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Author Details

Sonja A Dames
Technische Universitat Munchen
1992
38
15
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
30867195NMR- and MD simulation-based structural characterization of the membrane-associating FATC domain of ataxia telangiectasia mutated.J Biol Chem2019
29349619<sup>1</sup>H, <sup>15</sup>N, and <sup>13</sup>C chemical shift assignments of the micelle immersed FAT C-terminal (FATC) domains of the human protein kinases ataxia-telangiectasia mutated (ATM) and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) fused to the B1 domain of streptococcal protein G (GB1).Biomol NMR Assign2018
29024217Target of rapamycin FATC domain as a general membrane anchor: The FKBP-12 like domain of FKBP38 as a case study.Protein Sci2018
29194576NMR analysis of the backbone dynamics of the small GTPase Rheb and its interaction with the regulatory protein FKBP38.FEBS Lett2018
27632081Chemical shift assignment of the intrinsically disordered N-terminus and the rubredoxin domain in the folded metal bound and unfolded oxidized state of mycobacterial protein kinase G.Biomol NMR Assign2016
26632648A Rigorous and Efficient Method To Reweight Very Large Conformational Ensembles Using Average Experimental Data and To Determine Their Relative Information Content.J Chem Theory Comput2016
27810897Oxidative Unfolding of the Rubredoxin Domain and the Natively Disordered N-terminal Region Regulate the Catalytic Activity of Mycobacterium tuberculosis Protein Kinase G.J Biol Chem2016
25386784Subtype-specific modulation of estrogen receptor-coactivator interaction by phosphorylation.ACS Chem Biol2015
26426064Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting.Membranes (Basel)2015
25839674Expression and purification of the natively disordered and redox sensitive metal binding regions of Mycobacterium tuberculosis protein kinase G.Protein Expr Purif2015
25781269One short cysteine-rich sequence pattern - two different disulfide-bonded structures - a molecular dynamics simulation study.J Pept Sci2015
24725177Characterization of the immersion properties of the peripheral membrane anchor of the FATC domain of the kinase "target of rapamycin" by NMR, oriented CD spectroscopy, and MD simulations.J Phys Chem B2014
24704685Characterization of residue-dependent differences in the peripheral membrane association of the FATC domain of the kinase 'target of rapamycin' by NMR and CD spectroscopy.FEBS Lett2014
23671275NMR- and circular dichroism-monitored lipid binding studies suggest a general role for the FATC domain as membrane anchor of phosphatidylinositol 3-kinase-related kinases (PIKK).J Biol Chem2013
22183293Positional screening and NMR structure determination of side-chain-to-side-chain cyclized β3-peptides.Org Biomol Chem2012
22955930In support of the BMRB.Nat Struct Mol Biol2012
22825779A fast and simple method for probing the interaction of peptides and proteins with lipids and membrane-mimetics using GB1 fusion proteins and NMR spectroscopy.Protein Sci2012
22620485The FKBP-rapamycin binding domain of human TOR undergoes strong conformational changes in the presence of membrane mimetics with and without the regulator phosphatidic acid.Biochemistry2012
209276141H, 15N, and 13C assignments of the N-terminal activation domain of Dictyostelium discoideum Formin C.Biomol NMR Assign2011
22033481Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1.J Mol Biol2011
21846933Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C.J Biol Chem2011
20042596Structural basis for the association of the redox-sensitive target of rapamycin FATC domain with membrane-mimetic micelles.J Biol Chem2010
20210365A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1.Biochemistry2010
18313330A fast and simple method to prepare the FKBP-rapamycin binding domain of human target of rapamycin for NMR binding assays.Protein Expr Purif2008
18550521Insights into the low adhesive capacity of human T-cadherin from the NMR structure of Its N-terminal extracellular domain.J Biol Chem2008
171805501H, 13C, and 15N chemical shift assignments for the N-terminal extracellular domain of T-cadherin.J Biomol NMR2007
17724342Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.Proc Natl Acad Sci U S A2007
16917728NMR assignment of the Cyclin T-binding domain of human Hexim1.J Biomol NMR2006
17031964Residual dipolar couplings in short peptides reveal systematic conformational preferences of individual amino acids.J Am Chem Soc2006
15772072The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability.J Biol Chem2005
11959977Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response.Proc Natl Acad Sci U S A2002
10100618Contributions of the ionization states of acidic residues to the stability of the coiled coil domain of matrilin-1.FEBS Lett1999
10369781NMR hydrogen exchange of the OB-fold protein LysN as a function of denaturant: the most conserved elements of structure are the most stable to unfolding.J Mol Biol1999
9699631NMR structure of a parallel homotrimeric coiled coil.Nat Struct Biol1998
9260286Heteronuclear NMR assignments and secondary structure of the coiled coil trimerization domain from cartilage matrix protein in oxidized and reduced forms.Protein Sci1997
8880922A fragment of staphylococcal nuclease with an OB-fold structure shows hydrogen-exchange protection factors in the range reported for "molten globules".Protein Sci1996
7588758Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease.Eur J Biochem1995
1516818Characterization of Caenorhabditis elegans lectin-binding mutants.Genetics1992
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Collaborators

University of Basel
Co-authored papers 11
F. Hoffmann-La Roche Ltd.
Co-authored papers 3
University of California San Francisco
Co-authored papers 1
University of Illinois
Co-authored papers 1
and Center for Structural Biology, Vanderbilt University
Co-authored papers 1
Technische Universitat Munchen (TUM)
Co-authored papers 1
University of Bristol
Co-authored papers 1
The University of Manchester
Co-authored papers 1
Rutgers University
Co-authored papers 1
Washington University School of Medicine
Co-authored papers 1
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers 1
Leicester Institute of Structural and Chemical Biology, University of Leicester
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
The University of Sheffield
Co-authored papers 1
Institute of Systems, The University of Liverpool
Co-authored papers 1
University of California at San Francisco
Co-authored papers 1
Institute of Integrative Biology, University of Liverpool
Co-authored papers 1
Columbia University
Co-authored papers 1
National Institutes of Health
Co-authored papers 1
Zernike Institute for Advanced Materials, University of Groningen
Co-authored papers 1
Co-authored papers 1
University of Oxford
Co-authored papers 1
The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Imperial College London
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Institute for Protein Research, Osaka University
Co-authored papers 1
Sichuan University
Co-authored papers 1
Co-authored papers 1