374	Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.	Proc Natl Acad Sci U S A	2018
29412141	Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci.	Elife	2018
28132686	Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.	American Journal of Human Genetics	2017
28341696	A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.	Diabetes	2017
28498854	Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.	PLoS Genet	2017
28741265	Mechanisms of Type 2 Diabetes Risk Loci.	Current Diabetes Reports	2017
28566273	An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.	Diabetes	2017