Author details

Full Name

Neal Silverman

Affiliation

ORCID

Career Start Year

1992

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36723053	Dextran/eudragit S-100 based redox sensitive nanoparticles for colorectal cancer therapy.		2023
37828863	Synthesis and validation of click-modified NOD1/2 agonists.		2023
37116499	Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity.		2023
36931278	Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD.	Neuron	2023
35977521	The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways.	Cell Reports	2022
35868778	Biodegradable disulfide crosslinked chitosan/stearic acid nanoparticles for dual drug delivery for colorectal cancer.	Carbohydrate Polymers	2022
36060064	<i>Leishmania amazonensis</i> sabotages host cell SUMOylation for intracellular survival.	iScience	2022
36396707	Retrotransposon activation during Drosophila metamorphosis conditions adult antiviral responses.	Nature Genetics	2022
34373639	cGAS-like receptors put a sting into the evolution of immune defence.	Nature	2021
33826881	Constitutive immune activity promotes JNK- and FoxO-dependent remodeling of Drosophila airways.	Cell Reports	2021
34464427	Editorial overview of Pearls Microbiome Series: E pluribus unum.	PLoS Pathog	2021
32983094	NLRP3 Sensing of Diverse Inflammatory Stimuli Requires Distinct Structural Features.	Frontiers in Immunology	2020
31940269	The Kinase IKKÎ² Regulates a STING-and NF-ÎºB-Dependent Antiviral Response Pathway in Drosophila.	Immunity	2020
31052481	IIV-6 Inhibits NF-ÎºB Responses in .	Viruses	2019
30857831	Regulation of the Drosophila Imd pathway by signaling amyloids.	Insect Biochemistry and Molecular Biology	2019
29746571	p38b and JAK-STAT signaling protect against Invertebrate iridescent virus 6 infection in Drosophila.	PLoS Pathogens	2018
30119996	The Kinase IKKÎ² Regulates a STING- and NF-ÎºB-Dependent Antiviral Response Pathway in Drosophila.	Immunity	2018
29855367	Dehydration triggers ecdysone-mediated recognition-protein priming and elevated anti-bacterial immune responses in Drosophila Malpighian tubule renal cells.	BMC Biology	2018
30463009	The NF-ÎºB Factor Relish Regulates Atg1 Expression and Controls Autophagy.	Cell Reports	2018
28262484	The Antiviral RNA Interference Response Provides Resistance to Lethal Arbovirus Infection and Vertical Transmission in Caenorhabditis elegans.	Current Biology	2017
28388404	Drosophilosophical: Re-thinking Adaptive Immunity in the Fly.	Cell	2017
28539433	SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans.	Journal of Immunology	2017
28377500	Innate immune signaling in is regulated by transforming growth factor Î² (TGFÎ²)-activated kinase (Tak1)-triggered ubiquitin editing.	Journal of Biological Chemistry	2017
28618263	Relish the Thought and Channel Your Chloride, for Bacterial Clearance Depends on It.		2017
29045898	Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-ÎºB Signaling.	Immunity	2017
29276726	Model of Infection.	Bio-protocol	2017
27851920	ReaDAPting the Role of PGRP-SD in Bacterial Sensing and Immune Activation.	Immunity	2016
27280707	Leishmania amazonensis Engages CD36 to Drive Parasitophorous Vacuole Maturation.	PLoS Pathogens	2016
27270400	Control of the innate immune response by the mevalonate pathway.	Nat Immunol	2016
26824654	Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila.	Cell	2016
26856261	Genomic insights into the Ixodes scapularis tick vector of Lyme disease.	Nat Commun	2016
25451614	Differential activation of immune factors in neurons and glia contribute to individual differences in resilience/vulnerability to sleep disruption.	Brain, Behavior, and Immunity	2015
25063877	Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1Î² production in response to Î²-glucans and the fungal pathogen, Candida albicans.	J Immunol	2014
25421701	Immunity in Drosophila melanogaster--from microbial recognition to whole-organism physiology.	Nat Rev Immunol	2014
23721820	The Drosophila IMD pathway in the activation of the humoral immune response.	Developmental and Comparative Immunology	2014
24799678	Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.	Proc Natl Acad Sci U S A	2014
24891502	The caspase-8 homolog Dredd cleaves Imd and Relish but is not inhibited by p35.	Journal of Biological Chemistry	2014
25142573	Genetic rescue of functional senescence in synaptic and behavioral plasticity.	Sleep	2014
24966209	A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection.	Elife	2014
24692555	RNA and Î²-hemolysin of group B Streptococcus induce interleukin-1Î² (IL-1Î²) by activating NLRP3 inflammasomes in mouse macrophages.	Journal of Biological Chemistry	2014
23203927	Dermatophagoides pteronyssinus major allergen 1 activates the innate immune response of the fruit fly Drosophila melanogaster.	Journal of Immunology	2013
23761445	The genome of Anopheles darlingi, the main neotropical malaria vector.	Nucleic Acids Res	2013
23652443	Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity.	EMBO Journal	2013
22127883	Bacterial effectors: learning on the fly.	Advances in Experimental Medicine and Biology	2012
22549468	Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling.	EMBO Journal	2012
22802624	Serine/threonine acetylation of TGFÎ²-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling.	Proceedings of the National Academy of Sciences of the United States of America	2012
22688773	Characterization of poxvirus-encoded proteins that regulate innate immune signaling pathways.	Methods in Molecular Biology	2012
22520459	UnZIPping mechanisms of effector-triggered immunity in animals.		2012
23144495	Cutting edge: FAS (CD95) mediates noncanonical IL-1Î² and IL-18 maturation via caspase-8 in an RIP3-independent manner.	J Immunol	2012
22018470	Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway.	Immunity	2011