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Author Details
Full Name
Vadim N Gladyshev
Affiliation
Brigham and Women's Hospital
ORCID
Career Start Year
1994
Papers
424
H Index
93
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36670049
Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1-imidazoline receptor.
Aging Cell
2023
37561875
DNA methylation networks underlying mammalian traits.
Science
2023
37657418
Biomarkers of aging for the identification and evaluation of longevity interventions.
Cell
2023
37612507
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice.
Nature
2023
37500973
Multi-omic rejuvenation and life span extension on exposure to youthful circulation.
Nat Aging
2023
37674040
Author Correction: Universal DNA methylation age across mammalian tissues.
Nat Aging
2023
37563227
Universal DNA methylation age across mammalian tissues.
Nat Aging
2023
37425825
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.
bioRxiv
2023
37121869
Mitigating age-related somatic mutation burden.
Trends Mol Med
2023
37253838
Accelerated transcriptional elongation during aging impairs longevity.
Cell Res
2023
37386259
The meaning of adaptation in aging: insights from cellular senescence, epigenetic clocks and stem cell alterations.
Nat Aging
2023
37437248
Chemically induced reprogramming to reverse cellular aging.
Aging (Albany NY)
2023
37269831
Distinct longevity mechanisms across and within species and their association with aging.
Cell
2023
37427458
Large-scale across species transcriptomic analysis identifies genetic selection signatures associated with longevity in mammals.
EMBO J
2023
36681595
Metabolism, homeostasis, and aging.
Trends Endocrinol Metab
2023
36638792
Loss of epigenetic information as a cause of mammalian aging.
Cell
2023
34486812
A chromosome-level genome of Antechinus flavipes provides a reference for an Australian marsupial genus with male death after mating.
Mol Ecol Resour
2022
35643315
Redox regulation by TXNRD3 during epididymal maturation underlies capacitation-associated mitochondrial activity and sperm motility in mice.
J Biol Chem
2022
35694726
Characterization of naked mole-rat hematopoiesis reveals unique stem and progenitor cell patterns and neotenic traits.
EMBO J
2022
35753352
Selenoprotein TXNRD3 supports male fertility via the redox regulation of spermatogenesis.
J Biol Chem
2022
37118067
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan.
Nat Aging
2022
36548410
Epigenetic clocks, aging, and cancer.
Science
2022
36202216
SEPHS1: Its evolution, function and roles in development and diseases.
Arch Biochem Biophys
2022
36008942
Selenocysteine Machinery Primarily Supports TXNRD1 and GPX4 Functions and Together They Are Functionally Linked with SCD and PRDX6.
Biomolecules
2022
36084791
The selenoprotein methionine sulfoxide reductase B1 (MSRB1).
Free Radic Biol Med
2022
36112674
Rapamycin treatment during development extends life span and health span of male mice and <i>Daphnia magna</i>.
Sci Adv
2022
35039495
Epigenetic aging of the demographically non-aging naked mole-rat.
Nat Commun
2022
34972247
Emerging rejuvenation strategies-Reducing the biological age.
Aging Cell
2022
35140209
Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis.
Nat Commun
2022
32980264
The Ground Zero of Organismal Life and Aging.
Trends Mol Med
2021
35602207
Genetic and phenotypic analysis of the causal relationship between aging and COVID-19.
Commun Med (Lond)
2021
36846190
Molecular Damage in Aging.
Nat Aging
2021
33571808
Development of a novel fluorescent biosensor for dynamic monitoring of metabolic methionine redox status in cells and tissues.
Biosens Bioelectron
2021
33765281
Assessing Ribosome Distribution Along Transcripts with Polarity Scores and Regression Slope Estimates.
Methods Mol Biol
2021
33765276
Measuring Organ-Specific Translation Elongation Rate in Mice.
Methods Mol Biol
2021
33608273
Naked mole rat TRF1 safeguards glycolytic capacity and telomere replication under low oxygen.
Sci Adv
2021
33657387
James R. Mitchell (1971-2020).
Cell Metab
2021
35008430
Historical Roles of Selenium and Selenoproteins in Health and Development: The Good, the Bad and the Ugly.
Int J Mol Sci
2021
34411000
COVID-19 mortality rate in children is U-shaped.
Aging (Albany NY)
2021
34733838
Lifespan Extension in Long-Lived Vertebrates Rooted in Ecological Adaptation.
Front Cell Dev Biol
2021
34705500
Maintenance of genome sequence integrity in long- and short-lived rodent species.
Sci Adv
2021
34758328
Genomic expansion of Aldh1a1 protects beavers against high metabolic aldehydes from lipid oxidation.
Cell Rep
2021
34638991
Selenium and the 15kDa Selenoprotein Impact Colorectal Tumorigenesis by Modulating Intestinal Barrier Integrity.
Int J Mol Sci
2021
34606617
A standard knockout procedure alters expression of adjacent loci at the translational level.
Nucleic Acids Res
2021
34751131
Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast.
Elife
2021
34543232
Applying deductive reasoning and the principles of particle physics to aging research.
Aging (Albany NY)
2021
34596321
Ectopic cervical thymi and no thymic involution until midlife in naked mole rats.
Aging Cell
2021
34769078
Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in <i>Sephs1<sup>-/-</sup></i> Mice.
Int J Mol Sci
2021
34769022
Pathogenic Variants in Selenoproteins and Selenocysteine Biosynthesis Machinery.
Int J Mol Sci
2021
34247236
A Chromosome-Level Genome of the Agile Gracile Mouse Opossum (Gracilinanus agilis).
Genome Biol Evol
2021
1 - 50 of 424
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