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Author Details

Derek L Stirewalt
Fred Hutchinson Cancer Center
1992
80
41
PMIDPaper TitleJournal TitlePublished Year
37967363R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts.Cancer Res2024
36927800Verification of prognostic expression biomarkers is improved by examining enriched leukemic blasts rather than mononuclear cells from acute myeloid leukemia patients.Biomark Res2023
37021537Examining the impact of age on the prognostic value of ELN-2017 and ELN-2022 acute myeloid leukemia risk stratifications: a report from the SWOG Cancer Research Network.Haematologica2023
37267439Characteristics and prognostic impact of IDH mutations in AML: a COG, SWOG, and ECOG analysis.Blood Adv2023
36815378Comprehensive molecular and clinical characterization of <i>NUP98</i> fusions in pediatric acute myeloid leukemia.Haematologica2023
36795987Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia.J Clin Oncol2023
34780648MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis.Blood2022
34861039Coordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome.Blood2022
35138909Targeting an alternate Wilms' tumor antigen 1 peptide bypasses immunoproteasome dependency.Sci Transl Med2022
34551388NCCN Guidelines® Insights: Older Adult Oncology, Version 1.2021.J Natl Compr Canc Netw2021
33719833Associations between complete remission and 2- to 3-year survival following 7â¿¿+â¿¿3 induction for acute myeloid leukemia.Leuk Lymphoma2021
32817791AML risk stratification models utilizing ELN-2017 guidelines and additional prognostic factors: a SWOG report.Biomark Res2020
30315233Second cycle remission achievement with 7+3 and survival in adults with newly diagnosed acute myeloid leukemia: analysis of recent SWOG trials.Leukemia2019
29172682Impact of Specimen Heterogeneity on Biomarkers in Repository Samples from Patients with Acute Myeloid Leukemia: A SWOG Report.Biopreserv Biobank2018
28555084Mitoxantrone, etoposide and cytarabine following epigenetic priming with decitabine in adults with relapsed/refractory acute myeloid leukemia or other high-grade myeloid neoplasms: a phase 1/2 study.Leukemia2017
27133827Effect of measurable ('minimal') residual disease (MRD) information on prediction of relapse and survival in adult acute myeloid leukemia.Leukemia2016
26621847Immobilized Metal Affinity Chromatography Coupled to Multiple Reaction Monitoring Enables Reproducible Quantification of Phospho-signaling.Mol Cell Proteomics2016
27799507NCCN Guidelines Insights: Older Adult Oncology, Version 2.2016.J Natl Compr Canc Netw2016
25713434Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: a SWOG and UK National Cancer Research Institute/Medical Research Council report.J Clin Oncol2015
26397705Transcriptome Profiling of Pediatric Core Binding Factor AML.PLoS One2015
25996682Identification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemia.Epigenetics2015
24453295Senior adult oncology, version 2.2014: clinical practice guidelines in oncology .J Natl Compr Canc Netw2014
25267620Quantitative and stoichiometric analysis of the microRNA content of exosomes.Proc Natl Acad Sci U S A2014
25385641Sample processing obscures cancer-specific alterations in leukemic transcriptomes.Proc Natl Acad Sci U S A2014
24786392Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AML.Blood Cancer J2014
24720749The human salivary proteome is radiation responsive.Radiat Res2014
24453296Hematopoietic stem cell transplantation for hematologic malignancies in older adults: geriatric principles in the transplant clinic.J Natl Compr Canc Netw2014
22722750Mutations in the DNMT3A exon 23 independently predict poor outcome in older patients with acute myeloid leukemia: a SWOG report.Leukemia2013
24086639MicroRNA-150 expression induces myeloid differentiation of human acute leukemia cells and normal hematopoietic progenitors.PLoS One2013
23829510A model for prediction of FLT3-ITD and NPM1 (without FLT3-ITD) positivity in patients with newly diagnosed acute myeloid leukaemia.Br J Haematol2013
23967110The prognostic significance of IRF8 transcripts in adult patients with acute myeloid leukemia.PLoS One2013
22529286Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen.Blood2012
22767498Five-group cytogenetic risk classification, monosomal karyotype, and outcome after hematopoietic cell transplantation for MDS or acute leukemia evolving from MDS.Blood2012
22900933Proteomic classification of acute leukemias by alignment-based quantitation of LC-MS/MS data sets.J Proteome Res2012
21268710Identification of radiation-induced expression changes in nonimmortalized human T cells.Radiat Res2011
23675234Comparison of Two Methods for Detecting Alternative Splice Variants Using GeneChip(®) Exon Arrays.Int J Biomed Sci2011
21848522Clofarabine with high dose cytarabine and granulocyte colony-stimulating factor (G-CSF) priming for relapsed and refractory acute myeloid leukaemia.Br J Haematol2011
21873548Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG.Blood2011
21383194Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma.Proc Natl Acad Sci U S A2011
21388270Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISA.Radiat Res2011
20376086Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.Leukemia2010
20541027Tumor necrosis factor polymorphism affects transplantation outcome in patients with myelodysplastic syndrome but not in those with chronic myelogenous leukemia, independent of the presence of HLA-DR15.Biol Blood Marrow Transplant2010
20306247Receptor tyrosine kinase alterations in AML - biology and therapy.Cancer Treat Res2010
20413658Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group.Blood2010
18596738Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.Leukemia2009
19698932Gene expression changes in normal haematopoietic cells.Best Pract Res Clin Haematol2009
19625708The preferentially expressed antigen in melanoma (PRAME) inhibits myeloid differentiation in normal hematopoietic and leukemic progenitor cells.Blood2009
19304957Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group.Blood2009
18927435Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia.Blood2009
18162123Tumour necrosis factor-induced gene expression in human marrow stroma: clues to the pathophysiology of MDS?Br J Haematol2008
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Collaborators

Fred Hutchinson Cancer Center
Co-authored papers 40
Fred Hutchinson Cancer Research Centre
Co-authored papers 32
Keck School of Medicine, University of Southern California
Co-authored papers 12
Fred Hutchinson Cancer Center.
Co-authored papers 7
Clinical Research Division, Fred Hutchinson Cancer Research Center
Co-authored papers 6
Co-authored papers 3
Children's Hospital of Philadelphia
Co-authored papers 3
Co-authored papers 3
AbbVie Inc.
Co-authored papers 3
Co-authored papers 3
Feinberg School of Medicine, Northwestern University
Co-authored papers 3
University of Michigan ann arbor
Co-authored papers 3
Memorial Sloan-Kettering Cancer Center
Co-authored papers 2
Fred Hutchinson Cancer Research Center, University of Washington
Co-authored papers 2
St. Jude Children's Research Hospital
Co-authored papers 2
National Cancer Institute
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Clinical Research Division, Fred Hutchinson Cancer Center
Co-authored papers 2
Fred Hutchinson Cancer Center
Co-authored papers 2
Georgia Cancer Center
Co-authored papers 2
Center for Epigenetics, Van Andel Research Institute
Co-authored papers 2
MD Anderson Cancer Center
Co-authored papers 2
Central Texas Veterans Healthcare System
Co-authored papers 1
University of Washington, USA Brotman Baty Institute for Precision Medicine
Co-authored papers 1
National Cancer Institute
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Fred Hutchinson Cancer Center
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
University of Utah Huntsman Cancer Institute
Co-authored papers 1
University of Washington and Fred Hutchinson Cancer Research Center
Co-authored papers 1