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Author Details

Samuel Kelly
2004
38
27
PMIDPaper TitleJournal TitlePublished Year
31954175The regulation of p53, p38 MAPK, JNK and XBP-1s by sphingosine kinases in human embryonic kidney cells.Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids2020
30300671Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice.2019
31638789Analysis of 1-Deoxysphingoid Bases and Their -Acyl Metabolites and Exploration of Their Occurrence in Some Food Materials.Journal of Agricultural and Food Chemistry2019
29632068Eleven residues determine the acyl chain specificity of ceramide synthases.Journal of Biological Chemistry2018
30224516Native and Polyubiquitinated Forms of Dihydroceramide Desaturase Are Differentially Linked to Human Embryonic Kidney Cell Survival.Molecular and Cellular Biology2018
28087695Novel Interconnections in Lipid Metabolism Revealed by Overexpression of Sphingomyelin Synthase-1.Journal of Biological Chemistry2017
28320857Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein.Journal of Biological Chemistry2017
29163475Critical Role for Very-Long Chain Sphingolipids in Invariant Natural Killer T Cell Development and Homeostasis.Frontiers in Immunology2017
25598080Biomarkers of NAFLD progression: a lipidomics approach to an epidemic.J Lipid Res2015
24064337Neuronal accumulation of glucosylceramide in a mouse model of neuronopathic Gaucher disease leads to neurodegeneration.Human Molecular Genetics2014
24163422Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipid N-acyl chain.Journal of Lipid Research2014
23283968Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain.Journal of Biological Chemistry2013
22144673Acyl chain specificity of ceramide synthases is determined within a region of 150 residues in the Tram-Lag-CLN8 (TLC) domain.Journal of Biological Chemistry2012
22539345Modulation of ceramide synthase activity via dimerization.Journal of Biological Chemistry2012
23021221Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses.Cell2012
23110086Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction.PLoS One2012
21705317Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels.J Biol Chem2011
21415121A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences.Journal of Lipid Research2011
21586681Factors to consider in using [U-C]palmitate for analysis of sphingolipid biosynthesis by tandem mass spectrometry.Journal of Lipid Research2011
20671299Lipidomics reveals a remarkable diversity of lipids in human plasma.J Lipid Res2010
20876532Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy.J Biol Chem2010
20574076Subcellular organelle lipidomics in TLR-4-activated macrophages.J Lipid Res2010
19029065Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease.J Lipid Res2009
19362163Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology.2009
19036716Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers.Journal of Lipid Research2009
19536577Characterization of mutant serine palmitoyltransferase 1 in LY-B cells.Lipids2009
18790777N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing.Molecular Cancer Therapeutics2008
18644793Human cytomegalovirus regulates bioactive sphingolipids.Journal of Biological Chemistry2008
17008424The cell surface glycosphingolipids SSEA-3 and SSEA-4 are not essential for human ESC pluripotency.Stem Cells2007
17954214Structure-specific, quantitative methods for analysis of sphingolipids by liquid chromatography-tandem mass spectrometry: "inside-out" sphingolipidomics.Methods in Enzymology2007
17196738Steroidogenic factor-1 is a sphingolipid binding protein.Mol Cell Endocrinol2007
16877527Effects of sphingosine-1-phosphate and ceramide-1-phosphate on rat intestinal smooth muscle cells: implications for postoperative ileus.FASEB Journal2006
17052686Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy.2006
16782891Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide.Molecular and Cellular Biology2006
17130506Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy.Diabetes2006
15894491Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry.Methods2005
14570870Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis.J Biol Chem2004
15210766Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity.Journal of Immunology2004
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