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Author Details

Leslie Cope
Johns Hopkins University School of Medicine
2003
129
50
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36534524Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial.Clin Cancer Res2023
37218167Detecting aberrant DNA methylation in Illumina DNA methylation arrays: a toolbox and recommendations for its use.Epigenetics2023
37039321Multiplex Digital Methylation-Specific PCR for Noninvasive Screening of Lung Cancer.Adv Sci (Weinh)2023
36919699HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation.J Clin Invest2023
36811956Increasing the Capture Rate of Circulating Tumor DNA in Unaltered Plasma Using Passive Microfluidic Mixer Flow Cells.Langmuir2023
34492116A semiparametric isotonic regression model for skewed distributions with application to DNA-RNA-protein analysis.Biometrics2022
36463226A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence.Clin Epigenetics2022
36046124Development of an automated liquid biopsy assay for methylated markers in advanced breast cancer.Cancer Res Commun2022
36206311Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis.Cancer Res2022
33666134DNA-methylation for the detection and distinction of 19 human malignancies.Epigenetics2022
34021745Jutils: a visualization toolkit for differential alternative splicing events.Bioinformatics2021
33520697HEYL Regulates Neoangiogenesis Through Overexpression in Both Breast Tumor Epithelium and Endothelium.Front Oncol2021
33491650Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer.Elife2021
34907910Multicenter randomized phase II trial of atezolizumab with or without cobimetinib in biliary tract cancers.J Clin Invest2021
34396532Mutation and methylation profiles of ectopic and eutopic endometrial tissues.J Pathol2021
34341513CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer.Oncogene2021
34234148Automated and rapid detection of cancer in suspicious axillary lymph nodes in patients with breast cancer.NPJ Breast Cancer2021
33952317Methylated markers accurately distinguish primary central nervous system lymphomas (PCNSL) from other CNS tumors.Clin Epigenetics2021
34001907Running the full human developmental clock in interspecies chimeras using alternative human stem cells with expanded embryonic potential.NPJ Regen Med2021
34165589Retrospective analysis of cancer-specific gene expression panel for thyroid fine needle aspiration specimens.J Cancer Res Clin Oncol2021
34112666Analysis of multispectral imaging with the AstroPath platform informs efficacy of PD-1 blockade.Science2021
31531802High mobility group A1 (HMGA1) protein and gene expression correlate with ER-negativity and poor outcomes in breast cancer.Breast Cancer Res Treat2020
32025567DNA methylation markers predict recurrence-free interval in triple-negative breast cancer.NPJ Breast Cancer2020
32992569Integrated Multiparametric Radiomics and Informatics System for Characterizing Breast Tumor Characteristics with the OncotypeDX Gene Assay.Cancers (Basel)2020
32349388Integrative Transcriptome Analyses of the Human Fallopian Tube: Fimbria and Ampulla-Site of Origin of Serous Carcinoma of the Ovary.Cancers (Basel)2020
30789293Measuring DNA Copy Number Variation Using High-Density Methylation Microarrays.J Comput Biol2019
31300453DNA Methylation Markers for Breast Cancer Detection in the Developing World.Clin Cancer Res2019
31611308Functional Loss of <i>ATRX</i> and <i>TERC</i> Activates Alternative Lengthening of Telomeres (ALT) in LAPC4 Prostate Cancer Cells.Mol Cancer Res2019
31373686Genome-wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types.Int J Cancer2019
31343420Clinicopathologic and Molecular Features of Paired Cases of Metachronous Ovarian Serous Borderline Tumor and Subsequent Serous Carcinoma.Am J Surg Pathol2019
30841906Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.J Immunother Cancer2019
30744692Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.J Immunother Cancer2019
30863929DNA methylation genome-wide analysis in remnant and primary gastric cancers.Gastric Cancer2019
29600241A Standardized Needs Assessment Tool to Inform the Curriculum Development Process for Pediatric Resuscitation Simulation-Based Education in Resource-Limited Settings.Front Pediatr2018
30225619Young age at diagnosis is associated with worse prognosis in the Luminal A breast cancer subtype: a retrospective institutional cohort study.Breast Cancer Res Treat2018
29895573The Mutation-Associated Neoantigen Functional Expansion of Specific T Cells (MANAFEST) Assay: A Sensitive Platform for Monitoring Antitumor Immunity.Cancer Immunol Res2018
30108103Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor Lesions.Clin Cancer Res2018
30486871Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer.Breast Cancer Res2018
29383066Do End-of-Rotation and End-of-Shift Assessments Inform Clinical Competency Committees' (CCC) Decisions?West J Emerg Med2018
27870562Monitoring of Serum DNA Methylation as an Early Independent Marker of Response and Survival in Metastatic Breast Cancer: TBCRC 005 Prospective Biomarker Study.J Clin Oncol2017
28388418Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.Cell2017
28193624Transcriptional Mechanisms of Resistance to Anti-PD-1 Therapy.Clin Cancer Res2017
28452345HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche.Nat Commun2017
29042553Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma.Nat Commun2017
28596308Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.Science2017
27979916Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study.Clin Cancer Res2017
27637888Mutant p53 Together with TGFβ Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer.Clin Cancer Res2017
27001612The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.Gynecol Oncol2016
27982207Comparison of 20% sulfur hexafluoride with air for intraocular tamponade in Descemet membrane endothelial keratoplasty (DMEK).Arq Bras Oftalmol2016
27696867Fecal Metabolome in Hmga1 Transgenic Mice with Polyposis: Evidence for Potential Screen for Early Detection of Precursor Lesions in Colorectal Cancer.J Proteome Res2016
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Collaborators

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
Co-authored papers 16
Co-authored papers 15
Bloomberg-Kimmel Immunotherapy Institute, Johns Hopkins University School of Medicine
Co-authored papers 13
Dana Farber Cancer Institute.
Co-authored papers 12
Johns Hopkins University School of Medicine
Co-authored papers 10
Dana-Farber Cancer Institute
Co-authored papers 8
National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health
Co-authored papers 8
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
Co-authored papers 7
Maastricht University Medical Center
Co-authored papers 7
Johns Hopkins University School of Medicine
Co-authored papers 7
Co-authored papers 6
Co-authored papers 6
Cleveland Clinic.
Co-authored papers 6
The University of Texas MD Anderson Cancer Center
Co-authored papers 5
The Johns Hopkins Hospital
Co-authored papers 5
Co-authored papers 4
Center for Research and Analytics, American Society of Clinical Oncology
Co-authored papers 4
Co-authored papers 4
Oregon Health and Science University
Co-authored papers 4
Roswell Park Comprehensive Cancer Center
Co-authored papers 4
Co-authored papers 4
Ghent University
Co-authored papers 4
Institute for Cell Engineering, The Johns Hopkins University School of Medicine
Co-authored papers 4
Vanderbilt University Medical Center
Co-authored papers 3
University of California
Co-authored papers 3
Johns Hopkins School of Medicine
Co-authored papers 3
Co-authored papers 3
Queen's University
Co-authored papers 3
Yale School of Medicine
Co-authored papers 3
Co-authored papers 3