Author details

Full Name

Claes Wadelius

Affiliation

ORCID

Career Start Year

1988

Papers

136

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36697832	Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.	Nature	2023
35205761	Machine Learning-Based Analysis of Glioma Grades Reveals Co-Enrichment.	Cancers	2022
35388090	scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation.	Sci Rep	2022
36198307	Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues.	Cell Rep Med	2022
34520261	The Thioesterase as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver.	OMICS A Journal of Integrative Biology	2021
34171462	Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding.	Biochimica et Biophysica Acta - Gene Regulatory Mechanisms	2021
34282050	Functional annotation of noncoding mutations in cancer.	Life Science Alliance	2021
33785712	A non-coding cancer mutation disrupting an HNF4Î± binding motif affects an enhancer regulating genes associated to the progression of liver cancer.	Experimental Oncology	2021
34099540	Multifaceted regulation of hepatic lipid metabolism by YY1.	Life Science Alliance	2021
33119937	Single nucleus transcriptomics data integration recapitulates the major cell types in human liver.	Hepatology Research	2021
34521259	Genome-wide association study of liver enzyme elevation in rheumatoid arthritis patients starting methotrexate.	Pharmacogenomics	2021
31928966	rs953413 Regulates Polyunsaturated Fatty Acid Metabolism by Modulating ELOVL2 Expression.	iScience	2020
32433479	Integration of whole-body [F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.	Scientific Reports	2020
32080354	Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment.	Pharmacogenomics J	2020
32181701	A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver.	OMICS	2020
30711515	Pandemrix-induced narcolepsy is associated with genes related to immunity and neuronal survival.	eBioMedicine	2019
31776441	Author Correction: Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes.	Scientific Reports	2019
31557715	Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation.	iScience	2019
31501611	Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.	Nature Medicine	2019
31273253	Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes.	Scientific Reports	2019
30804403	Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases.	Scientific Reports	2019
27932482	PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c.	Nucleic Acids Research	2017
27577861	Genetic prevention of hepatitis C virus-induced liver fibrosis by allele-specific downregulation of MERTK.	Hepatology Research	2017
28084903	Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population.	Pharmacogenomics	2017
27625394	Maps of context-dependent putative regulatory regions and genomic signal interactions.	Nucleic Acids Research	2016
26847243	Novel regulatory variant detected on the VKORC1 haplotype that is associated with warfarin dose.	Pharmacogenomics	2016
27174533	A Significant Regulatory Mutation Burden at a High-Affinity Position of the CTCF Motif in Gastrointestinal Cancers.	Human Mutation	2016
27126307	Allele-specific transcription factor binding in liver and cervix cells unveils many likely drivers of GWAS signals.	Genomics	2016
26993500	Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression.	Hum Genet	2016
26817450	Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels.	Lipids in Health and Disease	2016
27488176	Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy.	Pharmacogenomics	2016
26195988	lobChIP: from cells to sequencing ready ChIP libraries in a single day.	Epigenetics and Chromatin	2015
25881024	Different distribution of histone modifications in genes with unidirectional and bidirectional transcription and a role of CTCF and cohesin in directing transcription.	BMC Genomics	2015
25111868	Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells.		2014
23617333	Best vitelliform macular dystrophy in a Swedish family: genetic analysis and a seven-year follow-up of photodynamic treatment of a young boy with choroidal neovascularization.	Acta Ophthalmologica	2014
24771338	Nucleosome regulatory dynamics in response to TGFÎ².	Nucleic Acids Res	2014
23467860	Genetic determinants of dabigatran plasma levels and their relation to bleeding.	Circulation	2013
24206787	ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer.	BMC Medical Genomics	2013
22248020	A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements.	Algorithms Mol Biol	2012
22242188	Combinations of histone modifications mark exon inclusion levels.	PLoS ONE	2012
22011431	Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa.	BMC Cancer	2011
20534969	Integrative epigenomic and genomic analysis of malignant pheochromocytoma.	Exp Mol Med	2010
19669598	Two polypyrimidine tracts in the nitric oxide synthase 2 gene: similar regulatory sequences with different properties.	Molecular Biology Reports	2010
20707885	SICTIN: Rapid footprinting of massively parallel sequencing data.	BioData Min	2010
20835238	Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.	Nat Genet	2010
20016685	ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.	PLoS Biol	2009
19451166	Identification of candidate regulatory SNPs by combination of transcription-factor-binding site prediction, SNP genotyping and haploChIP.	Nucleic Acids Research	2009
19687145	Nucleosomes are well positioned in exons and carry characteristic histone modifications.	Genome Res	2009
19292868	Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection.	FEBS J	2009
19276669	Histone H3 lysine 27 trimethylation in adult differentiated colon associated to cancer DNA hypermethylation.	Epigenetics	2009