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Author Details

Mar??a Molina
UCM & Instituto Ramon y Cajal de Investigaciones Sanitarias (IRYCIS)
1987
92
30
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36797302A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection.Nat Commun2023
37220793Human gasdermin D and MLKL disrupt mitochondria, endocytic traffic and TORC1 signalling in budding yeast.Open Biol2023
37042757The Mitogen-Activated Protein Kinase Slt2 Promotes Asymmetric Cell Cycle Arrest and Reduces TORC1-Sch9 Signaling in Yeast Lacking the Protein Phosphatase Ptc1.Microbiol Spectr2023
36543932Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease.Eur J Hum Genet2023
36806474EvolClustDB: Exploring Eukaryotic Gene Clusters with Evolutionarily Conserved Genomic Neighbourhoods.J Mol Biol2023
36232332Neomycin Interferes with Phosphatidylinositol-4,5-Bisphosphate at the Yeast Plasma Membrane and Activates the Cell Wall Integrity Pathway.Int J Mol Sci2022
35448599Substrates of the MAPK Slt2: Shaping Yeast Cell Integrity.J Fungi (Basel)2022
36555348Manganese Stress Tolerance Depends on Yap1 and Stress-Activated MAP Kinases.Int J Mol Sci2022
34335569Heterologous Expression and Auto-Activation of Human Pro-Inflammatory Caspase-1 in <i>Saccharomyces cerevisiae</i> and Comparison to Caspase-8.Front Immunol2021
33600059A global analysis of the reconstitution of PTEN function by translational readthrough of PTEN pathogenic premature termination codons.Hum Mutat2021
33498635Differential Role of Threonine and Tyrosine Phosphorylation in the Activation and Activity of the Yeast MAPK Slt2.Int J Mol Sci2021
34436186Clotrimazole-Induced Oxidative Stress Triggers Novel Yeast Pkc1-Independent Cell Wall Integrity MAPK Pathway Circuitry.J Fungi (Basel)2021
33993419A walk-through MAPK structure and functionality with the 30-year-old yeast MAPK Slt2.Int Microbiol2021
31218536Modeling human disease in yeast: recreating the PI3K-PTEN-Akt signaling pathway in Saccharomyces cerevisiae.Int Microbiol2020
31834373HaploTypo: a variant-calling pipeline for phased genomes.Bioinformatics2020
32150787Rewiring the yeast cell wall integrity (CWI) pathway through a synthetic positive feedback circuit unveils a novel role for the MAPKKK Ssk2 in CWI pathway activation.FEBS J2020
32298382The TIR-domain containing effectors BtpA and BtpB from Brucella abortus impact NAD metabolism.PLoS Pathog2020
31342212Not just the wall: the other ways to turn the yeast CWI pathway on.Int Microbiol2020
30959830Mitogen-Activated Protein Kinase Phosphatases (MKPs) in Fungal Signaling: Conservation, Function, and Regulation.Int J Mol Sci2019
31779149Expression of Human PTEN-L in a Yeast Heterologous Model Unveils Specific N-Terminal Motifs Controlling PTEN-L Subcellular Localization and Function.Cells2019
29706633A pathogenic role for germline PTEN variants which accumulate into the nucleus.Eur J Hum Genet2018
29982335Educating in antimicrobial resistance awareness: adaptation of the Small World Initiative program to service-learning.FEMS Microbiol Lett2018
30533419A humanized yeast-based toolkit for monitoring phosphatidylinositol 3-kinase activity at both single cell and population levels.Microb Cell2018
29769614Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae.Sci Rep2018
28143957Insights into the pathological mechanisms of p85α mutations using a yeast-based phosphatidylinositol 3-kinase model.Biosci Rep2017
26786099An Analog-sensitive Version of the Protein Kinase Slt2 Allows Identification of Novel Targets of the Yeast Cell Wall Integrity Pathway.J Biol Chem2016
26546002Wide-Ranging Effects of the Yeast Ptc1 Protein Phosphatase Acting Through the MAPK Kinase Mkk1.Genetics2016
26676327The Salmonella effector SteA binds phosphatidylinositol 4-phosphate for subcellular targeting within host cells.Cell Microbiol2016
27216662Laser induced breakdown spectroscopy for the discrimination of Candida strains.Talanta2016
