Author details

Full Name

Roman L Bogorad

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37253089	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	Sci Signal	2023
33589614	Identification of a long non-coding RNA regulator of liver carcinoma cell survival.	Cell Death Dis	2021
32577433	Liver-Specific siRNA-Mediated Stat3 or C3 Knockdown Improves the Outcome of Experimental Autoimmune Myocarditis.	Molecular Therapy - Methods and Clinical Development	2020
31855834	InÂ Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation.	Mol Ther Nucleic Acids	2020
32968084	Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes.	Sci Rep	2020
31204997	Liquid-crystal organization of liver tissue.	eLife	2019
29542689	Corrigendum: Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.	Nature	2018
29377001	Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.	Nature Chemical Biology	2018
29131148	Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.	Nature Biotechnology	2017
28890072	Large-Scale Quantitative Proteomics Identifies the Ubiquitin Ligase Nedd4-1 as an Essential Regulator of Liver Regeneration.	Dev Cell	2017
28399412	Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers.	Cancer Cell	2017
28700576	Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.	Nature	2017
29099267	Identification of cell cycle-targeting microRNAs through genome-wide screens.	Cell Cycle	2017
26658687	RNAi-nanoparticulate manipulation of gene expression as a new functional genomics tool in the liver.	Journal of Hepatology	2016
26829318	Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo.	Nat Biotechnol	2016
25937276	Regulation of liver metabolism by the endosomal GTPase Rab5.	Cell Rep	2015
25416068	Control of hepatocyte proliferation and survival by Fgf receptors is essential for liver regeneration in mice.	Gut	2015
25524456	Residue 146 regulates prolactin receptor folding, basal activity and ligand-responsiveness: potential implications in breast tumorigenesis.	Molecular and Cellular Endocrinology	2015
24516150	Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.	Proceedings of the National Academy of Sciences of the United States of America	2014
25355493	Loss of Î±-catenin elicits a cholestatic response and impairs liver regeneration.	Sci Rep	2014
25354018	Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo.	Angew Chem Int Ed Engl	2014
24681508	Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.	Nature Biotechnology	2014
24992693	The roles of individual mammalian argonautes in RNA interference in vivo.	PLoS One	2014
24813696	In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight.	Nat Nanotechnol	2014
24844798	Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice.	Nature Communications	2014
24844558	Knockdown and knockout of Î²1-integrin in hepatocytes impairs liver regeneration through inhibition of growth factor signalling.	Nature Communications	2014
23409044	MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling.	PLoS One	2013
23747253	MICU1 controls both the threshold and cooperative activation of the mitochondrial CaÂ²âº uniporter.	Cell Metab	2013
23344621	Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.	Molecular Therapy - Nucleic Acids	2012
22622570	Rab5 is necessary for the biogenesis of the endolysosomal system in vivo.	Nature	2012
22611156	Treatment of erythropoietin deficiency in mice with systemically administered siRNA.	Blood	2012
21685886	Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.	Nature	2011
21971318	Prolactin regulation of the prostate gland: a female player in a male game.	Nature Reviews Urology	2011
19897676	Characterization of two constitutively active prolactin receptor variants in a cohort of 95 women with multiple breast fibroadenomas.	Journal of Clinical Endocrinology and Metabolism	2010
20699217	Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors.	Proceedings of the National Academy of Sciences of the United States of America	2010
21036240	Identification of gain-of-function variants of the human prolactin receptor.	Methods in Enzymology	2010
20031611	Prolactin levels and the risk of future coronary artery disease in apparently healthy men and women.	Circulation: Cardiovascular Genetics	2009
18779591	Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors.	Proceedings of the National Academy of Sciences of the United States of America	2008
18161917	JAK-STAT pathway in carcinogenesis: is it relevant to cholangiocarcinoma progression?	World Journal of Gastroenterology	2007
16489923	Prolactin receptors in rat cholangiocytes: regulation of level and isoform ratio is sex independent.	Biochemistry (Moscow)	2006
16461560	Long isoform of prolactin receptor predominates in rat intrahepatic bile ducts and further increases under obstructive cholestasis.	Journal of Endocrinology	2006
15835542	[Mechanisms of discrimation of the prolatin physiologic action on the liver at the receptor level of hepatocytes and cholangiocytes].	Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk	2005
15170369	Short forms of membrane receptors: generation and role in hormonal signal transduction.	Biochemistry (Moscow)	2004
15527411	Influence of obstructive cholestasis and sex hormones on the ratio of mRNA of two alternative prolactin receptor isoforms in rat hepatocytes.	Biochemistry (Moscow)	2004
12937675	Expression of prolactin receptors in human liver during cholestasis of different etiology and secondary liver cancer.	Bulletin of Experimental Biology and Medicine	2003
11862718	[The ratio of prolactin receptor isoforms in rat hepatocytes: the effect of obstructive cholestasis].	Molekulyarnaya Biologiya	2002
10776642	[The effect of a periovulatory prolactin imbalance on prolactin receptor expression in rat ovary cell].	Ontogenez	2000
11022263	Expression of prolactin receptors in rat reproductive tissues during periovulatory prolactin imbalance.	Bulletin of Experimental Biology and Medicine	2000