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Author Details

Beatriz M A Fontoura
University of Texas Southwestern Medical Center
1990
60
36
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37085480Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex.Nat Commun2023
37738983Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.Cell Host Microbe2023
37578863Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly.Cell Rep2023
35908311Viral-host interactions during splicing and nuclear export of influenza virus mRNAs.Curr Opin Virol2022
35704758Nuclear speckle integrity and function require TAO2 kinase.Proc Natl Acad Sci U S A2022
34260245Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein.J Med Chem2021
33547084Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression.Sci Adv2021
32240278Chemical intervention of influenza virus mRNA nuclear export.PLoS Pathog2020
33269701Viral-induced alternative splicing of host genes promotes influenza replication.Elife2020
33097660SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.Proc Natl Acad Sci U S A2020
32917881Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway.Nat Commun2020
30876848Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination.Neuron2019
31435012DEAD-box ATPases are global regulators of phase-separated organelles.Nature2019
31263181Structural basis for influenza virus NS1 protein block of mRNA nuclear export.Nat Microbiol2019
29610492Günter Blobel 1936-2018.Nat Struct Mol Biol2018
29866401Editorial overview: The cell nucleus: Dynamic interplay of shape and function.Curr Opin Cell Biol2018
30258002Influenza Virus NS1 Protein-RNA Interactome Reveals Intron Targeting.J Virol2018
29921878Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing.Nat Commun2018
30538201Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.Proc Natl Acad Sci U S A2018
28067239Corrigendum: Influenza virus mRNA trafficking through host nuclear speckles.Nat Microbiol2017
28953980Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.PLoS Pathog2017
26735921UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages.PLoS Pathog2016
27610561Gating Immunity and Death at the Nuclear Pore Complex.Cell2016
27572970Influenza virus mRNA trafficking through host nuclear speckles.Nat Microbiol2016
26631972Sec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo.Sci Rep2015
24289861Viral subversion of nucleocytoplasmic trafficking.Traffic2014
25232931Primate-specific miR-576-3p sets host defense signalling threshold.Nat Commun2014
24530809Nuclear trafficking in health and disease.Curr Opin Cell Biol2014
23930152SAR Based Optimization of a 4-Quinoline Carboxylic Acid Analog with Potent Anti-Viral Activity.ACS Med Chem Lett2013
23825951Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.PLoS Pathog2013
23872491Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export.Viruses2013
22355110PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium.Proc Natl Acad Sci U S A2012
23244761Shaping the p53 response with nucleoporins.Mol Cell2012
22876275Host modulators of H1N1 cytopathogenicity.PLoS One2012
22312003Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.J Cell Biol2012
21909097Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.Nat Chem Biol2011
21965294Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.Mol Biol Cell2011
20081840The Nup107-160 complex and gamma-TuRC regulate microtubule polymerization at kinetochores.Nat Cell Biol2010
20584882The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands.J Exp Med2010
19745842Vesicular stomatitis virus inhibits mitotic progression and triggers cell death.EMBO Rep2009
18337511NFAR-1 and -2 modulate translation and are required for efficient host defense.Proc Natl Acad Sci U S A2008
19000832Nucleoporin levels regulate cell cycle progression and phase-specific gene expression.Dev Cell2008
17435768Structure-based design of a pathway-specific nuclear import inhibitor.Nat Struct Mol Biol2007
17981117Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite.Cell2007
17267598Influenza virus targets the mRNA export machinery and the nuclear pore complex.Proc Natl Acad Sci U S A2007
16546098The nucleoporin Nup96 is required for proper expression of interferon-regulated proteins and functions.Immunity2006
16807356The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly.Mol Biol Cell2006
16935004Nuclear export assays for poly(A) RNAs.Methods2006
15629720VSV disrupts the Rae1/mrnp41 mRNA nuclear export pathway.Mol Cell2005
16036565Viral interactions with the nuclear transport machinery: discovering and disrupting pathways.IUBMB Life2005
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Co-authored papers 9
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Co-authored papers 6
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University of Texas Southwestern Medical Center
Co-authored papers 3
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Co-authored papers 3
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Co-authored papers 3
University of California San Francisco
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Co-authored papers 2
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Co-authored papers 2
University of Iowa
Co-authored papers 2
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Co-authored papers 2
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