|
| 36273330 | Epigenetic upregulation of Schlafen11 renders ⿨WNT- and SHH-activated medulloblastomas sensitive to cisplatin. | Neuro Oncol | 2023 |
| 36273330 | Epigenetic upregulation of Schlafen11 renders ⿨WNT- and SHH-activated medulloblastomas sensitive to cisplatin. | Neuro Oncol | 2023 |
| 37850658 | Unprecedented reactivity of polyamines with aldehydic DNA modifications: structural determinants of reactivity, characterization and enzymatic stability of adducts. | Nucleic Acids Res | 2023 |
| 37670571 | Real-time imaging of drug-induced trapping of cellular topoisomerases and poly(ADP-ribose) polymerase 1 at the single-molecule level. | Nucleic Acids Res | 2023 |
| 37600974 | R-loops, type I topoisomerases and cancer. | NAR Cancer | 2023 |
| 37706203 | Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency. | Neurooncol Adv | 2023 |
| 36972660 | HTLV-1 bZIP factor impairs DNA mismatch repair system. | Biochem Biophys Res Commun | 2023 |
| 37343696 | Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets. | Mol Cell Proteomics | 2023 |
| 37216280 | Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication. | Mol Cancer Ther | 2023 |
| 36715552 | Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes. | Cancer Discov | 2023 |
| 37024461 | Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes. | Nat Commun | 2023 |
| 36897562 | Glutamine protects mouse spermatogonial stem cells against NOX1-derived ROS for sustaining self-renewal division in vitro. | Development | 2023 |
| 37140427 | CellMinerCDB: NCATS Is a Web-Based Portal Integrating Public Cancer Cell Line Databases for Pharmacogenomic Explorations. | Cancer Res | 2023 |
| 36637483 | New Life of Topoisomerase I Inhibitors as Antibody-Drug Conjugate Warheads. | Clin Cancer Res | 2023 |
| 37010988 | A Phase I Study of a Combination of Liposomal Irinotecan and Veliparib in Solid Tumors. | Oncologist | 2023 |
| 37129502 | Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT. | Hum Mol Genet | 2023 |
| 37187895 | Editorial: The repair of DNA-protein crosslinks. | Front Mol Biosci | 2023 |
| 37057596 | BRCAness, Homologous Recombination Deficiencies, and Synthetic Lethality. | Cancer Res | 2023 |
| 37181631 | Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification. | RSC Chem Biol | 2023 |
| 36932053 | Synthesis and Biological Activities of 11- and 12-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 Inhibitors. | ChemMedChem | 2023 |
| 37296836 | Preclinical Models of Adrenocortical Cancer. | Cancers (Basel) | 2023 |
| 37353483 | Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex. | Nat Commun | 2023 |
| 37227187 | Targeting Replication Stress and Chemotherapy Resistance with a Combination of Sacituzumab Govitecan and Berzosertib: A Phase I Clinical Trial. | Clin Cancer Res | 2023 |
| 37670571 | Real-time imaging of drug-induced trapping of cellular topoisomerases and poly(ADP-ribose) polymerase 1 at the single-molecule level. | Nucleic Acids Res | 2023 |
| 37706203 | Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency. | Neurooncol Adv | 2023 |
| 37850658 | Unprecedented reactivity of polyamines with aldehydic DNA modifications: structural determinants of reactivity, characterization and enzymatic stability of adducts. | Nucleic Acids Res | 2023 |
| 37600974 | R-loops, type I topoisomerases and cancer. | NAR Cancer | 2023 |
| 37353483 | Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex. | Nat Commun | 2023 |
| 37024461 | Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes. | Nat Commun | 2023 |
| 37057596 | BRCAness, Homologous Recombination Deficiencies, and Synthetic Lethality. | Cancer Res | 2023 |
| 37216280 | Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication. | Mol Cancer Ther | 2023 |
| 37187895 | Editorial: The repair of DNA-protein crosslinks. | Front Mol Biosci | 2023 |
| 37343696 | Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets. | Mol Cell Proteomics | 2023 |
| 37181631 | Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification. | RSC Chem Biol | 2023 |
| 37010988 | A Phase I Study of a Combination of Liposomal Irinotecan and Veliparib in Solid Tumors. | Oncologist | 2023 |
| 37140427 | CellMinerCDB: NCATS Is a Web-Based Portal Integrating Public Cancer Cell Line Databases for Pharmacogenomic Explorations. | Cancer Res | 2023 |
| 36972660 | HTLV-1 bZIP factor impairs DNA mismatch repair system. | Biochem Biophys Res Commun | 2023 |
| 37296836 | Preclinical Models of Adrenocortical Cancer. | Cancers (Basel) | 2023 |
| 37227187 | Targeting Replication Stress and Chemotherapy Resistance with a Combination of Sacituzumab Govitecan and Berzosertib: A Phase I Clinical Trial. | Clin Cancer Res | 2023 |
| 37129502 | Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT. | Hum Mol Genet | 2023 |
| 36715552 | Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes. | Cancer Discov | 2023 |
| 36932053 | Synthesis and Biological Activities of 11- and 12-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 Inhibitors. | ChemMedChem | 2023 |
| 36637483 | New Life of Topoisomerase I Inhibitors as Antibody-Drug Conjugate Warheads. | Clin Cancer Res | 2023 |
| 36897562 | Glutamine protects mouse spermatogonial stem cells against NOX1-derived ROS for sustaining self-renewal division in vitro. | Development | 2023 |
| 34534680 | Molecular Subtypes of Primary SCLC Tumors and Their Associations With Neuroendocrine and Therapeutic Markers. | J Thorac Oncol | 2022 |
| 35463961 | SUMO: A Swiss Army Knife for Eukaryotic Topoisomerases. | Front Mol Biosci | 2022 |
| 35395253 | Nucleosome destabilization by polyamines. | Arch Biochem Biophys | 2022 |
| 35768579 | Structural, molecular, and functional insights into Schlafen proteins. | Exp Mol Med | 2022 |
| 35903760 | SLFN11's surveillance role in protein homeostasis. | Oncoscience | 2022 |
| 36030054 | Functional characterization of two variants of mitochondrial topoisomerase TOP1MT that impact regulation of the mitochondrial genome. | J Biol Chem | 2022 |