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Author Details
Full Name
Beatriz M A Fontoura
Affiliation
University of Texas Southwestern Medical Center
ORCID
Career Start Year
1990
Papers
60
H Index
36
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37085480
Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex.
Nat Commun
2023
37738983
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.
Cell Host Microbe
2023
37578863
Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly.
Cell Rep
2023
35908311
Viral-host interactions during splicing and nuclear export of influenza virus mRNAs.
Curr Opin Virol
2022
35704758
Nuclear speckle integrity and function require TAO2 kinase.
Proc Natl Acad Sci U S A
2022
34260245
Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein.
J Med Chem
2021
33547084
Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression.
Sci Adv
2021
32240278
Chemical intervention of influenza virus mRNA nuclear export.
PLoS Pathog
2020
33269701
Viral-induced alternative splicing of host genes promotes influenza replication.
Elife
2020
33097660
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.
Proc Natl Acad Sci U S A
2020
32917881
Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway.
Nat Commun
2020
30876848
Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination.
Neuron
2019
31435012
DEAD-box ATPases are global regulators of phase-separated organelles.
Nature
2019
31263181
Structural basis for influenza virus NS1 protein block of mRNA nuclear export.
Nat Microbiol
2019
29610492
Günter Blobel 1936-2018.
Nat Struct Mol Biol
2018
29866401
Editorial overview: The cell nucleus: Dynamic interplay of shape and function.
Curr Opin Cell Biol
2018
30258002
Influenza Virus NS1 Protein-RNA Interactome Reveals Intron Targeting.
J Virol
2018
29921878
Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing.
Nat Commun
2018
30538201
Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc Natl Acad Sci U S A
2018
28067239
Corrigendum: Influenza virus mRNA trafficking through host nuclear speckles.
Nat Microbiol
2017
28953980
Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.
PLoS Pathog
2017
26735921
UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages.
PLoS Pathog
2016
27610561
Gating Immunity and Death at the Nuclear Pore Complex.
Cell
2016
27572970
Influenza virus mRNA trafficking through host nuclear speckles.
Nat Microbiol
2016
26631972
Sec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo.
Sci Rep
2015
24289861
Viral subversion of nucleocytoplasmic trafficking.
Traffic
2014
25232931
Primate-specific miR-576-3p sets host defense signalling threshold.
Nat Commun
2014
24530809
Nuclear trafficking in health and disease.
Curr Opin Cell Biol
2014
23930152
SAR Based Optimization of a 4-Quinoline Carboxylic Acid Analog with Potent Anti-Viral Activity.
ACS Med Chem Lett
2013
23825951
Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.
PLoS Pathog
2013
23872491
Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export.
Viruses
2013
22355110
PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium.
Proc Natl Acad Sci U S A
2012
23244761
Shaping the p53 response with nucleoporins.
Mol Cell
2012
22876275
Host modulators of H1N1 cytopathogenicity.
PLoS One
2012
22312003
Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.
J Cell Biol
2012
21909097
Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.
Nat Chem Biol
2011
21965294
Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.
Mol Biol Cell
2011
20081840
The Nup107-160 complex and gamma-TuRC regulate microtubule polymerization at kinetochores.
Nat Cell Biol
2010
20584882
The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands.
J Exp Med
2010
19745842
Vesicular stomatitis virus inhibits mitotic progression and triggers cell death.
EMBO Rep
2009
18337511
NFAR-1 and -2 modulate translation and are required for efficient host defense.
Proc Natl Acad Sci U S A
2008
19000832
Nucleoporin levels regulate cell cycle progression and phase-specific gene expression.
Dev Cell
2008
17435768
Structure-based design of a pathway-specific nuclear import inhibitor.
Nat Struct Mol Biol
2007
17981117
Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite.
Cell
2007
17267598
Influenza virus targets the mRNA export machinery and the nuclear pore complex.
Proc Natl Acad Sci U S A
2007
16546098
The nucleoporin Nup96 is required for proper expression of interferon-regulated proteins and functions.
Immunity
2006
16807356
The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly.
Mol Biol Cell
2006
16935004
Nuclear export assays for poly(A) RNAs.
Methods
2006
15629720
VSV disrupts the Rae1/mrnp41 mRNA nuclear export pathway.
Mol Cell
2005
16036565
Viral interactions with the nuclear transport machinery: discovering and disrupting pathways.
IUBMB Life
2005
1 - 50 of 60
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