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Author Details

Jerry A Stitzel
1985
85
35
PMIDPaper TitleJournal TitlePublished Year
36444815Testing Association of Previously Implicated Gene Sets and Gene-Networks in Nicotine Exposed Mouse Models with Human Smoking Phenotypes.Nicotine Tob Res2023
37216417Transcriptome-wide gene-gene interaction associations elucidate pathways and functional enrichment of complex traits.PLoS Genet2023
36477530Genetic diversity fuels gene discovery for tobacco and alcohol use.Nature2022
35752273Mutation of the α5 nicotinic acetylcholine receptor subunit increases ethanol and nicotine consumption in adolescence and impacts adult drug consumption.Neuropharmacology2022
35610565RCAN1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of Down syndrome, Alzheimer's disease, and normative aging.Journal of Neurodevelopmental Disorders2022
34159514The Intergenerational Transmission of Developmental Nicotine Exposure-Induced Neurodevelopmental Disorder-Like Phenotypes is Modulated by the Chrna5 D397N Polymorphism in Adolescent Mice.Behavior Genetics2021
34803779Genetic Modifiers of Oral Nicotine Consumption in Null Mutant Mice.Frontiers in Psychiatry2021
34737286An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions.Nat Commun2021
34270696DNA methylome perturbations: an epigenetic basis for the emergingly heritable neurodevelopmental abnormalities associated with maternal smoking and maternal nicotine exposureâ¿ .Biology of Reproduction2021
31930296The Role of A Priori-Identified Addiction and Smoking Gene Sets in Smoking Behaviors.Nicotine and Tobacco Research2020
32138755Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi of adolescent mice.Epigenetics and Chromatin2020
31404529Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.Biochemical Pharmacology2019
30742847Developmental nicotine exposure precipitates multigenerational maternal transmission of nicotine preference and ADHD-like behavioral, rhythmometric, neuropharmacological, and epigenetic anomalies in adolescent mice.Neuropharmacology2019
30564868The effects of oral nicotine administration and abstinence on sleep in male C57BL/6J mice.Psychopharmacology2019
30414940Serine residues in the α4 nicotinic acetylcholine receptor subunit regulate surface α4β2 receptor expression and clustering.Biochemical Pharmacology2019
29573323The interaction of the Chrna5 D398N variant with developmental nicotine exposure.Genes, Brain and Behavior2018
28032407CYP2A6 metabolism in the development of smoking behaviors in young adults.Addict Biol2018
30097758A novel genetic marker of decreased inflammation and improved survival after acute myocardial infarction.Basic Res Cardiol2018
28112735Nicotine reverses hypofrontality in animal models of addiction and schizophrenia.Nat Med2017
28398760Nicotine Impairs Macrophage Control of Mycobacterium tuberculosis.American Journal of Respiratory Cell and Molecular Biology2017
26239294Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans.Mol Psychiatry2016
26351737Nicotinic acetylcholine receptors: upregulation, age-related effects and associations with drug use.Genes, Brain and Behavior2016
25498233Natural genetic variability of the neuronal nicotinic acetylcholine receptor subunit genes in mice: Consequences and confounds.Neuropharmacology2015
26318101The β3 subunit of the nicotinic acetylcholine receptor: Modulation of gene expression and nicotine consumption.Neuropharmacology2015
26220977A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence.Hum Mol Genet2015
25911614Crucial role of nicotinic α5 subunit variants for Ca2+ fluxes in ventral midbrain neurons.FASEB Journal2015
25744161Maximizing the effect of an α7 nicotinic receptor PAM in a mouse model of schizophrenia-like sensory inhibition deficits.Brain Research2015
25704105Melatonin administration alters nicotine preference consumption via signaling through high-affinity melatonin receptors.Psychopharmacology2015
24462939Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.Brain Research2014
24953818Presynaptic GABAB autoreceptor regulation of nicotinic acetylcholine receptor mediated [(3)H]-GABA release from mouse synaptosomes.Biochemical Pharmacology2014
23691088Alternative CHRNB4 3'-UTRs mediate the allelic effects of SNP rs1948 on gene expression.PLoS ONE2013
23872218Functional characterization of SNPs in CHRNA3/B4 intergenic region associated with drug behaviors.Brain Research2013
22042774Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence.Hum Mol Genet2012
22868939Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.Arch Gen Psychiatry2012
22820272Diurnal variation in nicotine sensitivity in mice: role of genetic background and melatonin.Neuropharmacology2012
22820273Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors.Neuropharmacology2012
22633961Comparison of nicotine oral consumption and baseline anxiety measures in adolescent and adult C57BL/6J and C3H/Ibg mice.Behavioural Brain Research2012
22314319Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases.Neuroscience2012
20854418CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences.Genes, Brain and Behavior2011
21704022Recent advances in gene manipulation and nicotinic acetylcholine receptor biology.Biochemical Pharmacology2011
21079997Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence.Hum Genet2011
19760673Association of CHRN genes with "dizziness" to tobacco.American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics2010
20100906Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.Journal of Pharmacology and Experimental Therapeutics2010
20061993Chrna4 A529 knock-in mice exhibit altered nicotine sensitivity.Pharmacogenet Genomics2010
19139153Acetylcholine-stimulated [3H]GABA release from mouse brain synaptosomes is modulated by alpha4beta2 and alpha4alpha5beta2 nicotinic receptor subtypes.Molecular Pharmacology2009
19443489Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.Hum Mol Genet2009
19368846Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels.Brain Research2009
19259974Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.Am J Med Genet B Neuropsychiatr Genet2009
17981562Naturally occurring genetic variability in the nicotinic acetylcholine receptor alpha4 and alpha7 subunit genes and phenotypic diversity in humans and mice.Frontiers in Bioscience - Landmark2008
18606956The incentive salience of alcohol: translating the effects of genetic variant in CNR1.2008
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