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Author Details

Gabriel Leprivier
Institute of Neuropathology, Heinrich-Heine University Dusseldorf
2006
41
19
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36639156Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.J Immunother Cancer2023
37656187Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma.Acta Neuropathol2023
37976029The long non-coding RNA OTX2-AS1 promotes tumor growth and predicts response to BCL-2 inhibition in medulloblastoma.J Neurooncol2023
36443441Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation.Cell Death Differ2023
35228525Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation.Cell Death Discov2022
35379801EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma.Cell Death Discov2022
35831316The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.Nat Commun2022
34584066The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma.Cell Death Dis2021
32351714How does mTOR sense glucose starvation? AMPK is the usual suspect.Cell Death Discov2020
33371210Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce Resistance against Temozolomide.Cancers (Basel)2020
331774904EBP1/2 are active under standard cell culture conditions to regulate the translation of specific mRNAs.Cell Death Dis2020
31081944The long noncoding RNA TP73-AS1 promotes tumorigenicity of medulloblastoma cells.Int J Cancer2019
31993493RAS-driven oncogenesis is supported by downstream antioxidant programs.Mol Cell Oncol2019
31852884The impact of oncogenic RAS on redox balance and implications for cancer development.Cell Death Dis2019
30867410The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells.Cell Death Dis2019
30704052High-Throughput Screening Identified Compounds Sensitizing Tumor Cells to Glucose Starvation in Culture and VEGF Inhibitors In Vivo.Cancers (Basel)2019
31000598Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.Proc Natl Acad Sci U S A2019
29348556Puromycin labeling does not allow protein synthesis to be measured in energy-starved cells.Cell Death Dis2018
28574509MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation.Cell Death Differ2017
28090356Long noncoding RNA: noncoding and not coded.Cell Death Discov2017
28767324eEF2K protects MYCN-amplified cells from starvation.Cell Cycle2017
28815059Erratum: Long noncoding RNA: noncoding and not coded.Cell Death Discov2017
26829052Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis.Oncogene2016
25464034Stress-mediated translational control in cancer cells.Biochim Biophys Acta2015
25965573Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis.Cancer Cell2015
25800057YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1.J Cell Biol2015
24516159HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.Proc Natl Acad Sci U S A2014
25244326How does oncogene transformation render tumor cells hypersensitive to nutrient deprivation?Bioessays2014
23706743The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation.Cell2013
24342878Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers.Oncotarget2013
24280494[Surviving nutrient deprivation by restraining translation elongation: biological function of the eEF2 kinase].Med Sci (Paris)2013
23798677Mutation of the salt bridge-forming residues in the ETV6-SAM domain interface blocks ETV6-NTRK3-induced cellular transformation.J Biol Chem2013
21941369The AMPK stress response pathway mediates anoikis resistance through inhibition of mTOR and suppression of protein synthesis.Cell Death Differ2012
22967496Identification and quantification of newly synthesized proteins translationally regulated by YB-1 using a novel Click-SILAC approach.J Proteomics2012
221795747th Tuscany Retreat on Cancer Research: genetic profiling, resistance mechanism and novel treatment concepts in cancer.Cell Death Differ2012
21903344A possible role for long non-coding RNA in modulating signaling pathways.Med Hypotheses2011
20001963Caspase cleavage of Ets-1 p51 generates fragments with transcriptional dominant-negative function.Biochem J2010
19022222Ets-1 binds cooperatively to the palindromic Ets-binding sites in the p53 promoter.Biochem Biophys Res Commun2009
19377509Ets-1 p27: a novel Ets-1 isoform with dominant-negative effects on the transcriptional properties and the subcellular localization of Ets-1 p51.Oncogene2009
19465391Ets-1 p51 and p42 isoforms differentially modulate Stromelysin-1 promoter according to induced DNA bend orientation.Nucleic Acids Res2009
16652151Stromelysin-1 expression is activated in vivo by Ets-1 through palindromic head-to-head Ets binding sites present in the promoter.Oncogene2006
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Collaborators

Barak Rotblat
Ben-Gurion University of the Negev
Co-authored papers 20
Poul H Sorensen
British Columbia Cancer Research Centre
Co-authored papers 15
Marc Remke
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 11
Guido Reifenberger
Heinrich Heine University
Co-authored papers 10
Daniel Picard
Groupe Hospitalier Universitaire Pitie-Salpetriere
Co-authored papers 8
Nan Qin
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 6
Thomas G P Gr??newald
German Cancer Research Center
Co-authored papers 6
Anja Stefanski
Universitatsklinikum
Co-authored papers 5
Arndt Borkhardt
Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf
Co-authored papers 5
David Pauck
German Cancer Research Center (DKFZ)
Co-authored papers 4
Jasmin Bartl
German Cancer Research Center (DKFZ)
Co-authored papers 4
Kai St??hler
Universitatsklinikum
Co-authored papers 4
Ute Fischer
Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf
Co-authored papers 4
Frauke-Dorothee Meyer
German Cancer Research Center (DKFZ)
Co-authored papers 4
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 4
Cristina E Tognon
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Viktoria Marquardt
German Cancer Research Center (DKFZ)
Co-authored papers 3
Alberto Delaidelli
Co-authored papers 3
Gian Luca Negri
British Columbia Cancer Research Institute
Co-authored papers 3
Martin E Gleave
University of British Columbia
Co-authored papers 3
Lena Bl??mel
German Cancer Research Center (DKFZ)
Co-authored papers 3
Yuzhuo Wang
University of British Columbia
Co-authored papers 2
Marietta Wolter
Institute of Neuropathology, Heinrich Heine University
Co-authored papers 2
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 2
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 2
Thomas Beez
Heinrich-Heine University Dusseldorf
Co-authored papers 2
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 2
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 2
Till Milde
Hopp Children's Cancer Center Heidelberg (KiTZ)
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Michael Weller
University Hospital and University of Zurich
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Release 1.2