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Author Details

Vadim N Gladyshev
Brigham and Women's Hospital
1994
424
93
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36670049Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1-imidazoline receptor.Aging Cell2023
37561875DNA methylation networks underlying mammalian traits.Science2023
37657418Biomarkers of aging for the identification and evaluation of longevity interventions.Cell2023
37612507Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice.Nature2023
37500973Multi-omic rejuvenation and life span extension on exposure to youthful circulation.Nat Aging2023
37674040Author Correction: Universal DNA methylation age across mammalian tissues.Nat Aging2023
37563227Universal DNA methylation age across mammalian tissues.Nat Aging2023
37425825Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.bioRxiv2023
37121869Mitigating age-related somatic mutation burden.Trends Mol Med2023
37253838Accelerated transcriptional elongation during aging impairs longevity.Cell Res2023
37386259The meaning of adaptation in aging: insights from cellular senescence, epigenetic clocks and stem cell alterations.Nat Aging2023
37437248Chemically induced reprogramming to reverse cellular aging.Aging (Albany NY)2023
37269831Distinct longevity mechanisms across and within species and their association with aging.Cell2023
37427458Large-scale across species transcriptomic analysis identifies genetic selection signatures associated with longevity in mammals.EMBO J2023
36681595Metabolism, homeostasis, and aging.Trends Endocrinol Metab2023
36638792Loss of epigenetic information as a cause of mammalian aging.Cell2023
34486812A chromosome-level genome of Antechinus flavipes provides a reference for an Australian marsupial genus with male death after mating.Mol Ecol Resour2022
35643315Redox regulation by TXNRD3 during epididymal maturation underlies capacitation-associated mitochondrial activity and sperm motility in mice.J Biol Chem2022
35694726Characterization of naked mole-rat hematopoiesis reveals unique stem and progenitor cell patterns and neotenic traits.EMBO J2022
35753352Selenoprotein TXNRD3 supports male fertility via the redox regulation of spermatogenesis.J Biol Chem2022
37118067In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan.Nat Aging2022
36548410Epigenetic clocks, aging, and cancer.Science2022
36202216SEPHS1: Its evolution, function and roles in development and diseases.Arch Biochem Biophys2022
36008942Selenocysteine Machinery Primarily Supports TXNRD1 and GPX4 Functions and Together They Are Functionally Linked with SCD and PRDX6.Biomolecules2022
36084791The selenoprotein methionine sulfoxide reductase B1 (MSRB1).Free Radic Biol Med2022
36112674Rapamycin treatment during development extends life span and health span of male mice and <i>Daphnia magna</i>.Sci Adv2022
35039495Epigenetic aging of the demographically non-aging naked mole-rat.Nat Commun2022
34972247Emerging rejuvenation strategies-Reducing the biological age.Aging Cell2022
35140209Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis.Nat Commun2022
32980264The Ground Zero of Organismal Life and Aging.Trends Mol Med2021
35602207Genetic and phenotypic analysis of the causal relationship between aging and COVID-19.Commun Med (Lond)2021
36846190Molecular Damage in Aging.Nat Aging2021
33571808Development of a novel fluorescent biosensor for dynamic monitoring of metabolic methionine redox status in cells and tissues.Biosens Bioelectron2021
33765281Assessing Ribosome Distribution Along Transcripts with Polarity Scores and Regression Slope Estimates.Methods Mol Biol2021
33765276Measuring Organ-Specific Translation Elongation Rate in Mice.Methods Mol Biol2021
33608273Naked mole rat TRF1 safeguards glycolytic capacity and telomere replication under low oxygen.Sci Adv2021
33657387James R. Mitchell (1971-2020).Cell Metab2021
35008430Historical Roles of Selenium and Selenoproteins in Health and Development: The Good, the Bad and the Ugly.Int J Mol Sci2021
34411000COVID-19 mortality rate in children is U-shaped.Aging (Albany NY)2021
34733838Lifespan Extension in Long-Lived Vertebrates Rooted in Ecological Adaptation.Front Cell Dev Biol2021
34705500Maintenance of genome sequence integrity in long- and short-lived rodent species.Sci Adv2021
34758328Genomic expansion of Aldh1a1 protects beavers against high metabolic aldehydes from lipid oxidation.Cell Rep2021
34638991Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity.Int J Mol Sci2021
34606617A standard knockout procedure alters expression of adjacent loci at the translational level.Nucleic Acids Res2021
34751131Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast.Elife2021
34543232Applying deductive reasoning and the principles of particle physics to aging research.Aging (Albany NY)2021
34596321Ectopic cervical thymi and no thymic involution until midlife in naked mole rats.Aging Cell2021
34769078Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in <i>Sephs1<sup>-/-</sup></i> Mice.Int J Mol Sci2021
34769022Pathogenic Variants in Selenoproteins and Selenocysteine Biosynthesis Machinery.Int J Mol Sci2021
34247236A Chromosome-Level Genome of the Agile Gracile Mouse Opossum (Gracilinanus agilis).Genome Biol Evol2021
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Collaborators

University of Rochester
Co-authored papers 29
Co-authored papers 24
Barcelona Institute of Science and Technology
Co-authored papers 13
Harvard Medical School
Co-authored papers 12
Co-authored papers 11
Broad Institute of MIT and Harvard
Co-authored papers 7
David Geffen School of Medicine, University of California los angeles
Co-authored papers 7
University of Michigan School of Medicine ann arbor
Co-authored papers 6
Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences
Co-authored papers 5
The Chinese University of Hong Kong
Co-authored papers 5
National Institute on Aging, National Institutes of Health
Co-authored papers 4
University of Copenhagen, Universitetsparken 15
Co-authored papers 4
Vavilov Institute of General Genetics, Russian Academy of Sciences
Co-authored papers 4
Zhongnan Hospital of Wuhan University
Co-authored papers 4
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 3
National Cancer Institute
Co-authored papers 3
Co-authored papers 3
Inc., Salk Institute for Biological Studies
Co-authored papers 3
Science Applications International Corporation/Frederick
Co-authored papers 3
Co-authored papers 3
Catalan Institution for Research and Advanced Studies
Co-authored papers 3
David Geffen School of Medicine
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Joint Genome Institute
Co-authored papers 2
Co-authored papers 2
US Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory
Co-authored papers 2
Macquarie University
Co-authored papers 2
Co-authored papers 2