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Author Details

Grigore Pintilie
Stanford University
2009
52
23
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36928031Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.Nat Commun2023
37935678Structural insights into the modulation of coronavirus spike tilting and infectivity by hinge glycans.Nat Commun2023
37645939CryoEM structures of the human CLC-2 voltage gated chloride channel reveal a ball and chain gating mechanism.bioRxiv2023
37419099Diagnosing and treating issues in cryo-EM map-derived models.Structure2023
37116473Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.Cell2023
36824920Integrated analyses reveal a hinge glycan regulates coronavirus spike tilting and virus infectivity.Res Sq2023
36660826Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.Nucleic Acids Res2023
35233453Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia.ACS Cent Sci2022
35836020Three-dimensional structure-guided evolution of a ribosome with tethered subunits.Nat Chem Biol2022
36474933Electron microscopy holdings of the Protein Data Bank: the impact of the resolution revolution, new validation tools, and implications for the future.Biophys Rev2022
36493755Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.Cell2022
36067294Topological crossing in the misfolded <i>Tetrahymena</i> ribozyme resolved by cryo-EM.Proc Natl Acad Sci U S A2022
35121661Cryo-ET of <i>Toxoplasma</i> parasites gives subnanometer insight into tubulin-based structures.Proc Natl Acad Sci U S A2022
33411789The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.PLoS Pathog2021
33744287Evolution of standardization and dissemination of cryo-EM structures and data jointly by the community, PDB, and EMDB.J Biol Chem2021
33542514Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge.Nat Methods2021
34977676Cryo-EM analysis of Ebola virus nucleocapsid-like assembly.STAR Protoc2021
34473085Validation, analysis and annotation of cryo-EM structures.Acta Crystallogr D Struct Biol2021
34735239Mapping the catalytic conformations of an assembly-line polyketide synthase module.Science2021
34381213Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 ÿ resolution.Nature2021
34426697Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome.Nat Struct Mol Biol2021
34652947Complete three-dimensional structures of the Lon protease translocating a protein substrate.Sci Adv2021
34563541Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease.J Biol Chem2021
32170016Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.Proc Natl Acad Sci U S A2020
34192263A 3.4-ÿ cryo-electron microscopy structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles.QRB Discov2020
32042190Measurement of atom resolvability in cryo-EM maps with Q-scores.Nat Methods2020
33139928Resolving individual atoms of protein complex by cryo-electron microscopy.Cell Res2020
33028525Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V<sub>o</sub> complex.Sci Adv2020
32859924Publisher Correction: A glycoprotein B-neutralizing antibody structure at 2.8 ÿ uncovers a critical domain for herpesvirus fusion initiation.Nat Commun2020
32743589Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome.bioRxiv2020
32997652Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer.PLoS Biol2020
32817943A 3.4-ÿ cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles.bioRxiv2020
32616928Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.Nat Methods2020
32811830A glycoprotein B-neutralizing antibody structure at 2.8⿿ÿ uncovers a critical domain for herpesvirus fusion initiation.Nat Commun2020
30595457Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events.Structure2019
31740854Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions.Nat Struct Mol Biol2019
31796736Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7⿿ÿ resolution.Nat Commun2019
31447288Segmentation and Comparative Modeling in an 8.6-ÿ Cryo-EM Map of the Singapore Grouper Iridovirus.Structure2019
30955883The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.Cell2019
30814678Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.Cell Res2019
30894496Cryo-EM structures of <i>Helicobacter pylori</i> vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.Proc Natl Acad Sci U S A2019
29526695The 3.5-ÿ CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase V<sub>o</sub> Proton Channel.Mol Cell2018
30144506Assessment of structural features in Cryo-EM density maps using SSE and side chain Z-scores.J Struct Biol2018
30114512The first single particle analysis Map Challenge: A summary of the assessments.J Struct Biol2018
29474922Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.Cell2018
28844863Structural and Functional Impacts of ER Coactivator Sequential Recruitment.Mol Cell2017
26743049Resolution and Probabilistic Models of Components in CryoEM Maps of Mature P22 Bacteriophage.Biophys J2016
26578576EMDataBank unified data resource for 3DEM.Nucleic Acids Res2016
25728767Structure of a biologically active estrogen receptor-coactivator complex on DNA.Mol Cell2015
22696409Comparison of Segger and other methods for segmentation and rigid-body docking of molecular components in cryo-EM density maps.Biopolymers2012
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Collaborators

Wah Chiu
Stanford University
Co-authored papers 45
Michael F Schmid
Stanford University
Co-authored papers 14
Rhiju Das
Stanford University School of Medicine
Co-authored papers 6
Steven J Ludtke
Baylor College of Medicine
Co-authored papers 5
Catherine L Lawson
Institute for Quantitative Biomedicine, State University of New Jersey
Co-authored papers 4
Alexander Leitner
ETH Zurich
Co-authored papers 3
Ardan Patwardhan
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 3
Helen M Berman
The State University of New Jersey
Co-authored papers 3
David A Bushnell
Stanford University
Co-authored papers 3
Judith Frydman
Stanford University
Co-authored papers 3
Brian P Hudson
The State University of New Jersey
Co-authored papers 2
Ralph S Baric
University of North Carolina
Co-authored papers 2
Gaya K Amarasinghe
Washington University School of Medicine at St. Louis
Co-authored papers 2
John D Westbrook
The State University of New Jersey
Co-authored papers 2
Jennifer M Binning
H. Lee Moffitt Cancer Center and Research Institute
Co-authored papers 2
Bert W O'Malley
Center for Coregulator Research, Baylor College of Medicine
Co-authored papers 2
Matthew L Baker
McGovern Medical School at the University of Texas Health Science Center
Co-authored papers 2
Charles E Foulds
Co-authored papers 2
Daisy W Leung
Washington University School of Medicine
Co-authored papers 2
Gunnar F Schr??der
Institute of Biological Information Processing (Structural Biochemistry)
Co-authored papers 1
Henry van den Bedem
University of California San Francisco
Co-authored papers 1
Sagar D Khare
The State University of New Jersey
Co-authored papers 1
J. B Heymann
Frederick National Laboratory for Cancer Research, Inc.
Co-authored papers 1
Thomas D Goddard
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 1
Peng Zhao
Co-authored papers 1
Renzhi Cao
Pacific Lutheran University
Co-authored papers 1
Eugene Palovcak
University of California San Francisco
Co-authored papers 1
Priya Luthra
Trudeau Institute
Co-authored papers 1
Jean-Paul Armache
Center for Eukaryotic Gene Regulation, Pennsylvania State University, University Park
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Release 1.2