27514817Methods to Study Protein Tyrosine Phosphatases Acting on Yeast MAPKs.Methods Mol Biol2016
26821324Studying Coxiella burnetii Type IV Substrates in the Yeast Saccharomyces cerevisiae: Focus on Subcellular Localization and Protein Aggregation.PLoS One2016
25173100Immunoproteomic profiling of Saccharomyces cerevisiae systemic infection in a murine model.J Proteomics2015
26261079The yeast cell wall integrity pathway signals from recycling endosomes upon elimination of phosphatidylinositol (4,5)-bisphosphate by mammalian phosphatidylinositol 3-kinase.Cell Signal2015
25888283Differential genetic interactions of yeast stress response MAPK pathways.Mol Syst Biol2015
25875300A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity.PLoS One2015
25736922Identification of putative negative regulators of yeast signaling through a screening for protein phosphatases acting on cell wall integrity and mating MAPK pathways.Fungal Genet Biol2015
25448481Yeast-based methods to assess PTEN phosphoinositide phosphatase activity in vivo.Methods2015
24465549A conserved non-canonical docking mechanism regulates the binding of dual specificity phosphatases to cell integrity mitogen-activated protein kinases (MAPKs) in budding and fission yeasts.PLoS One2014
24985344A unified nomenclature and amino acid numbering for human PTEN.Sci Signal2014
24879417Pathogenic potential of Saccharomyces strains isolated from dietary supplements.PLoS One2014
23221999Phosphoproteomic analysis of protein kinase C signaling in Saccharomyces cerevisiae reveals Slt2 mitogen-activated protein kinase (MAPK)-dependent phosphorylation of eisosome core components.Mol Cell Proteomics2013
22706348A yeast-based in vivo bioassay to screen for class I phosphatidylinositol 3-kinase specific inhibitors.J Biomol Screen2012
23015760The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae.Mol Biol Cell2012
21435037Interaction of the Salmonella Typhimurium effector protein SopB with host cell Cdc42 is involved in intracellular replication.Mol Microbiol2011
22006927Distinct docking mechanisms mediate interactions between the Msg5 phosphatase and mating or cell integrity mitogen-activated protein kinases (MAPKs) in Saccharomyces cerevisiae.J Biol Chem2011
21828076A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes.Hum Mol Genet2011
21370058Reverse protein arrays applied to host-pathogen interaction studies.Methods Mol Biol2011
21409566Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms.Mol Genet Genomics2011
20176154Gel and gel-free proteomics to identify Saccharomyces cerevisiae cell surface proteins.J Proteomics2010
20641029Fine regulation of Saccharomyces cerevisiae MAPK pathways by post-translational modifications.Yeast2010
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Collaborators

Humberto Mart??n
Universidad Complutense de Madrid
Co-authored papers 38
Pablo Fernandez-Pi??ar
Co-authored papers 4
Anabel Gil
Co-authored papers 3
Toni Gabald??n
Catalan Institution for Research and Advanced Studies
Co-authored papers 2
Wendell A Lim
University of California san francisco
Co-authored papers 1
Dorothea Fiedler
Leibniz Forschungsinstitut fur Molekulare Pharmakologie (FMP)
Co-authored papers 1
Ping Wei
Fudan University Shanghai Cancer Center
Co-authored papers 1
Marina Marcet-Houben
Institute for Research in Biomedicine (IRB)
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Frank B Furnari
University of California San Diego
Co-authored papers 1
Peter N Devreotes
Co-authored papers 1
Kevan M Shokat
University of California San Francisco
Co-authored papers 1
Nicholas K Tonks
University of Washington
Co-authored papers 1
Asier Erramuzpe
Biocruces Bizkaia Health Research Institute
Co-authored papers 1
Bruce A Vallance
B.C. Children's Hospital
Co-authored papers 1
Suzanne J Baker
Co-authored papers 1
Michael Shales
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
Pedro Beltrao
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Release 1.2